Detailed information    

insolico Bioinformatically predicted

Overview

Name   brsR   Type   Regulator
Locus tag   SPP_RS01145 Genome accession   NC_012467
Coordinates   194015..194455 (-) Length   146 a.a.
NCBI ID   WP_000861968.1    Uniprot ID   -
Organism   Streptococcus pneumoniae P1031     
Function   antagonizing the proteolysis of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 189015..199455
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPP_RS01120 (SPP_0225) - 189276..190562 (+) 1287 WP_000278864.1 response regulator transcription factor -
  SPP_RS01125 (SPP_0226) - 190614..191147 (+) 534 WP_000729037.1 hypothetical protein -
  SPP_RS01130 (SPP_0227) nrdI 191225..191695 (+) 471 WP_000849618.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
  SPP_RS01135 (SPP_0228) - 191988..193250 (-) 1263 WP_000075789.1 NRAMP family divalent metal transporter -
  SPP_RS01140 (SPP_0229) - 193560..194018 (-) 459 WP_000745054.1 DUF3021 domain-containing protein -
  SPP_RS01145 (SPP_0230) brsR 194015..194455 (-) 441 WP_000861968.1 LytTR family DNA-binding domain-containing protein Regulator
  SPP_RS01150 (SPP_0231) hexB 194661..196610 (+) 1950 WP_000018164.1 DNA mismatch repair endonuclease MutL Machinery gene
  SPP_RS01155 (SPP_0232) ribE 196935..197402 (-) 468 WP_001099502.1 6,7-dimethyl-8-ribityllumazine synthase -
  SPP_RS01160 (SPP_0233) - 197403..198608 (-) 1206 WP_000456639.1 bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II -
  SPP_RS01165 (SPP_0234) ribE 198628..199263 (-) 636 WP_000493842.1 riboflavin synthase -

Sequence

Protein


Download         Length: 146 a.a.        Molecular weight: 17137.81 Da        Isoelectric Point: 5.9797

>NTDB_id=29857 SPP_RS01145 WP_000861968.1 194015..194455(-) (brsR) [Streptococcus pneumoniae P1031]
MKVELQISETYEEEKLIVQAPQPTDKVQKVIEFAENLDQREKIKGKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSI
DLRLYQVLKLLPTNFIQISQSEIINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL

Nucleotide


Download         Length: 441 bp        

>NTDB_id=29857 SPP_RS01145 WP_000861968.1 194015..194455(-) (brsR) [Streptococcus pneumoniae P1031]
ATGAAAGTAGAACTACAGATTAGTGAGACTTACGAGGAGGAAAAGCTGATTGTCCAAGCACCTCAGCCGACAGATAAAGT
CCAGAAAGTCATCGAGTTCGCAGAAAATCTGGACCAAAGAGAAAAAATCAAAGGGAAAATCGATGATCAGGTCTATCTAG
TTGAGATTGGCAAGATTCAGCGCTTCTATATCGAGAATCGGAAGGTTCTAGCAGAAACCGCGAGTCAGACCTACAGCATT
GATTTGCGACTCTATCAGGTTCTTAAACTCTTGCCAACCAATTTTATCCAAATTTCCCAATCAGAAATCATCAATATCGA
TTCCATCTCTCACCTCAAGCTCACGCCAAACGGTCTGGTAGAAATTTTCTTGAAAAACGAAAGCTTCACCTACTCTTCAC
GCCGTTATCTAAAAACCATCAAGGAGAAATTAGAACTATGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(50-144)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  brsR Streptococcus mutans UA159

36.054

100

0.363