Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   ES965_RS09135 Genome accession   NZ_CP035391
Coordinates   1747883..1749766 (+) Length   627 a.a.
NCBI ID   WP_124059865.1    Uniprot ID   -
Organism   Bacillus subtilis strain SRCM103689     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1742883..1754766
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ES965_RS09120 (ES965_09120) ymcA 1743920..1744351 (+) 432 WP_003231834.1 regulatory iron-sulfur-containing complex subunit RicA Regulator
  ES965_RS09125 (ES965_09125) cotE 1744613..1745158 (+) 546 WP_003231833.1 outer spore coat protein CotE -
  ES965_RS09130 (ES965_09130) hexA 1745291..1747867 (+) 2577 WP_124059864.1 DNA mismatch repair protein MutS Machinery gene
  ES965_RS09135 (ES965_09135) hexB 1747883..1749766 (+) 1884 WP_124059865.1 DNA mismatch repair endonuclease MutL Machinery gene
  ES965_RS09140 (ES965_09140) ymzD 1750166..1750621 (-) 456 WP_080481313.1 regulatory YrvL family protein -
  ES965_RS09145 (ES965_09145) - 1750776..1751333 (-) 558 WP_124059866.1 hypothetical protein -
  ES965_RS09150 (ES965_09150) pksA 1751454..1752071 (+) 618 WP_129092434.1 TetR/AcrR family transcriptional regulator -
  ES965_RS09155 (ES965_09155) pksB 1752261..1752938 (+) 678 WP_124059868.1 MBL fold metallo-hydrolase -
  ES965_RS09160 (ES965_09160) - 1753048..1753314 (+) 267 WP_124059869.1 hypothetical protein -
  ES965_RS09165 (ES965_09165) fabD 1753311..1754177 (+) 867 WP_080529333.1 ACP S-malonyltransferase -

Sequence

Protein


Download         Length: 627 a.a.        Molecular weight: 70504.47 Da        Isoelectric Point: 5.7803

>NTDB_id=298735 ES965_RS09135 WP_124059865.1 1747883..1749766(+) (hexB) [Bacillus subtilis strain SRCM103689]
MAKVIQLSDELSNKIAAGEVVERPASVVKELVENAIDADSTVIEIDIEEAGLASIRVLDNGEGMENEDCKRAFRRHATSK
IKDENDLFRVRTLGFRGEALPSIASVSHLEITTSTGEGAGTKLVLQGGNIISESRSSSRKGTEIVVSNLFFNTPARLKYM
KTVHTELGNITDVVNRIALAHPEVSIRLRHHGKNLLQTNGNGDVRHVLAAIYGTAVAKKMLPLHVSSLDFEVKGYIALPE
ITRASRNYMSSVVNGRYIKNFPLVKAVHEGYHTLLPIGRHPITFIEITMDPILVDVNVHPSKLEVRLSKETELHDLIRDG
IKDVFKQEQLIPSAQLPKKSAPVIKNEQQFITFDEKPPEKKVPEKSTAPSYSPMKLSSVVKEPVDAEEKLPPLQFDAPPI
VDQEQTLEVSDVSAEQPETFEQECHEEQPQPASDRVPIMYPIGQMHGTYILAQNENGLYIIDQHAAQERIKYEYFREKVG
EVEPEVQEMIVPLTFHYSTNETLIIEQHKQELESVGVFLESFGSNSYIVRCHPAWFPKGEEAELIEEIIQQVLDSKNIDI
KKLREEAAIMMSCKGSIKANRHLRNDEIKALLDDLRSTSDPFTCPHGRPIIIHHSTYEMEKMFKRVM

