Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ES967_RS16785 Genome accession   NZ_CP035394
Coordinates   3217804..3218439 (-) Length   211 a.a.
NCBI ID   WP_003243201.1    Uniprot ID   O32197
Organism   Bacillus subtilis strain SRCM103696     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3212804..3223439
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ES967_RS16765 (ES967_16765) yvzF 3213861..3214046 (-) 186 WP_003244599.1 YvzF family protein -
  ES967_RS16770 (ES967_16770) gerAA 3214164..3215612 (+) 1449 WP_003243555.1 spore germination receptor protein GerAA -
  ES967_RS16775 (ES967_16775) gerAB 3215581..3216678 (+) 1098 WP_009968145.1 spore germination receptor protein GerAB -
  ES967_RS16780 (ES967_16780) gerAC 3216675..3217796 (+) 1122 WP_003243203.1 spore germination receptor protein GerAC -
  ES967_RS16785 (ES967_16785) vraR 3217804..3218439 (-) 636 WP_003243201.1 two-component system response regulator LiaR Regulator
  ES967_RS16790 (ES967_16790) liaS 3218417..3219499 (-) 1083 WP_015251253.1 two-component system sensor histidine kinase LiaS -
  ES967_RS16795 (ES967_16795) liaF 3219496..3220221 (-) 726 WP_014480832.1 LiaRS two-component regulatory system accessory protein LiaF -
  ES967_RS16800 (ES967_16800) liaG 3220255..3221127 (-) 873 WP_003244420.1 DUF4097 domain-containing protein -
  ES967_RS16805 (ES967_16805) liaH 3221228..3221905 (-) 678 WP_003243047.1 stress responsive protein LiaH -
  ES967_RS16810 (ES967_16810) liaI 3221932..3222312 (-) 381 WP_003243447.1 cell envelope stress-induced membrane anchor protein LiaI -

Sequence

Protein


Download         Length: 211 a.a.        Molecular weight: 23124.76 Da        Isoelectric Point: 4.9049

>NTDB_id=298940 ES967_RS16785 WP_003243201.1 3217804..3218439(-) (vraR) [Bacillus subtilis strain SRCM103696]
MIRVLLIDDHEMVRMGLAAFLEAQPDIEVIGEASDGSEGVRLAVELSPDVILMDLVMEGMDGIEATKQICRELSDPKIIV
LTSFIDDDKVYPVIEAGALSYLLKTSKAAEIADAIRAASKGEPKLESKVAGKVLSRLRHSGENALPHESLTKRELEILCL
IAEGKTNKEIGEELFITIKTVKTHITNILSKLDVSDRTQAAVYAHRNHLVN

Nucleotide


Download         Length: 636 bp        

>NTDB_id=298940 ES967_RS16785 WP_003243201.1 3217804..3218439(-) (vraR) [Bacillus subtilis strain SRCM103696]
GTGATTCGAGTATTATTGATTGATGATCATGAAATGGTCAGAATGGGGCTCGCGGCTTTTTTGGAGGCGCAGCCCGATAT
TGAAGTCATCGGCGAAGCATCGGACGGCAGCGAAGGTGTTCGGCTTGCTGTGGAACTGTCGCCTGATGTCATTTTAATGG
ACCTTGTCATGGAGGGCATGGATGGCATTGAAGCTACAAAGCAAATTTGCCGGGAGCTTTCCGACCCGAAAATTATTGTG
CTCACTAGCTTCATTGATGATGACAAAGTGTACCCGGTTATTGAAGCTGGCGCGCTCAGCTATCTGTTGAAAACCTCAAA
AGCGGCAGAAATCGCCGATGCCATCCGCGCCGCAAGCAAGGGAGAGCCGAAGCTGGAGTCAAAAGTGGCGGGAAAAGTAT
TATCCAGGCTGCGCCACTCAGGTGAAAACGCGCTCCCGCATGAATCGCTTACAAAACGGGAGCTCGAAATACTCTGCCTG
ATCGCAGAAGGAAAGACAAACAAAGAAATAGGCGAGGAACTGTTTATTACGATTAAAACAGTCAAAACACATATTACGAA
TATTTTATCAAAGCTGGATGTCAGTGACCGGACGCAGGCGGCGGTGTACGCACACCGAAATCATCTCGTGAATTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB O32197

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.857

99.526

0.526
  degU Bacillus subtilis subsp. subtilis str. 168

38.565

100

0.408