Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   DK877_RS06730 Genome accession   NZ_CP030023
Coordinates   1340205..1341431 (-) Length   408 a.a.
NCBI ID   WP_002934974.1    Uniprot ID   G7SE29
Organism   Streptococcus suis strain ISU2414     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1335205..1346431
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK877_RS06700 - 1335238..1335462 (-) 225 WP_002934981.1 hypothetical protein -
  DK877_RS06705 (DK877_06925) - 1335524..1336831 (-) 1308 WP_002934980.1 excalibur calcium-binding domain-containing protein -
  DK877_RS06710 (DK877_06930) - 1336966..1337148 (+) 183 WP_002934978.1 4-oxalocrotonate tautomerase -
  DK877_RS06715 (DK877_06935) lepA 1337198..1339030 (-) 1833 WP_002934977.1 translation elongation factor 4 -
  DK877_RS06720 (DK877_06940) ndk 1339126..1339539 (-) 414 WP_002934976.1 nucleoside-diphosphate kinase -
  DK877_RS06725 (DK877_06945) yihA 1339562..1340149 (-) 588 WP_002934975.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  DK877_RS06730 (DK877_06950) clpX 1340205..1341431 (-) 1227 WP_002934974.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  DK877_RS06735 (DK877_06960) - 1341629..1342141 (-) 513 WP_002934971.1 dihydrofolate reductase -
  DK877_RS06740 (DK877_06965) - 1342479..1343318 (-) 840 WP_002934970.1 thymidylate synthase -
  DK877_RS06745 (DK877_06970) - 1343371..1343673 (-) 303 WP_002934969.1 hypothetical protein -
  DK877_RS06750 (DK877_06975) - 1343685..1343963 (-) 279 WP_002934968.1 hypothetical protein -
  DK877_RS06755 (DK877_06980) - 1344090..1345049 (-) 960 WP_002934967.1 ROK family glucokinase -
  DK877_RS06760 (DK877_06985) - 1345145..1345480 (-) 336 WP_002934966.1 hypothetical protein -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45318.84 Da        Isoelectric Point: 4.6382

>NTDB_id=298492 DK877_RS06730 WP_002934974.1 1340205..1341431(-) (clpX) [Streptococcus suis strain ISU2414]
MAVKHTHELIYCSFCGKNQEEVKKIIAGNNVFICNECVELAQEIIREELAEEVLTDLADTPKPQELLNILNNYVIGQDRA
KRALAVAVYNHYKRINFQDSRDENDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENIL
LKLLQAADFNIDRAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIHVDTKN
ILFIVGGAFDGIEEIVKQRLGEKIIGFGHNNRAIDEKESYMQHIIADDIQKFGIIPELIGRLPVFAALDQLTTEDLVRIL
TEPKNALVKQYQTLLSYDDVELDFDEDALLAIAEKAIERKTGARGLRSIIEETMLDVMFEVPGQDNVKRVRVTKAAVDGK
EKPLLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=298492 DK877_RS06730 WP_002934974.1 1340205..1341431(-) (clpX) [Streptococcus suis strain ISU2414]
ATGGCTGTTAAGCATACACATGAGCTAATCTATTGCTCATTTTGCGGAAAAAATCAAGAAGAAGTTAAAAAAATTATCGC
AGGAAACAATGTCTTCATTTGTAATGAGTGCGTGGAACTAGCACAGGAAATCATTCGTGAGGAACTGGCAGAAGAAGTTT
TGACAGACTTGGCCGATACGCCAAAGCCACAAGAATTACTCAATATTCTGAACAACTACGTCATCGGACAGGATCGTGCA
AAACGTGCTTTAGCAGTAGCCGTTTACAACCACTACAAACGTATCAATTTCCAAGATAGCCGTGATGAGAACGATGTTGA
TTTGCAAAAATCAAATATCCTTATGATTGGCCCGACTGGTTCAGGAAAAACCTTCCTAGCTCAGACCTTGGCTAAAAGTT
TGAATGTCCCGTTTGCTATTGCCGATGCGACCGCTCTTACTGAGGCGGGTTATGTTGGTGAAGACGTAGAAAATATCCTC
CTCAAACTTTTGCAGGCTGCAGACTTTAACATTGACCGTGCAGAAAGAGGAATTATCTATGTGGATGAAATTGATAAAAT
TGCCAAAAAAGGTGAAAATGTGTCCATTACCCGCGATGTATCTGGTGAAGGTGTCCAGCAAGCTCTCCTAAAAATTATCG
AGGGAACTGTGGCCAGCGTACCACCACAAGGTGGACGCAAACATCCAAACCAAGAAATGATTCACGTGGACACCAAAAAT
ATCCTGTTTATCGTTGGCGGTGCATTTGATGGTATCGAAGAAATCGTCAAGCAGCGTCTCGGTGAAAAAATCATCGGTTT
TGGTCATAATAATCGTGCTATTGATGAAAAAGAATCATACATGCAACATATCATTGCAGACGATATTCAAAAATTCGGTA
TCATTCCAGAGTTGATTGGTCGCTTGCCTGTATTCGCAGCTTTGGACCAATTGACAACAGAGGATTTGGTACGCATTTTG
ACGGAACCGAAGAATGCTCTTGTAAAACAATACCAGACACTCTTGTCTTATGATGACGTGGAGCTTGACTTTGATGAGGA
CGCCTTGTTAGCAATTGCAGAAAAAGCAATTGAACGTAAAACTGGTGCTCGTGGACTTCGCTCCATCATTGAAGAAACGA
TGTTGGATGTCATGTTTGAGGTGCCAGGTCAAGATAACGTTAAACGCGTTCGTGTAACCAAAGCAGCAGTAGACGGTAAG
GAAAAGCCTTTACTAGAAACTGCATAA

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G7SE29

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

83.13

100

0.833
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.209

98.529

0.574

Multiple sequence alignment