Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   EQH16_RS02275 Genome accession   NZ_CP035264
Coordinates   414109..414741 (+) Length   210 a.a.
NCBI ID   WP_000698429.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901921     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 409109..419741
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH16_RS02250 (EQH16_02325) mvaD 409386..410339 (+) 954 WP_000373461.1 diphosphomevalonate decarboxylase -
  EQH16_RS02255 (EQH16_02330) - 410326..411333 (+) 1008 WP_000562419.1 phosphomevalonate kinase -
  EQH16_RS02260 (EQH16_02335) fni 411317..412327 (+) 1011 WP_000210629.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  EQH16_RS02265 (EQH16_02340) liaF 412405..413103 (+) 699 WP_001224634.1 cell wall-active antibiotics response protein LiaF -
  EQH16_RS02270 (EQH16_02345) - 413100..414095 (+) 996 WP_000743661.1 sensor histidine kinase -
  EQH16_RS02275 (EQH16_02350) vraR 414109..414741 (+) 633 WP_000698429.1 response regulator transcription factor Regulator
  EQH16_RS02280 - 414817..415511 (+) 695 Protein_448 DNA alkylation repair protein -
  EQH16_RS02285 (EQH16_02370) - 415661..415900 (+) 240 WP_000754502.1 hypothetical protein -
  EQH16_RS02290 (EQH16_02375) cbpG 415981..416802 (+) 822 WP_001100132.1 choline-binding protein CbpG -
  EQH16_RS02295 (EQH16_02380) cbpF 416821..417843 (+) 1023 WP_000771075.1 choline-binding protein CbpF -
  EQH16_RS02300 (EQH16_02385) - 417971..419319 (-) 1349 Protein_452 IS3 family transposase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23535.00 Da        Isoelectric Point: 4.5791

>NTDB_id=297883 EQH16_RS02275 WP_000698429.1 414109..414741(+) (vraR) [Streptococcus pneumoniae strain TVO_1901921]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKILPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=297883 EQH16_RS02275 WP_000698429.1 414109..414741(+) (vraR) [Streptococcus pneumoniae strain TVO_1901921]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGATTGGGCTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCCTGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAATATTCTTGCCAAACT
TGAAGTCAGCGATCGTACCCAGGCGGCTGTCTATGCCTTTCAGCACCATTTGGTGGGGCAAGAGGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41