Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ES968_RS17220 Genome accession   NZ_CP035395
Coordinates   3209817..3210452 (-) Length   211 a.a.
NCBI ID   WP_014480830.1    Uniprot ID   -
Organism   Bacillus subtilis strain SRCM103697     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3204817..3215452
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ES968_RS17200 (ES968_17200) yvzF 3205880..3206065 (-) 186 WP_003221676.1 YvzF family protein -
  ES968_RS17205 (ES968_17205) gerAA 3206183..3207631 (+) 1449 WP_095010577.1 spore germination receptor protein GerAA -
  ES968_RS17210 (ES968_17210) gerAB 3207600..3208697 (+) 1098 WP_014480828.1 spore germination receptor protein GerAB -
  ES968_RS17215 (ES968_17215) gerAC 3208694..3209809 (+) 1116 WP_095010576.1 spore germination receptor protein GerAC -
  ES968_RS17220 (ES968_17220) vraR 3209817..3210452 (-) 636 WP_014480830.1 two-component system response regulator LiaR Regulator
  ES968_RS17225 (ES968_17225) liaS 3210430..3211512 (-) 1083 WP_014480831.1 two-component system sensor histidine kinase LiaS -
  ES968_RS17230 (ES968_17230) liaF 3211509..3212234 (-) 726 WP_069964309.1 LiaRS two-component regulatory system accessory protein LiaF -
  ES968_RS17235 (ES968_17235) liaG 3212268..3213140 (-) 873 WP_129134385.1 DUF4097 domain-containing protein -
  ES968_RS17240 (ES968_17240) liaH 3213241..3213918 (-) 678 WP_129134386.1 stress responsive protein LiaH -
  ES968_RS17245 (ES968_17245) liaI 3213945..3214325 (-) 381 WP_003228504.1 cell envelope stress-induced membrane anchor protein LiaI -

Sequence

Protein


Download         Length: 211 a.a.        Molecular weight: 23197.79 Da        Isoelectric Point: 4.9049

>NTDB_id=299090 ES968_RS17220 WP_014480830.1 3209817..3210452(-) (vraR) [Bacillus subtilis strain SRCM103697]
MIRVLLIDDHEMVRMGLAAFLEAQPDIEVIGEASDGSEGVRLAAELSPDVILMDLVMEGMDGIQATKQICRELSDPKIIV
LTSFIDDDKVYPVIEAGALSYLLKTSKAAEIADAIRAASKGEPKLESKVAGKVLSRLRHSGENELPHESLTKRELEILFL
IAEGKTNKEIGEELFITIKTVKTHITNILSKLDVSDRTQAAVYAHRNHLVN

Nucleotide


Download         Length: 636 bp        

>NTDB_id=299090 ES968_RS17220 WP_014480830.1 3209817..3210452(-) (vraR) [Bacillus subtilis strain SRCM103697]
GTGATTCGAGTATTATTGATTGATGATCATGAAATGGTCAGAATGGGGCTCGCGGCTTTTTTGGAGGCGCAGCCCGATAT
TGAAGTCATCGGCGAAGCATCGGACGGCAGCGAAGGTGTTCGGCTTGCTGCGGAACTGTCGCCTGATGTCATTTTAATGG
ACCTTGTCATGGAGGGCATGGATGGCATTCAAGCTACAAAGCAAATTTGCCGGGAGCTTTCTGACCCGAAAATTATTGTG
CTCACTAGCTTCATTGATGATGACAAAGTGTACCCGGTTATTGAAGCTGGCGCGCTCAGCTATCTGTTGAAAACCTCAAA
AGCGGCAGAAATCGCCGATGCCATCCGCGCCGCAAGCAAGGGAGAGCCGAAGCTGGAGTCAAAAGTGGCGGGAAAAGTAT
TATCCAGGCTGCGCCACTCAGGTGAAAACGAGCTCCCTCATGAATCGCTTACGAAACGGGAGCTCGAAATACTCTTCCTG
ATCGCAGAAGGAAAGACAAACAAAGAAATAGGCGAGGAACTGTTTATTACGATTAAAACAGTCAAAACACATATTACCAA
TATTTTATCAAAGCTGGATGTCAGTGACCGGACGCAGGCGGCGGTGTACGCACACCGAAATCATCTCGTGAATTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(148-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.381

99.526

0.521
  degU Bacillus subtilis subsp. subtilis str. 168

37.668

100

0.398