Detailed information NTG0300113

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: ETK49_RS15440
• Genome accession: NZ_CP035405
• Coordinates: 2936754..2938019 (-)
• Length: 421 a.a.
• NCBI ID: WP_003184083.1
• Uniprot ID: A0A6I7TM22
• Organism: Bacillus licheniformis strain SRCM103608
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2931754..2943019

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETK49_RS15425 (ETK49_15425)	yihA	2931789..2932376 (-)	588	WP_003184076.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
ETK49_RS15430 (ETK49_15430)	lon	2932373..2934697 (-)	2325	WP_016885551.1	endopeptidase La	-
ETK49_RS15435 (ETK49_15435)	lonB	2934916..2936571 (-)	1656	WP_003184080.1	ATP-dependent protease LonB	-
ETK49_RS15440 (ETK49_15440)	clpX	2936754..2938019 (-)	1266	WP_003184083.1	ATP-dependent protease ATP-binding subunit ClpX	Regulator
ETK49_RS15445 (ETK49_15445)	tig	2938288..2939562 (-)	1275	WP_003184085.1	trigger factor	-
ETK49_RS15450 (ETK49_15450)	ddcA	2939789..2940796 (-)	1008	WP_003184086.1	DNA damage checkpoint antagonist DdcA	-
ETK49_RS15455 (ETK49_15455)	leuD	2940926..2941525 (-)	600	WP_009329311.1	3-isopropylmalate dehydratase small subunit	-
ETK49_RS15460 (ETK49_15460)	leuC	2941538..2942956 (-)	1419	WP_009329313.1	3-isopropylmalate dehydratase large subunit	-

Sequence

Protein

• Length: 421 a.a.
• Molecular weight: 46684.76 Da
• Isoelectric Point: 4.7004

>NTDB_id=300113 ETK49_RS15440 WP_003184083.1 2936754..2938019(-) (clpX) [Bacillus licheniformis strain SRCM103608]
MFKFNEEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEIVEEELGSEEEVEFKDVPKPKEIREILDEYVIGQDQ
AKKSLAVAVYNHYKRINSNSKVDDVELSKSNISMIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILL
KLIQAADYDVEKAEKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNI
LFICGGAFDGIEQIIKRRLGQKVIGFGSDNKHEDLEKEALLSKVLPEDLLRFGLIPEFIGRLPIIASLEPLDEKALVEIL
TKPKNALVKQYRKMLELDDVELVFEDEALTEIAKKAIERKTGARGLRSIIEGIMLDVMFDLPSREDIEKCVITGKTVTDG
EPPRLIMKDGTVVNKDKKTSA

Nucleotide

• Length: 1266 bp

>NTDB_id=300113 ETK49_RS15440 WP_003184083.1 2936754..2938019(-) (clpX) [Bacillus licheniformis strain SRCM103608]
ATGTTTAAATTCAACGAGGAAAAAGGACAATTGAAATGCTCGTTTTGCGGTAAAACACAAGATCAGGTACGCAAGCTTGT
CGCCGGACCAGGCGTATATATATGTGACGAGTGCATCGAACTTTGCACTGAAATTGTAGAAGAGGAACTCGGCTCTGAAG
AAGAAGTGGAGTTCAAAGATGTTCCGAAGCCAAAGGAAATCCGCGAGATTCTTGATGAATACGTCATCGGCCAGGACCAG
GCAAAAAAATCCCTTGCCGTGGCCGTCTACAATCATTACAAGCGGATCAATTCGAACAGCAAAGTCGACGACGTCGAGCT
GTCAAAAAGTAACATTTCCATGATCGGACCGACTGGAAGCGGAAAAACGCTTCTTGCTCAAACGCTTGCCCGCATCCTGA
ATGTGCCGTTCGCCATTGCGGATGCCACGTCGCTTACTGAAGCAGGCTATGTCGGTGAAGATGTGGAGAACATTTTGCTT
AAGCTGATCCAGGCAGCTGACTACGATGTTGAAAAAGCGGAAAAAGGCATTATCTACATCGATGAAATCGATAAAGTGGC
CAGAAAGTCCGAGAACCCTTCGATTACACGCGATGTATCAGGCGAAGGCGTTCAGCAGGCATTGCTTAAAATTCTTGAAG
GTACGGTTGCCAGCGTTCCTCCACAAGGCGGAAGAAAGCATCCTCATCAAGAGTTCATCCAAATTGACACAACCAACATC
CTGTTCATTTGCGGCGGAGCTTTTGACGGAATCGAGCAGATCATCAAGCGCCGTCTCGGCCAGAAGGTCATCGGCTTCGG
CTCTGACAACAAGCATGAAGACCTTGAAAAAGAAGCGCTTCTTTCCAAAGTGCTTCCGGAAGACTTGCTTCGCTTCGGGC
TGATCCCTGAATTCATCGGCCGTCTCCCGATCATCGCAAGCCTTGAGCCGCTGGATGAAAAAGCGCTGGTTGAAATTTTA
ACAAAACCGAAAAACGCGCTTGTTAAACAATATAGAAAAATGCTTGAATTGGATGATGTGGAGCTTGTGTTTGAAGACGA
AGCGCTCACAGAAATCGCTAAAAAAGCAATTGAACGTAAAACAGGAGCACGCGGACTTCGTTCCATTATCGAAGGAATCA
TGCTCGACGTGATGTTTGATCTGCCGTCTCGCGAGGATATTGAAAAATGCGTGATCACAGGCAAAACCGTCACTGACGGC
GAACCGCCGCGTCTCATTATGAAAGACGGCACGGTCGTCAATAAAGACAAAAAAACTTCAGCATAA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (109-305)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (311-389)

• ClpX C4-type zinc finger (zf-C4_ClpX) (11-48)

3D structure

• AlphaFold DB: A0A6I7TM22

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	68.766	94.299	0.648
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	59.413	97.15	0.577