Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Regulator
Locus tag   SPH_RS10240 Genome accession   NC_010380
Coordinates   1928194..1928814 (-) Length   206 a.a.
NCBI ID   WP_000839909.1    Uniprot ID   A0A098Z2X2
Organism   Streptococcus pneumoniae Hungary19A-6     
Function   fratricide immunity (predicted from homology)   
Competence regulation

Genomic Context

Location: 1923194..1933814
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPH_RS10215 (SPH_2089) recA 1923571..1924737 (-) 1167 WP_001085462.1 recombinase RecA Machinery gene
  SPH_RS10220 (SPH_2090) cinA 1924792..1926048 (-) 1257 WP_000642704.1 competence/damage-inducible protein A Machinery gene
  SPH_RS10225 (SPH_2091) - 1926133..1927149 (-) 1017 WP_000239278.1 LCP family protein -
  SPH_RS10230 (SPH_2092) - 1927157..1927675 (-) 519 WP_000455536.1 GNAT family N-acetyltransferase -
  SPH_RS10235 (SPH_2093) tsaE 1927665..1928108 (-) 444 WP_000288230.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  SPH_RS10240 (SPH_2094) comM 1928194..1928814 (-) 621 WP_000839909.1 hypothetical protein Regulator
  SPH_RS10245 (SPH_2095) - 1929197..1930060 (-) 864 WP_001093627.1 helix-turn-helix transcriptional regulator -
  SPH_RS14260 - 1930248..1930417 (+) 170 Protein_1943 PhrA family quorum-sensing system peptide -
  SPH_RS10255 (SPH_2096) - 1930732..1931028 (+) 297 WP_000911560.1 lactococcin 972 family bacteriocin -
  SPH_RS10260 (SPH_2097) - 1931131..1933146 (+) 2016 WP_000732372.1 DUF1430 domain-containing protein -
  SPH_RS10265 (SPH_2098) - 1933148..1933780 (+) 633 WP_000571422.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 23540.66 Da        Isoelectric Point: 10.1254

>NTDB_id=30035 SPH_RS10240 WP_000839909.1 1928194..1928814(-) (comM) [Streptococcus pneumoniae Hungary19A-6]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYTGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF

Nucleotide


Download         Length: 621 bp        

>NTDB_id=30035 SPH_RS10240 WP_000839909.1 1928194..1928814(-) (comM) [Streptococcus pneumoniae Hungary19A-6]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTAGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATACTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A098Z2X2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Streptococcus pneumoniae D39

99.515

100

0.995
  comM Streptococcus pneumoniae R6

99.515

100

0.995
  comM Streptococcus pneumoniae TIGR4

99.515

100

0.995
  comM Streptococcus mitis NCTC 12261

38.462

94.66

0.364
  comM Streptococcus mitis SK321

38.462

94.66

0.364

Multiple sequence alignment