Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   A7J09_RS08655 Genome accession   NZ_CP030015
Coordinates   1786194..1786883 (-) Length   229 a.a.
NCBI ID   WP_012027645.1    Uniprot ID   -
Organism   Streptococcus suis strain ISU2812     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1781194..1791883
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7J09_RS08630 (A7J09_08800) - 1781338..1782051 (-) 714 WP_053861635.1 NADPH-dependent oxidoreductase -
  A7J09_RS08635 (A7J09_08805) dnaI 1782048..1782947 (-) 900 WP_029178689.1 primosomal protein DnaI -
  A7J09_RS08640 (A7J09_08810) - 1782947..1784098 (-) 1152 WP_029174426.1 replication initiation/membrane attachment protein -
  A7J09_RS08645 (A7J09_08815) nrdR 1784085..1784576 (-) 492 WP_029174427.1 transcriptional regulator NrdR -
  A7J09_RS08650 (A7J09_08820) - 1784648..1785778 (-) 1131 WP_029174428.1 AI-2E family transporter -
  A7J09_RS08655 (A7J09_08825) covR 1786194..1786883 (-) 690 WP_012027645.1 response regulator transcription factor Regulator
  A7J09_RS08660 (A7J09_08830) gndA 1786965..1788392 (-) 1428 WP_029175278.1 NADP-dependent phosphogluconate dehydrogenase -
  A7J09_RS08665 (A7J09_08835) - 1788480..1789019 (-) 540 WP_029175279.1 YceD family protein -
  A7J09_RS08670 (A7J09_08840) trxB 1789028..1789945 (-) 918 WP_029175280.1 thioredoxin-disulfide reductase -
  A7J09_RS08675 (A7J09_08845) - 1789959..1790195 (-) 237 WP_029174430.1 DUF4059 family protein -
  A7J09_RS08680 (A7J09_08850) - 1790213..1791556 (-) 1344 WP_029175281.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26255.14 Da        Isoelectric Point: 5.3968

>NTDB_id=298274 A7J09_RS08655 WP_012027645.1 1786194..1786883(-) (covR) [Streptococcus suis strain ISU2812]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHETDFDLILMSFQLSDMSSKELATELLAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=298274 A7J09_RS08655 WP_012027645.1 1786194..1786883(-) (covR) [Streptococcus suis strain ISU2812]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCCATGGAATTGCAGAAAAAAGACTA
TCTTGTTGATTATGCATCGACAGGGAAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGATTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGCAAGGAATTGGCTACAGAACTATTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACAGAAGTTAGTCAATATGGGGAAGAAGTCCTCTCTTATGCTGTTTCCTACGTAGTGAAGCCCTTTGTCAT
CAGTGATTTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGATTTTATTGACAATAATTGTAAACAGGTTCACATGC
ATGCGGCCTATCGTGATTTGAAGGTTGATTTTCAAAATCGAACAGTGACTCGAGGTGATGAATTGATTAATTTGACCCGC
CGAGAGTATGATCTGCTGGCTACCTTAATGAACAGTCCAGAACCTGTTAGTCGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATAAAAACAGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432

Multiple sequence alignment