Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ES963_RS17580 Genome accession   NZ_CP035390
Coordinates   3253233..3253868 (-) Length   211 a.a.
NCBI ID   WP_046160834.1    Uniprot ID   -
Organism   Bacillus subtilis strain SRCM103641     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3248233..3258868
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ES963_RS17560 (ES963_17560) yvzF 3249290..3249475 (-) 186 WP_003228521.1 YvzF family protein -
  ES963_RS17565 (ES963_17565) gerAA 3249593..3251041 (+) 1449 WP_087614703.1 spore germination receptor protein GerAA -
  ES963_RS17570 (ES963_17570) gerAB 3251010..3252107 (+) 1098 WP_041333097.1 spore germination receptor protein GerAB -
  ES963_RS17575 (ES963_17575) gerAC 3252104..3253225 (+) 1122 WP_041333099.1 spore germination receptor protein GerAC -
  ES963_RS17580 (ES963_17580) vraR 3253233..3253868 (-) 636 WP_046160834.1 two-component system response regulator LiaR Regulator
  ES963_RS17585 (ES963_17585) liaS 3253846..3254928 (-) 1083 WP_014480831.1 two-component system sensor histidine kinase LiaS -
  ES963_RS17590 (ES963_17590) liaF 3254925..3255650 (-) 726 WP_014480832.1 LiaRS two-component regulatory system accessory protein LiaF -
  ES963_RS17595 (ES963_17595) liaG 3255684..3256553 (-) 870 WP_129093114.1 DUF4097 domain-containing protein -
  ES963_RS17600 (ES963_17600) liaH 3256654..3257331 (-) 678 WP_129093115.1 stress responsive protein LiaH -
  ES963_RS17605 (ES963_17605) liaI 3257358..3257738 (-) 381 WP_014480835.1 cell envelope stress-induced membrane anchor protein LiaI -

Sequence

Protein


Download         Length: 211 a.a.        Molecular weight: 23095.72 Da        Isoelectric Point: 5.0163

>NTDB_id=298633 ES963_RS17580 WP_046160834.1 3253233..3253868(-) (vraR) [Bacillus subtilis strain SRCM103641]
MIRVLLIDDHEMVRMGLAAFLEAQPDIEVIGEASDGSEGVRLAAELSPDVILMDLVMEGMDGIQATKQICRELSDPKIIV
LTSFIDDDKVYPVIEAGALSYLLKTSKAAEIADAIRAASKGEPKLESKVAGKVLSRLRHSGENALPHESLTKRELEILCL
IAEGKTNKEIGEELFITIKTVKTHITNILSKLDVSDRTQAAVYAHRNHLVN

Nucleotide


Download         Length: 636 bp        

>NTDB_id=298633 ES963_RS17580 WP_046160834.1 3253233..3253868(-) (vraR) [Bacillus subtilis strain SRCM103641]
GTGATTCGAGTATTATTGATTGATGATCATGAAATGGTCAGAATGGGGCTCGCGGCTTTTTTGGAGGCGCAGCCCGATAT
TGAAGTCATCGGCGAAGCATCGGACGGCAGCGAAGGTGTTCGGCTTGCTGCGGAACTGTCGCCTGATGTCATTTTAATGG
ACCTTGTCATGGAGGGCATGGATGGCATTCAAGCTACAAAGCAAATTTGCCGGGAGCTTTCTGACCCGAAAATTATTGTG
CTCACTAGCTTCATTGATGATGACAAAGTGTACCCGGTTATTGAAGCTGGCGCGCTCAGCTATCTGTTGAAAACCTCAAA
AGCGGCAGAAATCGCCGATGCCATCCGCGCCGCAAGCAAGGGAGAGCCGAAGCTGGAGTCAAAAGTGGCGGGAAAAGTAT
TATCCAGGTTGCGCCACTCAGGTGAAAACGCGCTCCCGCATGAATCGCTTACGAAACGGGAGCTCGAAATACTCTGCCTG
ATCGCAGAAGGAAAGACAAACAAAGAAATAGGCGAGGAACTGTTTATTACGATTAAAACAGTCAAAACACATATTACGAA
TATTTTATCAAAGCTGGATGTCAGTGACCGGACGCAGGCGGCGGTGTACGCACACCGAAATCATCTCGTGAATTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.381

99.526

0.521
  degU Bacillus subtilis subsp. subtilis str. 168

38.117

100

0.403