Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   DP112_RS05030 Genome accession   NZ_CP030125
Coordinates   998390..999616 (-) Length   408 a.a.
NCBI ID   WP_002934974.1    Uniprot ID   G7SE29
Organism   Streptococcus suis strain HA1003     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 993390..1004616
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DP112_RS05005 (DP112_05005) - 993569..994876 (-) 1308 WP_114866490.1 excalibur calcium-binding domain-containing protein -
  DP112_RS05010 (DP112_05010) - 995011..995193 (+) 183 WP_029174066.1 4-oxalocrotonate tautomerase -
  DP112_RS05015 (DP112_05015) lepA 995243..997075 (-) 1833 WP_114866491.1 translation elongation factor 4 -
  DP112_RS05020 (DP112_05020) ndk 997313..997726 (-) 414 WP_105134241.1 nucleoside-diphosphate kinase -
  DP112_RS05025 (DP112_05025) yihA 997749..998336 (-) 588 WP_024417937.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  DP112_RS05030 (DP112_05030) clpX 998390..999616 (-) 1227 WP_002934974.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  DP112_RS05040 (DP112_05040) - 999814..1000326 (-) 513 WP_114866492.1 dihydrofolate reductase -
  DP112_RS05045 (DP112_05045) - 1000664..1001503 (-) 840 WP_014637954.1 thymidylate synthase -
  DP112_RS05050 (DP112_05050) - 1001556..1001858 (-) 303 WP_014637955.1 hypothetical protein -
  DP112_RS05055 (DP112_05055) - 1001870..1002148 (-) 279 WP_024416195.1 hypothetical protein -
  DP112_RS05060 (DP112_05060) - 1002270..1003229 (-) 960 WP_114866493.1 ROK family glucokinase -
  DP112_RS05065 (DP112_05065) - 1003326..1003661 (-) 336 WP_024380703.1 hypothetical protein -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45318.84 Da        Isoelectric Point: 4.6382

>NTDB_id=299483 DP112_RS05030 WP_002934974.1 998390..999616(-) (clpX) [Streptococcus suis strain HA1003]
MAVKHTHELIYCSFCGKNQEEVKKIIAGNNVFICNECVELAQEIIREELAEEVLTDLADTPKPQELLNILNNYVIGQDRA
KRALAVAVYNHYKRINFQDSRDENDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENIL
LKLLQAADFNIDRAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIHVDTKN
ILFIVGGAFDGIEEIVKQRLGEKIIGFGHNNRAIDEKESYMQHIIADDIQKFGIIPELIGRLPVFAALDQLTTEDLVRIL
TEPKNALVKQYQTLLSYDDVELDFDEDALLAIAEKAIERKTGARGLRSIIEETMLDVMFEVPGQDNVKRVRVTKAAVDGK
EKPLLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=299483 DP112_RS05030 WP_002934974.1 998390..999616(-) (clpX) [Streptococcus suis strain HA1003]
ATGGCTGTTAAGCATACCCATGAGTTGATTTATTGCTCATTTTGTGGAAAAAATCAAGAAGAAGTTAAAAAAATTATCGC
AGGGAACAATGTCTTCATTTGTAATGAGTGCGTGGAACTAGCACAGGAAATCATTCGTGAGGAACTGGCAGAAGAAGTTT
TGACAGACTTGGCCGATACGCCAAAGCCACAAGAATTACTCAATATCCTGAACAACTACGTCATCGGACAGGATCGTGCA
AAACGTGCTTTAGCAGTAGCCGTTTACAACCACTACAAACGTATCAATTTCCAAGATAGCCGTGATGAGAACGATGTTGA
TTTGCAAAAATCAAATATCCTCATGATTGGCCCGACTGGTTCCGGAAAAACCTTCCTAGCTCAGACCTTGGCTAAAAGTT
TGAATGTCCCGTTTGCTATTGCTGATGCGACCGCTCTTACTGAGGCGGGTTATGTTGGTGAAGACGTAGAAAATATCCTC
CTCAAACTTTTGCAGGCTGCAGACTTTAACATCGACCGTGCAGAAAGAGGAATTATCTATGTGGATGAAATTGATAAAAT
TGCCAAAAAAGGTGAAAATGTGTCCATTACCCGCGATGTATCTGGTGAAGGTGTCCAGCAAGCTCTCCTAAAAATTATCG
AGGGAACTGTGGCCAGCGTACCACCACAAGGCGGACGCAAACATCCAAACCAAGAAATGATTCACGTGGACACCAAAAAT
ATCCTGTTTATCGTTGGCGGTGCATTTGATGGTATCGAAGAAATCGTCAAGCAGCGTCTCGGTGAAAAAATCATCGGTTT
TGGTCATAATAATCGTGCTATTGATGAAAAAGAATCATACATGCAACATATCATTGCAGACGATATTCAAAAATTCGGTA
TCATTCCAGAGTTGATTGGTCGCTTGCCTGTATTCGCAGCTTTGGACCAATTGACAACAGAGGATTTGGTACGCATTTTG
ACGGAACCAAAGAATGCTCTTGTAAAACAATACCAGACACTCTTGTCTTATGATGACGTGGAGCTTGACTTTGATGAGGA
CGCCTTGTTAGCAATTGCAGAAAAAGCAATTGAACGTAAGACTGGCGCTCGTGGACTTCGTTCCATCATTGAAGAAACGA
TGTTGGATGTCATGTTTGAGGTGCCAGGCCAAGATAACGTTAAACGTGTTCGTGTAACAAAAGCAGCAGTAGACGGTAAG
GAAAAGCCTTTACTAGAAACTGCTTAA

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G7SE29

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

83.13

100

0.833
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.209

98.529

0.574

Multiple sequence alignment