Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ERO09_RS06560 Genome accession   NZ_CP035368
Coordinates   1343041..1344867 (-) Length   608 a.a.
NCBI ID   WP_070775790.1    Uniprot ID   -
Organism   Haemophilus parainfluenzae strain LC_1315_18     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1338041..1349867
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ERO09_RS06540 (ERO09_06540) - 1338545..1339543 (+) 999 WP_149785877.1 iron ABC transporter substrate-binding protein -
  ERO09_RS06545 (ERO09_06545) - 1339628..1341148 (+) 1521 WP_049370161.1 iron ABC transporter permease -
  ERO09_RS06550 (ERO09_06550) - 1341162..1342214 (+) 1053 WP_049370160.1 ABC transporter ATP-binding protein -
  ERO09_RS06555 (ERO09_06555) - 1342253..1342972 (-) 720 WP_049372408.1 TerC family protein -
  ERO09_RS06560 (ERO09_06560) uvrC 1343041..1344867 (-) 1827 WP_070775790.1 excinuclease ABC subunit UvrC Machinery gene
  ERO09_RS06565 (ERO09_06565) kdsB 1344877..1345635 (-) 759 WP_128787524.1 3-deoxy-manno-octulosonate cytidylyltransferase -
  ERO09_RS06570 (ERO09_06570) - 1345645..1345824 (-) 180 WP_049372406.1 Trm112 family protein -
  ERO09_RS06575 (ERO09_06575) lpxK 1345842..1346822 (-) 981 WP_128787525.1 tetraacyldisaccharide 4'-kinase -
  ERO09_RS06580 (ERO09_06580) msbA 1346876..1348639 (-) 1764 WP_128787526.1 lipid A ABC transporter ATP-binding protein/permease MsbA -

Sequence

Protein


Download         Length: 608 a.a.        Molecular weight: 69192.04 Da        Isoelectric Point: 9.0355

>NTDB_id=298401 ERO09_RS06560 WP_070775790.1 1343041..1344867(-) (uvrC) [Haemophilus parainfluenzae strain LC_1315_18]
MFDSKKFLSDVSHKPGVYRMYDDKDQVIYVGKAKDLKKRLSSYFRKNLSSKKTEALVSSIHHIDTTITSSETEALLLEHN
FIKLYQPRYNVLLRDDKSYPFILLTKERHPRITSYRGTKKIAGEYFGPYPHAGAVRETLSLMQKLFPVRQCENSVYNNRS
RPCLQYQIGRCSAPCVPGYVTDEEYNQQVELARLFLQGKDQQVLDYLIGKMEQASRDLDFEGAARYRDQIQAVRAVIEKQ
FVSNERLDDMDIMSIAYQHGLACVQVMFIRQGKVLGNRSYFPKVPANTDLSELTATFVGQFYLQGHQGRSIPNSIIVDHK
LDEKAELEALLTEQAGRKVVIQESAKGDKGKYLQLAQINAKAALATQLKQSSRMYERYQALCELLDMPEIKRMECFDISH
TMGNQTVASCVVFNQEGPLKSDYRRFNIEGITGGDDYAAMEQALKKRYDRDLDEDKIPDIIFIDGGKGQLNRALEVFHHL
NVKWDKNRPHLIGVAKGVDRRAGQEVLIISKQDREIHLPDDSLALHLIQHIRDESHNHAISGHRQKRQKAFTQSGLETIE
GVGAKRRQALLKYLGGLQGVKNATLDEIASVPGISKALAEKIFETLKS

