Detailed information NTG0029973

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: SP70585_RS00505
• Genome accession: NC_012468
• Coordinates: 78419..79312 (+)
• Length: 297 a.a.
• NCBI ID: WP_000343888.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae 70585
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 73419..84312

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SP70585_RS00465 (SP70585_0095)	-	73735..74904 (+)	1170	WP_000366342.1	pyridoxal phosphate-dependent aminotransferase	-
SP70585_RS00470 (SP70585_0096)	recO	74901..75671 (+)	771	WP_000616164.1	DNA repair protein RecO	Machinery gene
SP70585_RS00475 (SP70585_0097)	plsX	75668..76660 (+)	993	WP_000717462.1	phosphate acyltransferase PlsX	-
SP70585_RS00480 (SP70585_0098)	-	76666..76899 (+)	234	WP_000136447.1	acyl carrier protein	-
SP70585_RS00485 (SP70585_0099)	-	76936..77235 (+)	300	Protein_90	transposase family protein	-
SP70585_RS00490 (SP70585_0100)	blpU	77438..77668 (+)	231	WP_001093486.1	bacteriocin-like peptide BlpU	-
SP70585_RS14100 (SP70585_0101)	-	77671..77796 (+)	126	WP_000346297.1	PncF family bacteriocin immunity protein	-
SP70585_RS13725	-	78204..78398 (+)	195	WP_000756776.1	hypothetical protein	-
SP70585_RS00505 (SP70585_0103)	comR	78419..79312 (+)	894	WP_000343888.1	XRE family transcriptional regulator	Regulator
SP70585_RS00510 (SP70585_0104)	-	79855..80151 (+)	297	WP_000837726.1	uberolysin/carnocyclin family circular bacteriocin	-
SP70585_RS00515 (SP70585_0105)	-	80158..81294 (+)	1137	WP_000698828.1	hypothetical protein	-
SP70585_RS11915	-	81291..81773 (+)	483	WP_001232094.1	stage II sporulation protein M	-
SP70585_RS00525 (SP70585_0107)	-	81770..82366 (+)	597	WP_000687787.1	ATP-binding cassette domain-containing protein	-
SP70585_RS00530 (SP70585_0108)	-	82347..82838 (+)	492	WP_000671990.1	hypothetical protein	-

Sequence

Protein

• Length: 297 a.a.
• Molecular weight: 34517.01 Da
• Isoelectric Point: 4.6498

>NTDB_id=29973 SP70585_RS00505 WP_000343888.1 78419..79312(+) (comR) [Streptococcus pneumoniae 70585]
MDELKREIGYKIKTIRRSCGKTQIDICGDESELTIRQLARIENGQALATLPKLLLIADKLGVSLQNIVDVKVIEIPKGFL
KLKDELIHSQTYADKGRIERKEAILEEIYENYYENLPEEEQLIVDVTQARFDIYGSSDVTYGLGLVEEYFQQLLKKKYFS
VNDLLIIELYFFCCAMGLEDKEHFEELAQKVLLCSEYEDKASLVQMEKVLLSLFIQIQTEDSLIYIQTFEKIIAKTRHVF
YRPHLFLLKAKYALFVDKNILEAESFYEKAISLAELLDDQVLVQRILAEKQIDFPTT

Nucleotide

• Length: 894 bp

>NTDB_id=29973 SP70585_RS00505 WP_000343888.1 78419..79312(+) (comR) [Streptococcus pneumoniae 70585]
ATGGATGAGTTGAAACGTGAAATTGGTTATAAAATCAAAACTATTAGGCGATCTTGTGGAAAAACTCAGATAGATATTTG
TGGTGATGAATCAGAGTTGACGATTCGTCAGCTAGCACGTATTGAAAATGGGCAAGCTTTAGCAACACTTCCTAAATTAT
TATTGATTGCGGATAAACTTGGAGTATCATTACAGAATATTGTGGATGTTAAGGTTATAGAGATTCCAAAAGGATTCCTA
AAACTCAAAGATGAGCTGATTCATTCTCAAACCTACGCTGATAAGGGAAGAATCGAACGAAAAGAAGCTATACTTGAGGA
AATATATGAAAACTATTATGAGAATTTGCCTGAGGAAGAGCAGTTAATTGTGGATGTGACACAAGCTCGTTTTGATATTT
ATGGTAGTTCAGATGTGACCTACGGTTTAGGGTTAGTGGAAGAATATTTCCAGCAGTTATTAAAAAAGAAATATTTTTCT
GTAAATGATTTGTTGATTATTGAATTGTATTTCTTTTGTTGTGCTATGGGATTAGAAGATAAAGAACATTTTGAGGAGTT
AGCTCAAAAAGTATTGCTATGTTCAGAATATGAAGATAAGGCTAGCCTAGTTCAAATGGAAAAAGTTCTTCTGAGCCTAT
TTATCCAAATTCAGACAGAAGATAGTCTGATATATATTCAAACATTTGAGAAAATTATTGCTAAAACAAGACATGTTTTT
TACCGACCTCATCTATTTTTGCTAAAGGCAAAATATGCTTTATTTGTAGACAAGAATATTTTAGAGGCAGAAAGTTTCTA
TGAAAAGGCGATTTCTCTAGCAGAATTGCTAGACGATCAGGTATTAGTTCAGAGAATTTTAGCAGAAAAACAGATAGATT
TCCCAACAACCTGA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (76-289)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	36.667	100	0.37