Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ES969_RS17200 Genome accession   NZ_CP035402
Coordinates   3174614..3175249 (-) Length   211 a.a.
NCBI ID   WP_014480830.1    Uniprot ID   -
Organism   Bacillus subtilis strain SRCM103576     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3169614..3180249
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ES969_RS17180 (ES969_17180) yvzF 3170676..3170861 (-) 186 WP_041351712.1 YvzF family protein -
  ES969_RS17185 (ES969_17185) gerAA 3170980..3172428 (+) 1449 WP_129134052.1 spore germination receptor protein GerAA -
  ES969_RS17190 (ES969_17190) gerAB 3172397..3173494 (+) 1098 WP_041333097.1 spore germination receptor protein GerAB -
  ES969_RS17195 (ES969_17195) gerAC 3173491..3174606 (+) 1116 WP_088272470.1 spore germination receptor protein GerAC -
  ES969_RS17200 (ES969_17200) vraR 3174614..3175249 (-) 636 WP_014480830.1 two-component system response regulator LiaR Regulator
  ES969_RS17205 (ES969_17205) liaS 3175227..3176309 (-) 1083 WP_014480831.1 two-component system sensor histidine kinase LiaS -
  ES969_RS17210 (ES969_17210) liaF 3176306..3177031 (-) 726 WP_014480832.1 LiaRS two-component regulatory system accessory protein LiaF -
  ES969_RS17215 (ES969_17215) liaG 3177065..3177937 (-) 873 WP_014480833.1 DUF4097 domain-containing protein -
  ES969_RS17220 (ES969_17220) liaH 3178038..3178715 (-) 678 WP_015714684.1 stress responsive protein LiaH -
  ES969_RS17225 (ES969_17225) liaI 3178742..3179122 (-) 381 WP_014480835.1 cell envelope stress-induced membrane anchor protein LiaI -

Sequence

Protein


Download         Length: 211 a.a.        Molecular weight: 23197.79 Da        Isoelectric Point: 4.9049

>NTDB_id=299693 ES969_RS17200 WP_014480830.1 3174614..3175249(-) (vraR) [Bacillus subtilis strain SRCM103576]
MIRVLLIDDHEMVRMGLAAFLEAQPDIEVIGEASDGSEGVRLAAELSPDVILMDLVMEGMDGIQATKQICRELSDPKIIV
LTSFIDDDKVYPVIEAGALSYLLKTSKAAEIADAIRAASKGEPKLESKVAGKVLSRLRHSGENELPHESLTKRELEILFL
IAEGKTNKEIGEELFITIKTVKTHITNILSKLDVSDRTQAAVYAHRNHLVN

Nucleotide


Download         Length: 636 bp        

>NTDB_id=299693 ES969_RS17200 WP_014480830.1 3174614..3175249(-) (vraR) [Bacillus subtilis strain SRCM103576]
GTGATTCGAGTATTATTGATTGATGATCATGAAATGGTCAGAATGGGGCTCGCGGCTTTTTTGGAGGCGCAGCCCGATAT
TGAAGTCATCGGCGAAGCATCGGACGGCAGCGAAGGTGTTCGGCTTGCTGCGGAACTGTCGCCTGATGTCATTTTAATGG
ACCTTGTCATGGAGGGCATGGATGGCATTCAAGCTACAAAGCAAATTTGCCGGGAGCTTTCTGACCCGAAAATTATTGTG
CTCACTAGCTTCATTGATGATGACAAAGTGTACCCGGTTATTGAAGCTGGCGCGCTCAGCTATCTGTTGAAAACCTCAAA
AGCGGCAGAAATCGCCGATGCCATCCGCGCCGCAAGCAAGGGAGAGCCGAAGCTGGAGTCAAAAGTGGCGGGAAAAGTAT
TATCCAGGCTGCGCCACTCAGGTGAAAACGAGCTCCCTCATGAATCGCTTACGAAACGGGAGCTCGAAATACTCTTCCTG
ATCGCAGAAGGAAAGACAAACAAAGAAATAGGCGAGGAACTGTTTATTACGATTAAAACAGTCAAAACACATATTACCAA
TATTTTATCAAAGCTGGATGTCAGTGACCGGACGCAGGCGGCGGTGTACGCACACCGAAATCATCTCGTGAATTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(148-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.381

99.526

0.521
  degU Bacillus subtilis subsp. subtilis str. 168

37.668

100

0.398

Multiple sequence alignment