Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ETA57_RS18690 Genome accession   NZ_CP035404
Coordinates   3545818..3546453 (-) Length   211 a.a.
NCBI ID   WP_003185124.1    Uniprot ID   Q65F45
Organism   Bacillus licheniformis strain SRCM103583     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3540818..3551453
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETA57_RS18665 (ETA57_18665) - 3541434..3541601 (-) 168 WP_003185114.1 YvzF family protein -
  ETA57_RS18670 (ETA57_18670) - 3541725..3543167 (+) 1443 WP_016886371.1 spore germination protein -
  ETA57_RS18675 (ETA57_18675) - 3543136..3544236 (+) 1101 WP_016885759.1 endospore germination permease -
  ETA57_RS18680 (ETA57_18680) - 3544233..3545354 (+) 1122 WP_016885758.1 Ger(x)C family spore germination protein -
  ETA57_RS18685 (ETA57_18685) - 3545392..3545781 (+) 390 WP_223254851.1 hypothetical protein -
  ETA57_RS18690 (ETA57_18690) vraR 3545818..3546453 (-) 636 WP_003185124.1 response regulator transcription factor Regulator
  ETA57_RS18695 (ETA57_18695) liaS 3546457..3547521 (-) 1065 WP_003185128.1 two-component system sensor histidine kinase LiaS -
  ETA57_RS18700 (ETA57_18700) liaF 3547518..3548249 (-) 732 WP_003185130.1 cell wall-active antibiotics response protein LiaF -
  ETA57_RS18705 (ETA57_18705) - 3548280..3549143 (-) 864 WP_003185131.1 DUF4097 domain-containing protein -
  ETA57_RS18710 (ETA57_18710) - 3549249..3549932 (-) 684 WP_009329563.1 PspA/IM30 family protein -
  ETA57_RS18715 (ETA57_18715) - 3549953..3550339 (-) 387 WP_003185133.1 protein liaI -

Sequence

Protein


Download         Length: 211 a.a.        Molecular weight: 23095.83 Da        Isoelectric Point: 5.1797

>NTDB_id=299983 ETA57_RS18690 WP_003185124.1 3545818..3546453(-) (vraR) [Bacillus licheniformis strain SRCM103583]
MIRVLLIDDHEMVRMGLAAFLESQPDIEVIGEASDGKRGVELALETKPDVILMDLVMEGMDGIEATKQICRQLADPKIIV
LTSFVDDDKVYPVIEAGALSYLLKTSKASEIADAIRAASVGEPKLEAKVAGKVLSKLRHSAGEQPLHQSLTARELEILKL
VAEGKTNKGIAEELYITIKTVKTHVTNILSKLEVDDRTQAAIYAHRNKLVD

Nucleotide


Download         Length: 636 bp        

>NTDB_id=299983 ETA57_RS18690 WP_003185124.1 3545818..3546453(-) (vraR) [Bacillus licheniformis strain SRCM103583]
GTGATTCGAGTATTGTTAATTGATGATCATGAAATGGTGAGAATGGGGCTGGCCGCTTTCCTGGAATCCCAGCCTGATAT
TGAAGTGATTGGGGAGGCATCAGACGGAAAGCGCGGCGTTGAATTGGCGCTTGAAACCAAACCCGACGTGATTTTGATGG
ATCTTGTGATGGAAGGGATGGACGGAATTGAGGCCACGAAACAAATATGCCGGCAGCTTGCCGATCCGAAAATCATCGTT
CTGACGAGCTTCGTTGATGATGACAAGGTCTATCCGGTCATCGAAGCCGGAGCGCTCAGCTATTTGCTGAAAACGTCGAA
AGCGAGTGAAATCGCCGATGCGATCAGGGCTGCGAGCGTCGGAGAACCAAAGCTTGAAGCCAAAGTCGCAGGAAAAGTGT
TGTCCAAGCTGAGACATTCAGCCGGCGAACAGCCCCTTCATCAATCGCTGACGGCAAGAGAATTGGAAATCCTCAAACTT
GTAGCAGAGGGCAAGACAAACAAAGGTATTGCCGAAGAATTATATATCACCATTAAAACAGTTAAAACGCATGTGACGAA
CATCCTTTCCAAGCTTGAAGTCGACGACCGGACACAAGCCGCAATCTACGCCCACCGAAACAAACTTGTCGACTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(148-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q65F45

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

53.11

99.052

0.526
  degU Bacillus subtilis subsp. subtilis str. 168

36.444

100

0.389