Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   DP111_RS00405 Genome accession   NZ_CP030124
Coordinates   69479..70660 (+) Length   393 a.a.
NCBI ID   WP_024394301.1    Uniprot ID   A0A0M9FEC2
Organism   Streptococcus suis strain SH1510     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 64479..75660
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DP111_RS00390 (DP111_00390) mutL 66053..67990 (+) 1938 WP_004194473.1 DNA mismatch repair endonuclease MutL -
  DP111_RS00395 (DP111_00395) ruvA 68029..68619 (+) 591 WP_015646243.1 Holliday junction branch migration protein RuvA -
  DP111_RS00400 (DP111_00400) - 68873..69442 (+) 570 WP_024394300.1 DNA-3-methyladenine glycosylase I -
  DP111_RS00405 (DP111_00405) cinA 69479..70660 (+) 1182 WP_024394301.1 competence/damage-inducible protein A Machinery gene
  DP111_RS00410 (DP111_00410) recA 70712..71863 (+) 1152 WP_024387809.1 recombinase RecA Machinery gene
  DP111_RS00415 (DP111_00415) spx 72099..72497 (+) 399 WP_002939362.1 transcriptional regulator Spx -
  DP111_RS00420 (DP111_00420) - 72597..72863 (+) 267 WP_002939360.1 IreB family regulatory phosphoprotein -
  DP111_RS00425 (DP111_00425) ruvX 72863..73282 (+) 420 WP_032513707.1 Holliday junction resolvase RuvX -
  DP111_RS00430 (DP111_00430) - 73294..73614 (+) 321 WP_002939343.1 DUF1292 domain-containing protein -
  DP111_RS00435 (DP111_00435) rpsJ 74152..74460 (+) 309 WP_014735259.1 30S ribosomal protein S10 -
  DP111_RS00440 (DP111_00440) rplC 74673..75299 (+) 627 WP_011921686.1 50S ribosomal protein L3 -

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 42998.98 Da        Isoelectric Point: 4.4644

>NTDB_id=299406 DP111_RS00405 WP_024394301.1 69479..70660(+) (cinA) [Streptococcus suis strain SH1510]
MKAELIAVGTEILTGQIINTNAQFLSEKCAELGIDVYFHTAVGDNEQRLLSVLEVAGKRSEIVILCGGLGPTEDDLTKQT
LAAFLGRNLVFDELAMAKLDRFFASRPGRVRTPNNERQAQIVEGSQALQNPAGLAVGGMIEQDGVTYIVLPGPPSELKAM
FSESLLPLLSQSQQQLYSRVLRFFGIGESQLVTVLADLIDKQTDPTLAPYAKVGEVTLRLSTKATSQEEANLRLNQLEEK
ILQHDKLREYFYAYGEENSLVQTVAERLVEKNKSIAIVEQGTGGLLQAELSLALADQPYFSGGKVIGQLGTESGRLSEEA
DCIRQELQADLGLAVSVLIKPESTEDNVLAKVYLTLATTSGISQKEIDLGGYSWQYLRQLACLQAWDFVRNTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=299406 DP111_RS00405 WP_024394301.1 69479..70660(+) (cinA) [Streptococcus suis strain SH1510]
ATGAAAGCAGAACTAATCGCTGTGGGTACAGAGATTTTGACAGGACAAATCATTAATACCAATGCTCAGTTCCTTTCGGA
GAAATGTGCAGAGCTGGGAATTGATGTTTACTTCCACACAGCTGTTGGAGATAATGAACAGAGGCTTTTGTCTGTACTGG
AGGTAGCCGGCAAGCGTAGTGAGATAGTTATTCTCTGTGGAGGACTGGGGCCAACAGAAGATGACTTGACTAAGCAGACC
TTGGCAGCCTTCTTAGGTAGAAATCTTGTGTTTGATGAGTTGGCTATGGCAAAATTAGACCGTTTCTTTGCCAGTCGCCC
AGGTCGTGTCCGTACACCAAATAATGAACGTCAGGCACAGATTGTGGAGGGAAGTCAGGCGCTACAGAATCCAGCTGGTT
TAGCTGTTGGTGGTATGATTGAGCAAGATGGTGTAACCTATATTGTTTTGCCTGGCCCACCAAGTGAGCTCAAGGCCATG
TTTTCTGAGAGTCTCTTACCTTTACTGTCCCAATCTCAGCAGCAACTTTATTCGCGTGTCCTACGTTTTTTTGGCATTGG
TGAAAGCCAGTTAGTGACTGTTTTGGCGGACTTGATTGACAAGCAGACAGACCCAACTCTTGCTCCTTATGCAAAAGTTG
GAGAGGTGACTTTACGCTTGTCCACCAAAGCGACCAGCCAAGAAGAGGCAAATCTACGTTTGAATCAGTTGGAAGAAAAA
ATCTTACAACATGATAAACTGAGAGAATATTTCTATGCTTACGGTGAGGAAAATAGTCTGGTACAGACAGTAGCAGAGCG
ATTGGTGGAAAAGAATAAAAGCATAGCCATCGTCGAACAGGGGACAGGTGGTCTCTTGCAAGCTGAATTGAGCCTGGCTT
TGGCTGATCAGCCGTATTTTAGCGGAGGAAAAGTCATCGGTCAGCTAGGGACAGAATCGGGCAGGCTATCAGAGGAAGCT
GACTGCATTCGGCAGGAGCTGCAAGCTGATTTGGGTTTGGCTGTGTCTGTGCTTATCAAACCGGAATCAACAGAGGACAA
CGTACTTGCAAAAGTATATCTCACTTTGGCTACGACCTCGGGTATTTCCCAAAAAGAGATAGATTTAGGTGGTTATTCGT
GGCAATACCTTCGCCAGCTTGCTTGTCTGCAGGCCTGGGATTTTGTACGAAACACTTTGTGA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0M9FEC2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

94.402

100

0.944
  cinA Streptococcus pneumoniae R6

56.01

100

0.593
  cinA Streptococcus mitis SK321

56.01

100

0.593
  cinA Streptococcus pneumoniae TIGR4

56.01

100

0.593
  cinA Streptococcus pneumoniae Rx1

56.01

100

0.593
  cinA Streptococcus mutans UA159

56.691

100

0.593
  cinA Streptococcus mitis NCTC 12261

55.769

100

0.59
  cinA Streptococcus pneumoniae D39

55.769

100

0.59
  cinA Bacillus subtilis subsp. subtilis str. 168

40.409

99.491

0.402

Multiple sequence alignment