Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   EQH15_RS07580 Genome accession   NZ_CP035265
Coordinates   1487821..1488498 (-) Length   225 a.a.
NCBI ID   WP_000548991.1    Uniprot ID   A0A501PEF7
Organism   Streptococcus pneumoniae strain TVO_1901920     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1482821..1493498
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH15_RS07550 (EQH15_07915) - 1482982..1483611 (-) 630 WP_000762089.1 NAD(P)-dependent oxidoreductase -
  EQH15_RS07555 - 1483850..1484224 (+) 375 Protein_1514 hypothetical protein -
  EQH15_RS07560 (EQH15_07930) - 1484481..1484621 (+) 141 WP_000422775.1 MazG-like protein -
  EQH15_RS07565 (EQH15_07935) - 1484628..1484804 (+) 177 WP_000166031.1 MazG-like protein -
  EQH15_RS07570 (EQH15_07940) thrS 1484862..1486805 (+) 1944 WP_000608349.1 threonine--tRNA ligase -
  EQH15_RS07575 (EQH15_07945) - 1486854..1487828 (-) 975 WP_000887953.1 HAMP domain-containing histidine kinase -
  EQH15_RS07580 (EQH15_07950) braR 1487821..1488498 (-) 678 WP_000548991.1 response regulator transcription factor Regulator
  EQH15_RS07585 (EQH15_07955) - 1488654..1489727 (+) 1074 WP_001273834.1 DUF2974 domain-containing protein -
  EQH15_RS07590 (EQH15_07960) - 1489818..1490120 (-) 303 WP_000281608.1 hypothetical protein -
  EQH15_RS07595 (EQH15_07965) - 1490188..1490625 (-) 438 WP_001166786.1 Rrf2 family transcriptional regulator -
  EQH15_RS07600 (EQH15_07970) - 1490701..1491543 (-) 843 WP_000160943.1 metallophosphoesterase -
  EQH15_RS07605 (EQH15_07975) - 1491655..1492305 (+) 651 WP_000188498.1 metal-dependent transcriptional regulator -
  EQH15_RS07610 (EQH15_07985) - 1492504..1493181 (+) 678 WP_000260186.1 nicotinamide mononucleotide transporter -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25936.11 Da        Isoelectric Point: 5.1362

>NTDB_id=298048 EQH15_RS07580 WP_000548991.1 1487821..1488498(-) (braR) [Streptococcus pneumoniae strain TVO_1901920]
MHKILLVEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=298048 EQH15_RS07580 WP_000548991.1 1487821..1488498(-) (braR) [Streptococcus pneumoniae strain TVO_1901920]
ATGCACAAGATTTTATTAGTGGAAGATGATCAGGTCATTCGTCAACAGGTTGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCGGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCTAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAACGAATTCCAGATTTTA
CGCGTGTTATTTGAGCATGCAGGCAACATCGTAGCACGTGACGACCTGATGCGGGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A501PEF7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

49.083

96.889

0.476
  vicR Streptococcus mutans UA159

35.319

100

0.369