Nucleotide


Download         Length: 1827 bp        

>NTDB_id=298401 ERO09_RS06560 WP_070775790.1 1343041..1344867(-) (uvrC) [Haemophilus parainfluenzae strain LC_1315_18]
ATGTTTGATTCTAAAAAGTTTCTCTCTGACGTTTCTCATAAACCTGGTGTTTATCGTATGTATGACGATAAAGATCAGGT
TATTTATGTGGGCAAAGCGAAAGATCTAAAAAAGCGCCTTTCCAGCTACTTCCGAAAAAACTTAAGCAGCAAAAAAACAG
AAGCCTTGGTGTCGTCAATTCATCATATTGATACGACGATTACTTCTTCAGAAACTGAAGCGTTATTGCTAGAGCACAAC
TTCATTAAGCTTTATCAACCTCGTTATAATGTGTTATTGCGAGATGATAAATCCTATCCTTTTATTTTATTGACAAAAGA
ACGCCATCCTCGCATTACTTCTTATCGCGGAACGAAAAAAATTGCAGGCGAGTATTTCGGGCCTTATCCTCATGCGGGTG
CAGTGCGTGAAACCTTGTCGTTAATGCAAAAATTATTCCCTGTTCGTCAATGTGAAAATTCGGTTTATAACAATCGTTCC
CGCCCTTGTTTGCAATATCAAATCGGGCGTTGCTCCGCACCTTGTGTGCCAGGCTATGTGACTGATGAGGAATATAACCA
ACAAGTTGAATTAGCACGACTATTTTTACAAGGAAAAGATCAGCAAGTATTAGATTATCTCATTGGCAAAATGGAGCAGG
CGAGCCGAGACTTGGATTTTGAAGGCGCGGCACGTTATCGTGACCAAATTCAAGCGGTTCGTGCTGTTATCGAAAAACAA
TTTGTTTCCAATGAGCGTTTGGATGACATGGATATTATGTCCATTGCGTATCAGCACGGTTTAGCTTGTGTTCAGGTAAT
GTTTATTCGTCAAGGCAAAGTATTGGGCAATCGCAGTTATTTTCCGAAAGTGCCTGCTAATACAGATTTATCTGAACTCA
CAGCCACTTTTGTTGGGCAGTTCTATTTGCAAGGTCATCAGGGCAGAAGTATTCCTAATAGTATTATTGTGGATCATAAA
TTAGATGAAAAAGCGGAGCTTGAGGCCTTATTAACTGAACAAGCCGGCCGAAAAGTGGTGATACAAGAATCTGCTAAAGG
CGATAAAGGCAAGTATTTGCAGTTGGCACAAATTAATGCCAAAGCGGCCTTAGCGACTCAACTTAAACAATCTTCCCGAA
TGTACGAACGTTATCAAGCGCTTTGTGAATTGCTCGATATGCCTGAAATTAAACGCATGGAATGTTTTGATATTAGTCAT
ACGATGGGTAATCAAACCGTGGCATCTTGCGTGGTATTTAATCAAGAAGGCCCACTGAAATCAGATTATCGCCGTTTTAA
TATTGAAGGTATTACGGGTGGTGATGATTATGCAGCGATGGAGCAAGCCTTAAAGAAACGTTACGACCGCGATCTTGATG
AAGATAAAATTCCCGATATTATTTTTATTGATGGTGGTAAAGGGCAGCTTAATCGTGCCTTAGAGGTTTTTCATCACCTC
AACGTAAAATGGGATAAAAACCGACCGCACTTAATTGGTGTTGCAAAAGGTGTAGATCGTCGAGCAGGACAAGAGGTGTT
GATTATCAGCAAACAAGATCGTGAAATCCATTTGCCGGATGATAGTCTTGCGTTGCATTTAATCCAACATATTCGAGATG
AAAGCCATAATCATGCGATTAGCGGTCATCGTCAAAAACGCCAAAAAGCCTTTACCCAAAGTGGATTGGAAACCATTGAA
GGGGTAGGTGCTAAACGACGTCAAGCCTTGTTGAAATATTTAGGTGGATTGCAAGGTGTCAAAAATGCCACGTTGGATGA
AATCGCCTCTGTACCCGGTATTTCTAAAGCGTTAGCAGAAAAGATTTTCGAGACCTTAAAAAGTTAG

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-90)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(384-540)

Helix-hairpin-helix domain (HHH_5)

(556-607)

UvrB/uvrC motif (UVR)

(210-235)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

37.96

98.355

0.373
  uvrC Streptococcus pneumoniae R6

37.625

98.355

0.37
  uvrC Streptococcus pneumoniae D39

37.625

98.355

0.37

Multiple sequence alignment