Detailed information NTG0298441

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: DK876_RS07675
• Genome accession: NZ_CP030022
• Coordinates: 1564079..1565128 (-)
• Length: 349 a.a.
• NCBI ID: WP_012775295.1
• Uniprot ID: A0A2K1T047
• Organism: Streptococcus suis strain ISU2714
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1559079..1570128

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DK876_RS07655 (DK876_07935)	nadE	1559485..1560309 (+)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-
DK876_RS07660 (DK876_07940)	-	1561605..1562132 (-)	528	WP_012027591.1	VanZ family protein	-
DK876_RS07665 (DK876_07945)	rlmN	1562129..1563241 (-)	1113	WP_012028433.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
DK876_RS07670 (DK876_07950)	-	1563250..1563891 (-)	642	WP_012027595.1	YutD-like domain-containing protein	-
DK876_RS07675 (DK876_07955)	sepM	1564079..1565128 (-)	1050	WP_012775295.1	SepM family pheromone-processing serine protease	Regulator
DK876_RS07680 (DK876_07960)	coaD	1565115..1565603 (-)	489	WP_012027597.1	pantetheine-phosphate adenylyltransferase	-
DK876_RS07685 (DK876_07965)	rsmD	1565593..1566132 (-)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
DK876_RS07690 (DK876_07970)	-	1566440..1567162 (-)	723	WP_012027598.1	lipoprotein	-
DK876_RS07695 (DK876_07975)	-	1567219..1567605 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
DK876_RS07700 (DK876_07980)	-	1567605..1567823 (-)	219	WP_004194736.1	YqgQ family protein	-
DK876_RS07705 (DK876_07985)	-	1568131..1568733 (-)	603	WP_012027601.1	response regulator transcription factor	-
DK876_RS07710 (DK876_07990)	-	1568730..1569824 (-)	1095	WP_012027602.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37761.83 Da
• Isoelectric Point: 4.6112

>NTDB_id=298441 DK876_RS07675 WP_012775295.1 1564079..1565128(-) (sepM) [Streptococcus suis strain ISU2714]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=298441 DK876_RS07675 WP_012775295.1 1564079..1565128(-) (sepM) [Streptococcus suis strain ISU2714]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAGGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAGACATCGCAAAATATGGCGAAGTACCAAGGTTTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGGATAGGTATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAATCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A2K1T047

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605