Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   SPP_RS08125 Genome accession   NC_012467
Coordinates   1527282..1527959 (-) Length   225 a.a.
NCBI ID   WP_000548991.1    Uniprot ID   A0A501PEF7
Organism   Streptococcus pneumoniae P1031     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1522282..1532959
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPP_RS08100 (SPP_1648) - 1522454..1523083 (-) 630 WP_000762092.1 NAD(P)-dependent oxidoreductase -
  SPP_RS13570 - 1523322..1523685 (+) 364 Protein_1560 hypothetical protein -
  SPP_RS08110 (SPP_1649) - 1523942..1524265 (+) 324 WP_000422779.1 MazG-like protein -
  SPP_RS08115 (SPP_1650) thrS 1524323..1526266 (+) 1944 WP_000608339.1 threonine--tRNA ligase -
  SPP_RS08120 (SPP_1651) - 1526315..1527289 (-) 975 WP_000887955.1 HAMP domain-containing histidine kinase -
  SPP_RS08125 (SPP_1652) braR 1527282..1527959 (-) 678 WP_000548991.1 response regulator transcription factor Regulator
  SPP_RS08130 (SPP_1653) - 1528115..1529188 (+) 1074 WP_001273814.1 DUF2974 domain-containing protein -
  SPP_RS08135 (SPP_1654) - 1529279..1529581 (-) 303 WP_000281608.1 hypothetical protein -
  SPP_RS08140 (SPP_1655) - 1529649..1530086 (-) 438 WP_001166786.1 Rrf2 family transcriptional regulator -
  SPP_RS08145 (SPP_1656) - 1530162..1531004 (-) 843 WP_000160940.1 metallophosphoesterase -
  SPP_RS08150 (SPP_1657) - 1531116..1531766 (+) 651 WP_000188505.1 metal-dependent transcriptional regulator -
  SPP_RS13910 (SPP_1658) - 1531747..1531938 (+) 192 WP_001846744.1 hypothetical protein -
  SPP_RS08160 (SPP_1659) - 1531964..1532611 (+) 648 WP_000260188.1 nicotinamide mononucleotide transporter -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25936.11 Da        Isoelectric Point: 5.1362

>NTDB_id=29916 SPP_RS08125 WP_000548991.1 1527282..1527959(-) (braR) [Streptococcus pneumoniae P1031]
MHKILLVEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=29916 SPP_RS08125 WP_000548991.1 1527282..1527959(-) (braR) [Streptococcus pneumoniae P1031]
ATGCACAAGATTTTATTAGTGGAAGATGATCAGGTCATTCGTCAACAGGTCGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCGGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCTAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAATGAATTCCAGATTTTA
CGCGTGTTATTTGAGCATGCAGGCAACATCGTAGCACGTGACGACCTGATGCGGGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A501PEF7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

49.083

96.889

0.476
  vicR Streptococcus mutans UA159

35.319

100

0.369

Multiple sequence alignment