Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   C2G35_RS11935 Genome accession   NZ_CP030137
Coordinates   2237387..2237956 (-) Length   189 a.a.
NCBI ID   WP_000872873.1    Uniprot ID   -
Organism   Staphylococcus aureus strain M51     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2232387..2242956
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C2G35_RS11890 (C2G35_11885) - 2232861..2233469 (-) 609 WP_000020304.1 class I SAM-dependent methyltransferase -
  C2G35_RS11895 (C2G35_11890) rplL 2233644..2234012 (-) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  C2G35_RS11900 (C2G35_11895) rplJ 2234055..2234555 (-) 501 WP_001273085.1 50S ribosomal protein L10 -
  C2G35_RS11910 (C2G35_11905) rplA 2234827..2235519 (-) 693 WP_001074619.1 50S ribosomal protein L1 -
  C2G35_RS11915 (C2G35_11910) rplK 2235727..2236149 (-) 423 WP_001085792.1 50S ribosomal protein L11 -
  C2G35_RS11920 (C2G35_11915) nusG 2236330..2236878 (-) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  C2G35_RS11925 (C2G35_11920) secE 2236891..2237073 (-) 183 WP_001074474.1 preprotein translocase subunit SecE -
  C2G35_RS11930 (C2G35_11925) rpmG 2237129..2237272 (-) 144 WP_001788193.1 50S ribosomal protein L33 -
  C2G35_RS11935 (C2G35_11930) sigH 2237387..2237956 (-) 570 WP_000872873.1 RNA polymerase sigma factor Regulator
  C2G35_RS11940 (C2G35_11935) - 2238037..2238561 (-) 525 WP_000664738.1 NYN domain-containing protein -
  C2G35_RS11945 (C2G35_11940) rlmB 2238561..2239307 (-) 747 WP_129364372.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  C2G35_RS11950 (C2G35_11945) - 2239315..2239719 (-) 405 WP_000370182.1 Mini-ribonuclease 3 -
  C2G35_RS11955 (C2G35_11950) cysS 2239712..2241112 (-) 1401 WP_000631963.1 cysteine--tRNA ligase -
  C2G35_RS11960 (C2G35_11955) cysE 2241096..2241743 (-) 648 WP_001805237.1 serine O-acetyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23028.91 Da        Isoelectric Point: 9.4170

>NTDB_id=299596 C2G35_RS11935 WP_000872873.1 2237387..2237956(-) (sigH) [Staphylococcus aureus strain M51]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=299596 C2G35_RS11935 WP_000872873.1 2237387..2237956(-) (sigH) [Staphylococcus aureus strain M51]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

99.471

100

0.995
  sigH Staphylococcus aureus MW2

98.413

100

0.984

Multiple sequence alignment