Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   ES969_RS09275 Genome accession   NZ_CP035402
Coordinates   1762439..1764322 (+) Length   627 a.a.
NCBI ID   WP_041516431.1    Uniprot ID   -
Organism   Bacillus subtilis strain SRCM103576     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1757439..1769322
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ES969_RS09260 (ES969_09260) ymcA 1758476..1758907 (+) 432 WP_003231834.1 regulatory iron-sulfur-containing complex subunit RicA Regulator
  ES969_RS09265 (ES969_09265) cotE 1759169..1759714 (+) 546 WP_003231833.1 outer spore coat protein CotE -
  ES969_RS09270 (ES969_09270) hexA 1759847..1762423 (+) 2577 WP_014479821.1 DNA mismatch repair protein MutS Machinery gene
  ES969_RS09275 (ES969_09275) hexB 1762439..1764322 (+) 1884 WP_041516431.1 DNA mismatch repair endonuclease MutL Machinery gene
  ES969_RS21875 - 1764758..1764841 (+) 84 WP_235091748.1 XtrA/YqaO family protein -
  ES969_RS22170 (ES969_09280) - 1764884..1765105 (+) 222 Protein_1766 VWA domain-containing protein -
  ES969_RS09285 (ES969_09285) - 1765432..1765680 (+) 249 WP_031600520.1 hypothetical protein -
  ES969_RS09290 (ES969_09290) - 1765731..1766093 (-) 363 WP_033881685.1 Ig-like domain-containing protein -
  ES969_RS09295 (ES969_09295) - 1766366..1767115 (+) 750 WP_014479826.1 hypothetical protein -
  ES969_RS09300 (ES969_09300) - 1767352..1767762 (+) 411 Protein_1770 ArpU family phage packaging/lysis transcriptional regulator -
  ES969_RS09305 (ES969_09305) - 1767762..1768291 (+) 530 Protein_1771 tyrosine-type recombinase/integrase -
  ES969_RS21650 - 1768561..1768713 (+) 153 WP_162175547.1 hypothetical protein -
  ES969_RS21655 - 1769041..1769190 (+) 150 WP_031600526.1 hypothetical protein -

Sequence

Protein


Download         Length: 627 a.a.        Molecular weight: 70572.47 Da        Isoelectric Point: 5.6795

>NTDB_id=299643 ES969_RS09275 WP_041516431.1 1762439..1764322(+) (hexB) [Bacillus subtilis strain SRCM103576]
MAKVIQLSDELSNKIAAGEVVERPASVVKELVENAIDADSTVIEIDIEEAGLASIRVLDNGEGMENEDCKRAFRRHATSK
IKDENDLFRVRTLGFRGEALPSIASVSHLEITTSTGEGAGTKLVLQGGNIISESRSSSRKGTEIVVSNLFFNTPARLKYM
KTVHTELGNITDVVNRIALAHPEVSIRLRHHGKNLLQTNGNGDVRHVLAAIYGTAVAKKMLPLHASSLDFEVKGYIALPE
ITRASRNYMSSVVNGRYIKNFPLVKAVHEGYHTLLPIGRHPITFIEITMDPILVDVNVHPSKLEVRLSKETELHDLIRDG
IKDVFKQQQLIPSAQLPKKSAPVIKNEQQFITFDEKPPERKVPEKAHAPSYSPMKLSSVVKEPIDAEEELPPLQFDAPSI
VDQEQTLEVSDVSEELPETFEQECHEEQQQPASERVPIMYPIGQMHGTYILAQNENGLYIIDQHAAQERIKYEYFREKVG
EVEPEVQDMIVPLTFHYSTNEALIIEQHKQELESVGVFLESFGSNSYIVRCHPAWFPKGEEAELIEEIIQQVLDSKNIDI
KKLREEAAIMMSCKGSIKANRHLRNDEIKALLDDLRSTSDPFTCPHGRPIIIHHSTYEMEKMFKRVM

