Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   DP112_RS08375 Genome accession   NZ_CP030125
Coordinates   1676240..1676929 (-) Length   229 a.a.
NCBI ID   WP_012027645.1    Uniprot ID   -
Organism   Streptococcus suis strain HA1003     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1671240..1681929
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DP112_RS08350 (DP112_08350) - 1671710..1672423 (-) 714 WP_044684119.1 NADPH-dependent oxidoreductase -
  DP112_RS08355 (DP112_08355) dnaI 1672420..1673319 (-) 900 WP_024406637.1 primosomal protein DnaI -
  DP112_RS08360 (DP112_08360) - 1673319..1674470 (-) 1152 WP_024406636.1 replication initiation/membrane attachment protein -
  DP112_RS08365 (DP112_08365) nrdR 1674457..1674948 (-) 492 WP_002938341.1 transcriptional regulator NrdR -
  DP112_RS08370 (DP112_08370) - 1675020..1676150 (-) 1131 WP_114866756.1 AI-2E family transporter -
  DP112_RS08375 (DP112_08375) covR 1676240..1676929 (-) 690 WP_012027645.1 winged helix-turn-helix domain-containing protein Regulator
  DP112_RS08380 (DP112_08380) gndA 1677011..1678438 (-) 1428 WP_002942698.1 NADP-dependent phosphogluconate dehydrogenase -
  DP112_RS08385 (DP112_08385) - 1678535..1679074 (-) 540 WP_014736258.1 DUF177 domain-containing protein -
  DP112_RS08390 (DP112_08390) trxB 1679084..1680001 (-) 918 WP_002942687.1 thioredoxin-disulfide reductase -
  DP112_RS08395 (DP112_08395) - 1680015..1680239 (-) 225 WP_002936682.1 DUF4059 family protein -
  DP112_RS08400 (DP112_08400) - 1680257..1681600 (-) 1344 WP_024406634.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26255.14 Da        Isoelectric Point: 5.3968

>NTDB_id=299498 DP112_RS08375 WP_012027645.1 1676240..1676929(-) (covR) [Streptococcus suis strain HA1003]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHETDFDLILMSFQLSDMSSKELATELLAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=299498 DP112_RS08375 WP_012027645.1 1676240..1676929(-) (covR) [Streptococcus suis strain HA1003]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCTATGGAATTGCAGAAAAAAGACTA
TCTTGTTGATTATGCATCGACAGGGAAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGCAAGGAATTGGCTACAGAACTGTTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACAGAAGTTAGTCAATATGGGGAAGAAGTCCTCTCTTATGCTGTTTCCTACGTAGTGAAGCCCTTTGTCAT
CAGTGATTTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGATTTTATTGACAATAACTGTAAGCAGGTTCACATGC
ATGCGGCCTATCGTGATTTGAAGGTTGATTTTCAAAATCGAACAGTGACTCGAGGTGATGAATTGATTAATTTGACCCGT
CGAGAGTATGATCTGTTGGCGACCTTAATGAATAGCCCAGAGCCTGTTAGTCGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATTAAAACGGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432

Multiple sequence alignment