Detailed information NTG0300833

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: CSC59_RS05645
• Genome accession: NZ_CP030326
• Coordinates: 1050821..1051807 (+)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain AR_474
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 1045821..1056807

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CSC59_RS05620 (CSC59_0768)	opp4B	1046035..1046997 (+)	963	WP_000915997.1	oligopeptide ABC transporter permease	-
CSC59_RS05625 (CSC59_0769)	opp4C	1047009..1047890 (+)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
CSC59_RS05630 (CSC59_0770)	trpS	1047932..1048921 (-)	990	WP_000448934.1	tryptophan--tRNA ligase	-
CSC59_RS05635 (CSC59_0771)	spxA	1049215..1049610 (+)	396	WP_000258003.1	transcriptional regulator SpxA	-
CSC59_RS05640 (CSC59_0772)	mecA	1049981..1050700 (+)	720	WP_001217734.1	adaptor protein MecA	-
CSC59_RS05645 (CSC59_0773)	coiA	1050821..1051807 (+)	987	WP_000959282.1	competence protein CoiA family protein	Machinery gene
CSC59_RS05650 (CSC59_0774)	pepF	1051855..1053663 (+)	1809	WP_000082725.1	oligoendopeptidase F	-
CSC59_RS05655 (CSC59_0775)	yjbH	1054123..1054929 (-)	807	WP_000896697.1	protease adaptor protein YjbH	-
CSC59_RS05660 (CSC59_0776)	-	1054952..1055317 (-)	366	WP_000214070.1	truncated hemoglobin YjbI	-
CSC59_RS05665 (CSC59_0777)	-	1055421..1056014 (-)	594	WP_000224619.1	CYTH domain-containing protein	-
CSC59_RS05670 (CSC59_0778)	-	1056200..1056547 (+)	348	WP_001242103.1	hypothetical protein	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=300833 CSC59_RS05645 WP_000959282.1 1050821..1051807(+) (coiA) [Staphylococcus aureus strain AR_474]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=300833 CSC59_RS05645 WP_000959282.1 1050821..1051807(+) (coiA) [Staphylococcus aureus strain AR_474]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976