Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ETA18_RS17345 Genome accession   NZ_CP035400
Coordinates   3303971..3304606 (-) Length   211 a.a.
NCBI ID   WP_029318425.1    Uniprot ID   -
Organism   Bacillus subtilis strain SRCM103835     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3298971..3309606
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETA18_RS17325 (ETA18_17325) yvzF 3300028..3300213 (-) 186 WP_003244599.1 YvzF family protein -
  ETA18_RS17330 (ETA18_17330) gerAA 3300331..3301779 (+) 1449 WP_128993402.1 spore germination receptor protein GerAA -
  ETA18_RS17335 (ETA18_17335) gerAB 3301748..3302845 (+) 1098 WP_029318427.1 spore germination receptor protein GerAB -
  ETA18_RS17340 (ETA18_17340) gerAC 3302842..3303963 (+) 1122 WP_122894692.1 spore germination receptor protein GerAC -
  ETA18_RS17345 (ETA18_17345) vraR 3303971..3304606 (-) 636 WP_029318425.1 two-component system response regulator LiaR Regulator
  ETA18_RS17350 (ETA18_17350) liaS 3304584..3305666 (-) 1083 WP_041333103.1 two-component system sensor histidine kinase LiaS -
  ETA18_RS17355 (ETA18_17355) liaF 3305663..3306388 (-) 726 WP_003228510.1 LiaRS two-component regulatory system accessory protein LiaF -
  ETA18_RS17360 (ETA18_17360) liaG 3306422..3307294 (-) 873 WP_041850550.1 DUF4097 domain-containing protein -
  ETA18_RS17365 (ETA18_17365) liaH 3307395..3308072 (-) 678 WP_003228506.1 stress responsive protein LiaH -
  ETA18_RS17370 (ETA18_17370) liaI 3308099..3308479 (-) 381 WP_014480835.1 cell envelope stress-induced membrane anchor protein LiaI -

Sequence

Protein


Download         Length: 211 a.a.        Molecular weight: 23123.77 Da        Isoelectric Point: 5.0163

>NTDB_id=299391 ETA18_RS17345 WP_029318425.1 3303971..3304606(-) (vraR) [Bacillus subtilis strain SRCM103835]
MIRVLLIDDHEMVRMGLAAFLEAQPDIEVIGEASDGSEGVRLAVELSPDVILMDLVMEGMDGIQATKQICRELSDPKIIV
LTSFIDDDKVYPVIEAGALSYLLKTSKAAEIADAIRAASKGEPKLESKVAGKVLSRLRHSGENALPHESLTKRELEILCL
IAEGKTNKEIGEELFITIKTVKTHITNILSKLDVSDRTQAAVYAHRNHLVN

Nucleotide


Download         Length: 636 bp        

>NTDB_id=299391 ETA18_RS17345 WP_029318425.1 3303971..3304606(-) (vraR) [Bacillus subtilis strain SRCM103835]
GTGATTCGAGTATTATTGATTGATGATCATGAAATGGTCAGAATGGGGCTCGCGGCTTTTTTGGAGGCGCAGCCCGATAT
TGAAGTCATCGGCGAAGCATCGGACGGCAGCGAAGGTGTTCGGCTAGCTGTGGAACTGTCGCCTGATGTCATTTTAATGG
ACCTTGTCATGGAGGGCATGGATGGCATTCAAGCTACAAAGCAAATTTGCCGGGAGCTTTCTGACCCGAAAATTATTGTG
CTCACAAGCTTCATTGATGATGACAAAGTGTACCCGGTTATTGAAGCTGGCGCGCTCAGCTATCTGTTGAAAACCTCAAA
AGCGGCAGAAATCGCCGATGCCATCCGCGCCGCAAGCAAGGGAGAGCCGAAGCTAGAGTCAAAAGTGGCGGGAAAAGTAT
TATCCAGGCTGCGCCACTCAGGTGAAAACGCGCTCCCGCATGAATCGCTTACGAAACGGGAGCTCGAAATACTCTGCCTG
ATCGCAGAAGGAAAGACAAACAAAGAAATAGGCGAGGAACTGTTTATTACGATTAAAACAGTCAAAACACATATTACCAA
TATTTTATCAAAGCTGGATGTCAGTGACCGGACGCAGGCGGCGGTGTACGCACACAGAAATCATCTCGTGAATTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.381

99.526

0.521
  degU Bacillus subtilis subsp. subtilis str. 168

38.117

100

0.403