Nucleotide


Download         Length: 1884 bp        

>NTDB_id=298735 ES965_RS09135 WP_124059865.1 1747883..1749766(+) (hexB) [Bacillus subtilis strain SRCM103689]
GTGGCAAAAGTCATCCAGCTGTCAGATGAGCTTTCAAATAAAATAGCGGCGGGCGAGGTTGTGGAACGGCCCGCCTCAGT
CGTCAAAGAATTGGTGGAAAATGCGATCGACGCTGACAGCACAGTCATTGAAATCGATATTGAGGAAGCAGGCCTTGCAT
CCATTCGGGTCTTGGATAACGGCGAAGGAATGGAGAATGAAGATTGCAAGCGAGCTTTCCGCCGCCACGCAACGAGTAAA
ATAAAAGATGAAAATGATTTATTCAGGGTGAGAACGCTCGGTTTCAGGGGAGAAGCTCTGCCGAGTATCGCGTCAGTCTC
TCATCTGGAGATTACAACAAGCACTGGTGAAGGAGCTGGGACGAAGCTCGTCCTCCAAGGAGGAAACATCATTTCCGAAT
CGCGTTCCTCAAGCAGGAAGGGAACTGAAATTGTCGTTTCCAACCTGTTTTTTAACACACCGGCCCGTTTGAAATATATG
AAAACCGTTCATACAGAGCTTGGAAACATTACAGATGTGGTTAACCGTATTGCTCTGGCGCATCCAGAGGTATCGATCCG
CCTGCGCCATCATGGGAAAAACCTGCTTCAAACGAACGGAAACGGAGATGTGCGCCATGTACTGGCAGCGATTTACGGCA
CGGCTGTCGCCAAAAAAATGCTTCCGCTGCATGTGAGCTCCTTGGATTTTGAAGTAAAGGGATATATCGCCCTCCCAGAG
ATTACACGGGCGTCGAGAAACTATATGTCGTCTGTGGTCAATGGCCGTTACATTAAAAATTTCCCGCTCGTCAAAGCGGT
TCATGAAGGCTATCATACGCTTCTGCCGATCGGACGCCATCCGATTACTTTTATAGAAATTACGATGGACCCGATTTTAG
TCGATGTCAACGTGCATCCATCGAAGCTTGAGGTCCGGCTCAGCAAGGAAACAGAGCTTCATGACTTAATTCGTGACGGA
ATTAAAGATGTATTTAAACAGGAGCAGCTGATTCCGAGTGCCCAGCTCCCGAAAAAATCGGCACCTGTAATCAAAAATGA
GCAGCAGTTCATAACCTTTGATGAAAAGCCTCCGGAAAAAAAAGTTCCGGAAAAATCGACTGCGCCATCTTATTCACCGA
TGAAGCTCAGCTCAGTCGTAAAAGAGCCGGTTGATGCGGAGGAAAAATTGCCCCCTCTCCAATTTGATGCTCCTCCTATC
GTTGATCAGGAACAAACCCTTGAGGTGTCCGATGTTTCAGCAGAACAGCCTGAAACATTTGAGCAGGAATGCCATGAGGA
ACAGCCGCAGCCAGCGTCTGATCGGGTTCCAATTATGTACCCGATTGGCCAGATGCACGGGACTTATATATTGGCACAAA
ACGAAAACGGCCTATATATTATCGACCAGCACGCCGCCCAAGAACGTATTAAATATGAGTACTTCCGTGAAAAGGTGGGG
GAGGTTGAGCCTGAGGTGCAGGAGATGATTGTACCGCTGACGTTCCACTACTCCACAAATGAGACTTTGATTATTGAACA
GCACAAACAAGAGCTCGAAAGCGTCGGTGTCTTTTTAGAGTCATTCGGCTCTAACAGTTACATCGTCCGCTGCCACCCAG
CCTGGTTTCCAAAGGGAGAAGAAGCAGAGCTTATAGAAGAAATCATTCAGCAGGTGCTCGACTCCAAAAATATAGATATT
AAAAAACTCCGCGAGGAAGCGGCGATTATGATGAGCTGCAAAGGCTCCATCAAAGCAAATCGCCACCTCAGAAACGACGA
AATCAAAGCGCTTCTGGACGACCTCCGAAGCACATCAGACCCATTTACATGCCCGCACGGCCGCCCGATCATCATTCACC
ACTCGACATATGAGATGGAAAAGATGTTCAAACGCGTGATGTAG

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(442-583)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-324)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

45.342

100

0.466