Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ES969_RS05280 Genome accession   NZ_CP035402
Coordinates   1002722..1003369 (+) Length   215 a.a.
NCBI ID   WP_069837394.1    Uniprot ID   -
Organism   Bacillus subtilis strain SRCM103576     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 997722..1008369
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ES969_RS05265 (ES969_05265) glpD 997893..999560 (+) 1668 WP_021479678.1 glycerol-3-phosphate dehydrogenase -
  ES969_RS05270 (ES969_05270) pgcA 999692..1001437 (+) 1746 WP_069837393.1 phosphoglucomutase -
  ES969_RS05275 (ES969_05275) yhcY 1001586..1002725 (+) 1140 WP_032721229.1 two-component system sensor histidine kinase YhcY -
  ES969_RS05280 (ES969_05280) vraR 1002722..1003369 (+) 648 WP_069837394.1 two-component system response regulator YhcZ Regulator
  ES969_RS05285 (ES969_05285) yhdA 1003366..1003890 (+) 525 WP_038829245.1 FMN-dependent NADPH-azoreductase -
  ES969_RS05290 (ES969_05290) yhdB 1003905..1004147 (-) 243 WP_003233373.1 YhdB family protein -
  ES969_RS05295 (ES969_05295) yhdC 1004348..1004671 (+) 324 WP_014476269.1 YqzG/YhdC family protein -
  ES969_RS05300 (ES969_05300) lytF 1004713..1006173 (-) 1461 WP_014479292.1 peptidoglycan endopeptidase LytF -
  ES969_RS05305 (ES969_05305) nsrR 1006327..1006767 (-) 441 WP_014479293.1 nitric oxide-sensing transcriptional repressor NsrR -

Sequence

Protein


Download         Length: 215 a.a.        Molecular weight: 24148.79 Da        Isoelectric Point: 6.5025

>NTDB_id=299599 ES969_RS05280 WP_069837394.1 1002722..1003369(+) (vraR) [Bacillus subtilis strain SRCM103576]
MKIVIADDHHVVRKGLRFFFATQDDIEVVGEAATGIEALRVIEETKPDLVLMDLSMPEMDGIQAIKKAIQQFPQTNIIVL
TSYSDQEHVIPALQAGAKAYQLKDTEPEELVKTLRQVHGGEYKLSTAIMPHVLTHMKNQHDPEKEKYYQLTRREKDVLTE
IANGKSNKEIAAALFISEKTVKTHVSNLLAKLEVADRTQAALFAVKYNLNGEISK

Nucleotide


Download         Length: 648 bp        

>NTDB_id=299599 ES969_RS05280 WP_069837394.1 1002722..1003369(+) (vraR) [Bacillus subtilis strain SRCM103576]
ATGAAAATTGTCATTGCTGATGATCATCATGTTGTCAGAAAGGGTCTGCGTTTTTTCTTTGCCACCCAGGATGATATTGA
AGTTGTCGGAGAAGCTGCAACGGGAATAGAAGCTCTCCGTGTCATCGAAGAGACAAAGCCGGATCTTGTGCTAATGGATC
TGTCTATGCCCGAGATGGACGGCATTCAAGCCATTAAAAAAGCAATACAGCAATTTCCGCAGACGAATATCATTGTGCTG
ACGAGCTACTCTGATCAGGAGCACGTCATCCCCGCGCTTCAGGCAGGCGCGAAGGCGTATCAATTAAAGGATACGGAGCC
CGAGGAATTGGTGAAAACACTAAGACAAGTGCATGGTGGCGAATACAAGCTTTCTACAGCTATTATGCCCCATGTGCTAA
CACATATGAAAAATCAGCACGACCCGGAAAAAGAAAAATACTATCAATTAACTAGAAGGGAAAAAGACGTTCTGACTGAA
ATAGCGAACGGGAAAAGCAATAAAGAAATCGCAGCAGCCTTGTTTATTTCAGAAAAAACAGTAAAAACCCATGTATCGAA
TCTTTTAGCAAAACTTGAAGTGGCCGATCGCACGCAAGCAGCGCTTTTCGCAGTGAAATATAACCTGAATGGAGAGATCT
CAAAATGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

45.455

97.209

0.442
  degU Bacillus subtilis subsp. subtilis str. 168

38.428

100

0.409

Multiple sequence alignment