Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   EQH17_RS02750 Genome accession   NZ_CP035263
Coordinates   555412..557256 (+) Length   614 a.a.
NCBI ID   WP_001061152.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901922     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 550412..562256
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH17_RS02730 (EQH17_02925) - 551244..552023 (+) 780 WP_000290013.1 alpha/beta hydrolase family protein -
  EQH17_RS02735 (EQH17_02930) murM 552135..553355 (+) 1221 WP_000286563.1 peptidoglycan bridge formation alanyltransferase MurM -
  EQH17_RS02740 (EQH17_02935) murN 553360..554592 (+) 1233 WP_001229511.1 peptidoglycan bridge formation alanyltransferase MurN -
  EQH17_RS02745 (EQH17_02940) - 554671..555372 (+) 702 WP_001267410.1 M57 family metalloprotease -
  EQH17_RS02750 (EQH17_02945) uvrC 555412..557256 (+) 1845 WP_001061152.1 excinuclease ABC subunit UvrC Machinery gene
  EQH17_RS02755 (EQH17_02950) - 557246..558079 (+) 834 WP_001015779.1 metallophosphoesterase -
  EQH17_RS02760 (EQH17_02955) - 558261..559061 (-) 801 WP_000714634.1 amino acid ABC transporter substrate-binding protein -
  EQH17_RS02765 (EQH17_02960) - 559232..559837 (+) 606 WP_000670173.1 nitroreductase family protein -
  EQH17_RS02770 (EQH17_02965) pepV 559850..561250 (+) 1401 WP_000125045.1 dipeptidase PepV -
  EQH17_RS02775 (EQH17_02970) - 561304..561882 (+) 579 WP_000078149.1 uracil-DNA glycosylase family protein -

Sequence

Protein


Download         Length: 614 a.a.        Molecular weight: 70421.99 Da        Isoelectric Point: 9.2183

>NTDB_id=297772 EQH17_RS02750 WP_001061152.1 555412..557256(+) (uvrC) [Streptococcus pneumoniae strain TVO_1901922]
MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSYFRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEIN
LIKENKPKYNIMLKDDKSYPFIKITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
YYHIGQCMAHTICKKDETYFKSMAQEVSDFLKGQDNKIIDELKGKMAAAAQTMEFERAAEYRDLIQAIGTLRTKQRVMAK
DLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNLFPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKAL
VDTKILKPQRGEKKQLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGTSPVSAMVV
FVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLIVIDGGQGQVNIAKQVIQEELGLDIPIAGLQ
KNDKHQTHELLFGDPLEVVDLSRNSQEFFLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSL
TKIKEASVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP

Nucleotide


Download         Length: 1845 bp        

>NTDB_id=297772 EQH17_RS02750 WP_001061152.1 555412..557256(+) (uvrC) [Streptococcus pneumoniae strain TVO_1901922]
ATGAACAACTTGATTAAATCAAAACTAGAGCTCTTGCCGACCAGCCCTGGTTGCTACATTCATAAGGATAAAAATGGCAC
CATTATCTATGTAGGAAAGGCTAAAAATCTGCGTAATCGAGTACGGTCCTATTTTCGTGGAAGTCATGATACCAAGACAG
AGGCTCTGGTGTCTGAAATTGTGGATTTTGAATTTATTGTTACGGAGTCTAATATTGAGGCACTTCTCCTAGAAATCAAC
CTGATCAAGGAAAACAAGCCCAAGTACAATATCATGCTCAAGGATGACAAGTCCTATCCTTTCATCAAAATCACCAATGA
GCGCTATCCACGCTTGATTATCACTCGTCAGGTCAAAAAGGACGGAGGTCTTTATTTTGGACCCTATCCCGATGTGGGGG
CAGCCAATGAAATCAAGCGGTTGCTGGATCGGATATTCCCTTTTCGTAAGTGTACCAACCCGCCCTCTAAGGTCTGTTTT
TATTACCATATCGGTCAATGCATGGCCCACACCATCTGTAAGAAGGATGAGACTTATTTCAAGTCTATGGCCCAGGAGGT
TTCTGATTTTCTGAAAGGGCAGGATAACAAAATCATTGATGAGCTAAAGGGCAAAATGGCAGCGGCAGCCCAGACTATGG
AGTTTGAACGTGCGGCGGAATACCGTGACCTGATTCAGGCTATTGGAACGCTTCGAACCAAGCAACGGGTCATGGCTAAG
GATCTCCAAAATCGCGATGTCTTTGGCTACTATGTGGATAAGGGCTGGATGTGTGTGCAGGTTTTCTTTGTCCGTCAGGG
TAAGCTCATCGAGCGCGATGTCAATCTCTTCCCCTACTTCAATGATCCAGATGAGGATTTTTTGACCTATGTAGGACAAT
TCTATCAAGAAAAATCTCACCTAGTTCCCAATGAGGTACTGATTCCGCAGGATATTGACGAAGAGGCTGTCAAGGCTTTG
GTGGATACCAAGATTCTCAAACCCCAACGTGGAGAGAAAAAACAGCTGGTCAATCTAGCCATAAAAAATGCACGTGTTAG
TCTGGAGCAGAAATTTAACCTGCTAGAGAAATCTGTCGAGAAGACCCAAGGAGCTATTGAAAATCTAGGACGTTTGCTCC
AAATCCCGACCCCAGTACGTATCGAGTCCTTCGATAACTCTAATATCATGGGAACTAGCCCTGTTTCGGCTATGGTGGTC
TTTGTCAACGGTAAACCGAGTAAGAAGGATTACCGTAAGTACAAGATAAAAACGGTTGTTGGACCAGACGACTATGCCAG
CATGAGAGAGGTCATTCGCAGACGCTATGGTCGAGTACAGCGTGAGGCTTTGACTCCTCCAGATTTGATTGTGATTGATG
GGGGGCAAGGTCAAGTCAATATCGCTAAGCAGGTTATCCAAGAGGAACTGGGCTTGGATATTCCAATTGCTGGGCTGCAA
AAGAATGATAAGCACCAAACCCATGAATTGCTCTTTGGAGATCCGCTTGAGGTGGTGGACTTGTCTCGCAATTCTCAGGA
ATTTTTCCTCCTCCAACGCATCCAAGATGAGGTGCACCGCTTTGCCATTACCTTCCACCGCCAACTGCGCTCCAAAAATT
CTTTCTCATCTCAATTGGATGGGATTGACGGTCTGGGACCTAAACGCAAGCAGAATCTTATGAAGCATTTCAAGTCTTTG
ACCAAAATCAAGGAAGCCAGTGTGGATGAGATTGTCGAAGTTGGGGTACCTAGAGTCGTTGCAGAGGCTGTGCAAAGAAA
GTTGAACCCGCAGGGAGAAGCCTTGCCTCAAGTAGCAGAAGAAAGAGTAGATTACCAAACGGAAGGAAACCACAATGAAC
CATAA

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(17-90)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)

UvrB/uvrC motif (UVR)

(197-228)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

98.86

100

0.989
  uvrC Streptococcus pneumoniae R6

98.371

100

0.984
  uvrC Streptococcus pneumoniae D39

98.371

100

0.984