Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   ETK49_RS08130 Genome accession   NZ_CP035405
Coordinates   1558668..1560764 (-) Length   698 a.a.
NCBI ID   WP_016885804.1    Uniprot ID   -
Organism   Bacillus licheniformis strain SRCM103608     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 1553668..1565764
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETK49_RS08100 (ETK49_08100) - 1553813..1554142 (-) 330 WP_011197892.1 YkvA family protein -
  ETK49_RS08105 (ETK49_08105) - 1554361..1554603 (+) 243 WP_003181085.1 aspartyl-phosphate phosphatase Spo0E family protein -
  ETK49_RS08110 (ETK49_08110) - 1554665..1556176 (-) 1512 WP_003181087.1 PAS domain-containing sensor histidine kinase -
  ETK49_RS08115 (ETK49_08115) - 1556414..1556869 (+) 456 WP_003181089.1 MarR family transcriptional regulator -
  ETK49_RS08120 (ETK49_08120) motB 1556894..1557673 (-) 780 WP_003181091.1 flagellar motor protein MotB -
  ETK49_RS08125 (ETK49_08125) motA 1557666..1558469 (-) 804 WP_003181093.1 flagellar motor stator protein MotA -
  ETK49_RS08130 (ETK49_08130) clpE 1558668..1560764 (-) 2097 WP_016885804.1 ATP-dependent protease ATP-binding subunit ClpE Regulator
  ETK49_RS08135 (ETK49_08135) - 1560994..1562028 (+) 1035 WP_003181096.1 hypothetical protein -
  ETK49_RS08140 (ETK49_08140) queC 1562293..1562952 (+) 660 WP_003181098.1 7-cyano-7-deazaguanine synthase QueC -
  ETK49_RS08145 (ETK49_08145) queD 1562955..1563395 (+) 441 WP_003181100.1 6-carboxytetrahydropterin synthase QueD -
  ETK49_RS08150 (ETK49_08150) queE 1563388..1564119 (+) 732 WP_095646519.1 7-carboxy-7-deazaguanine synthase QueE -
  ETK49_RS08155 (ETK49_08155) queF 1564141..1564638 (+) 498 WP_009328607.1 preQ(1) synthase -
  ETK49_RS22945 - 1565311..1565436 (-) 126 WP_016885803.1 hypothetical protein -

Sequence

Protein


Download         Length: 698 a.a.        Molecular weight: 78062.17 Da        Isoelectric Point: 5.5477

>NTDB_id=300055 ETK49_RS08130 WP_016885804.1 1558668..1560764(-) (clpE) [Bacillus licheniformis strain SRCM103608]
MRCQHCQKNEATIRLNMQINFTKKQMDLCEDCYKELTQPSMFSGNHFFGGGGSFFSQPSQAQTQTAAKKGLLDELAVNLT
NAAKTGLIDPVIGRDDEVARVIEILNRRNKNNPVLIGEPGVGKTAVAEGLALKIAEGDVPNKLKNKELYLLDVASLVANT
GIRGQFEERMKQLMKELKERKNAILFIDEIHLLVGAGSAEGSMDAGNILKPALARGELQVIGATTLKEYRQIEKDAALER
RFQPIMVHEPTIEQAAAILNGLKEKYEAYHDVTYSDEAIKACVILSSRYIQDRHLPDKAIDLLDEAGSKANLKIDTVSGE
QASQRLQEIEAEKAKALQEENYELAAKLRDEEEALHKKMESHEEEKRATVEAEDIQAIIEQKTGIPVGKLQHDDQKKMKE
LEANLSSRVIGQKEAVKKVAKAVRRSRAGLKSKNRPVGSFLFVGPTGVGKTELSKRLAEELFGTKDAIIRLDMSEYMEKH
AVSKLIGSPPGYVGHEEAGQLTEKVRRNPYSIVLLDEIEKAHPDVQHMFLQIMEDGRLTDSQGRTVSFKDTVIIMTSNAG
VSEKRTTVGFNREEQVMGEQSMIDSLSGYFKPEFLNRFDSIIEFQPLEKEDLVKIAALLLKELEETLKEQNMTLEVSDEA
KEKIAEIGYHPAFGARPLRRTIQTAVEDQMTDLLLEEEHIKGFAVIVENDEIRVKTTR

