Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   SPH_RS02350 Genome accession   NC_010380
Coordinates   438642..439331 (+) Length   229 a.a.
NCBI ID   WP_000518011.1    Uniprot ID   -
Organism   Streptococcus pneumoniae Hungary19A-6     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 433642..444331
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPH_RS02330 (SPH_0479) gpsB 433721..434062 (+) 342 WP_000094897.1 cell division regulator GpsB -
  SPH_RS02335 (SPH_0480) - 434548..435705 (+) 1158 WP_000711368.1 class I SAM-dependent RNA methyltransferase -
  SPH_RS02340 (SPH_0481) mapZ 435718..437130 (+) 1413 WP_000039263.1 mid-cell-anchored protein MapZ -
  SPH_RS02345 (SPH_0482) gndA 437206..438630 (+) 1425 WP_000158800.1 NADP-dependent phosphogluconate dehydrogenase -
  SPH_RS02350 (SPH_0483) covR 438642..439331 (+) 690 WP_000518011.1 response regulator transcription factor Regulator
  SPH_RS02355 (SPH_0484) cbpC 439430..440449 (+) 1020 WP_000771049.1 choline-binding protein CbpC -
  SPH_RS02360 (SPH_0485) - 440567..441799 (-) 1233 WP_000765667.1 MFS transporter -
  SPH_RS13840 (SPH_0486) - 442076..442717 (-) 642 WP_231293594.1 lanthionine synthetase LanC family protein -
  SPH_RS14175 - 443329..443658 (+) 330 WP_000196978.1 transposase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26880.19 Da        Isoelectric Point: 6.9836

>NTDB_id=29996 SPH_RS02350 WP_000518011.1 438642..439331(+) (covR) [Streptococcus pneumoniae Hungary19A-6]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=29996 SPH_RS02350 WP_000518011.1 438642..439331(+) (covR) [Streptococcus pneumoniae Hungary19A-6]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGCCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACTGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467

Multiple sequence alignment