Nucleotide


Download         Length: 1884 bp        

>NTDB_id=299643 ES969_RS09275 WP_041516431.1 1762439..1764322(+) (hexB) [Bacillus subtilis strain SRCM103576]
GTGGCAAAAGTCATCCAGCTGTCAGATGAGCTTTCAAATAAAATAGCGGCGGGCGAGGTTGTGGAACGGCCCGCCTCAGT
CGTCAAAGAATTGGTGGAAAATGCGATCGACGCTGACAGCACAGTCATTGAAATCGATATTGAGGAAGCAGGCCTTGCAT
CCATTCGGGTCTTGGATAACGGCGAAGGAATGGAGAATGAAGATTGCAAGCGAGCTTTCCGCCGCCACGCAACGAGTAAA
ATAAAAGATGAAAATGATTTATTCAGGGTGAGAACGCTCGGTTTCAGGGGAGAAGCCCTGCCGAGTATCGCGTCAGTCTC
TCATCTGGAGATTACAACAAGCACTGGTGAAGGAGCTGGGACGAAGCTCGTCCTCCAAGGAGGAAACATCATTTCCGAAT
CGCGTTCCTCAAGCAGGAAGGGAACTGAAATTGTCGTTTCCAACCTGTTTTTTAACACACCGGCCCGTTTGAAATATATG
AAAACCGTTCATACAGAGCTTGGAAACATTACAGACGTGGTTAACCGTATTGCTCTGGCGCATCCAGAGGTATCGATCCG
CCTGCGACATCATGGGAAAAACCTGCTTCAAACGAACGGAAACGGAGATGTGCGCCATGTACTGGCAGCGATTTACGGCA
CGGCTGTCGCCAAAAAAATGCTTCCGCTGCATGCGAGCTCCTTGGATTTTGAAGTAAAGGGATATATCGCCCTCCCAGAG
ATTACACGGGCGTCGAGAAACTATATGTCGTCTGTGGTCAATGGCCGTTACATTAAAAATTTCCCGCTCGTCAAAGCGGT
TCATGAAGGCTATCATACGCTTCTGCCGATCGGACGCCATCCGATTACTTTTATAGAAATTACGATGGACCCGATTTTAG
TCGATGTCAATGTGCATCCATCGAAGCTTGAGGTCCGGCTCAGCAAGGAAACAGAGCTTCATGACTTAATTCGTGACGGA
ATTAAAGATGTATTTAAACAGCAGCAGCTGATTCCGAGTGCCCAGCTTCCGAAAAAATCGGCACCTGTTATCAAAAATGA
GCAACAGTTCATAACCTTTGATGAAAAGCCTCCGGAAAGAAAAGTACCGGAAAAAGCGCATGCGCCATCTTATTCACCAA
TGAAGCTCAGCTCAGTCGTGAAAGAGCCGATTGATGCGGAGGAAGAATTGCCTCCTCTCCAATTTGATGCTCCATCTATC
GTTGATCAGGAACAAACCCTTGAGGTGTCCGATGTTTCAGAAGAACTGCCTGAAACATTTGAGCAGGAATGCCATGAGGA
ACAGCAGCAGCCAGCGTCTGAGCGGGTTCCGATTATGTACCCGATCGGCCAGATGCACGGGACTTATATATTGGCACAAA
ACGAAAACGGCCTGTATATTATCGACCAGCACGCCGCCCAAGAACGTATTAAATATGAGTACTTTCGTGAAAAGGTGGGG
GAGGTTGAGCCTGAAGTGCAGGATATGATTGTACCGCTGACGTTCCACTACTCCACAAATGAGGCTTTGATTATTGAACA
GCACAAACAAGAGCTCGAAAGCGTCGGTGTCTTTTTAGAGTCATTCGGCTCTAACAGTTACATCGTCCGCTGCCACCCGG
CCTGGTTTCCAAAGGGAGAAGAAGCAGAGCTTATAGAAGAAATCATTCAGCAGGTGCTCGACTCCAAAAATATAGATATT
AAAAAACTCCGCGAGGAAGCGGCGATTATGATGAGCTGCAAAGGCTCCATCAAAGCAAATCGCCACCTCAGAAACGATGA
AATCAAAGCGCTTCTGGACGACCTCCGAAGCACATCAGACCCATTTACATGCCCGCACGGCCGCCCGATCATCATTCACC
ACTCGACATATGAGATGGAAAAGATGTTCAAACGCGTGATGTAG

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(442-583)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-324)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

45.201

100

0.466

Multiple sequence alignment