Nucleotide


Download         Length: 2097 bp        

>NTDB_id=300055 ETK49_RS08130 WP_016885804.1 1558668..1560764(-) (clpE) [Bacillus licheniformis strain SRCM103608]
ATGCGTTGTCAACATTGTCAAAAAAATGAGGCGACGATTCGCCTAAACATGCAAATCAACTTTACAAAAAAACAAATGGA
TTTATGTGAAGACTGCTATAAAGAGCTGACTCAGCCTTCTATGTTTTCAGGAAATCACTTTTTTGGCGGCGGAGGTTCTT
TCTTCAGCCAGCCATCACAAGCGCAGACGCAAACCGCTGCCAAAAAAGGCTTGCTCGATGAACTTGCCGTCAATTTAACA
AATGCAGCAAAGACCGGCTTGATCGATCCGGTGATCGGCCGCGATGATGAAGTAGCCCGTGTGATCGAGATCTTAAACCG
CAGAAATAAAAACAATCCGGTCTTAATCGGTGAACCGGGCGTCGGTAAAACAGCCGTCGCTGAAGGACTTGCTCTCAAAA
TCGCCGAAGGCGATGTTCCAAATAAATTGAAAAACAAAGAGCTCTACCTGCTTGATGTCGCTTCCCTCGTGGCAAACACC
GGCATCAGAGGGCAATTTGAAGAAAGAATGAAACAGCTGATGAAAGAGCTGAAAGAACGCAAAAACGCAATCTTGTTTAT
TGACGAAATTCACCTTCTTGTCGGGGCCGGCTCTGCAGAAGGCTCCATGGATGCGGGCAACATTTTAAAACCTGCACTTG
CCAGAGGCGAGCTGCAAGTTATCGGCGCTACGACGTTGAAGGAATATCGCCAAATTGAAAAAGATGCGGCGTTAGAGCGG
CGCTTCCAGCCGATCATGGTGCACGAACCGACAATTGAGCAGGCCGCAGCGATTTTAAACGGTCTCAAGGAAAAATACGA
AGCATATCACGATGTGACTTACTCGGATGAAGCGATCAAAGCCTGCGTCATTCTGTCAAGCCGCTATATTCAGGACCGCC
ATCTTCCCGATAAGGCGATCGACCTTTTGGATGAAGCCGGTTCAAAAGCGAACTTGAAAATCGACACGGTCAGCGGTGAA
CAAGCTTCCCAACGCCTGCAAGAAATCGAAGCGGAAAAAGCCAAAGCGCTTCAAGAAGAAAACTACGAGCTTGCAGCAAA
ACTCCGCGACGAAGAAGAAGCGCTGCATAAAAAAATGGAAAGCCATGAGGAAGAAAAACGGGCAACAGTTGAAGCGGAAG
ACATTCAAGCGATCATCGAACAAAAAACCGGCATTCCGGTCGGCAAGCTTCAGCACGACGATCAGAAGAAAATGAAAGAG
CTTGAAGCAAACCTTTCAAGCCGCGTGATCGGTCAAAAAGAAGCGGTGAAAAAAGTGGCAAAAGCCGTCAGAAGAAGCCG
CGCCGGCCTGAAATCAAAAAACAGGCCTGTCGGTTCATTCCTGTTCGTCGGCCCGACAGGTGTCGGTAAAACAGAACTTT
CTAAAAGGCTTGCGGAAGAACTGTTCGGCACGAAGGATGCCATCATCCGCCTCGATATGAGCGAATACATGGAAAAACAC
GCCGTATCAAAGCTGATCGGTTCACCTCCTGGATATGTCGGCCACGAAGAAGCCGGACAGCTTACCGAAAAAGTCCGGAG
GAACCCGTACAGCATCGTTTTGCTCGATGAAATCGAAAAAGCCCATCCCGATGTCCAGCACATGTTCCTGCAAATCATGG
AAGACGGACGTCTGACAGACAGCCAAGGGCGGACGGTCAGCTTTAAAGATACCGTCATTATTATGACAAGCAATGCCGGT
GTATCTGAAAAGCGGACAACCGTCGGTTTTAACCGGGAAGAGCAAGTAATGGGCGAACAATCAATGATCGATTCATTAAG
CGGCTACTTTAAGCCGGAATTCCTGAACAGATTTGACAGCATCATCGAATTCCAGCCGCTCGAAAAAGAAGATCTGGTCA
AGATCGCCGCCCTCTTGCTGAAAGAGCTTGAAGAAACGTTAAAAGAGCAAAACATGACGCTCGAAGTTTCAGATGAGGCA
AAAGAAAAAATCGCTGAAATCGGATACCATCCGGCCTTTGGCGCCCGCCCATTAAGAAGAACCATTCAAACAGCGGTCGA
AGATCAAATGACCGATCTGCTGCTTGAAGAAGAACACATCAAAGGTTTTGCGGTTATCGTTGAAAACGATGAAATCCGGG
TGAAAACAACCAGATAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(607-682)

ATPase family associated with various cellular activities (AAA) (AAA)

(114-245)

AAA lid domain (AAA_lid_9)

(252-350)

AAA domain (Cdc48 subfamily) (AAA_2)

(435-601)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

56.15

100

0.602
  clpE Streptococcus pneumoniae TIGR4

55.481

100

0.595
  clpE Streptococcus pneumoniae Rx1

55.481

100

0.595
  clpE Streptococcus pneumoniae D39

55.481

100

0.595
  clpE Streptococcus pneumoniae R6

55.481

100

0.595
  clpC Lactococcus lactis subsp. cremoris KW2

55.45

100

0.583
  clpC Bacillus subtilis subsp. subtilis str. 168

53.765

95.129

0.511
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

47.52

89.542

0.426
  clpC Streptococcus thermophilus LMD-9

46.226

91.117

0.421
  clpC Streptococcus thermophilus LMG 18311

46.215

90.831

0.42
  clpC Streptococcus pneumoniae D39

46.87

89.255

0.418
  clpC Streptococcus pneumoniae TIGR4

46.87

89.255

0.418
  clpC Streptococcus pneumoniae Rx1

46.87

89.255

0.418
  clpC Streptococcus mutans UA159

47.078

88.252

0.415
  clpA Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

42.998

86.963

0.374