Detailed information NTG0297481

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: EQH20_RS08760
• Genome accession: NZ_CP035260
• Coordinates: 1732374..1733273 (-)
• Length: 299 a.a.
• NCBI ID: WP_000904867.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901925
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1727374..1738273

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH20_RS08735 (EQH20_09235)	rsmA	1727704..1728576 (-)	873	WP_001216856.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
EQH20_RS08740 (EQH20_09240)	-	1728707..1729015 (-)	309	WP_000333257.1	hypothetical protein	-
EQH20_RS08745 (EQH20_09245)	-	1729008..1729649 (-)	642	WP_050137387.1	ABC transporter ATP-binding protein	-
EQH20_RS08750 (EQH20_09250)	-	1729651..1731681 (-)	2031	WP_000825263.1	bacteriocin-associated integral membrane family protein	-
EQH20_RS08755 (EQH20_09255)	-	1731758..1732054 (-)	297	WP_000815394.1	lactococcin 972 family bacteriocin	-
EQH20_RS08760 (EQH20_09260)	comR	1732374..1733273 (-)	900	WP_000904867.1	helix-turn-helix domain-containing protein	Regulator
EQH20_RS08765 (EQH20_09265)	rnmV	1733345..1733905 (-)	561	WP_000664448.1	ribonuclease M5	-
EQH20_RS08770 (EQH20_09270)	-	1733905..1734678 (-)	774	WP_000575607.1	TatD family hydrolase	-
EQH20_RS08775 (EQH20_09280)	-	1734984..1735703 (-)	720	Protein_1730	DUF1542 domain-containing protein	-
EQH20_RS08780 (EQH20_09285)	-	1735984..1737240 (+)	1257	WP_238124923.1	ISL3-like element IS1167A family transposase	-
EQH20_RS08785 (EQH20_09290)	rpmH	1737333..1737467 (-)	135	WP_000831905.1	50S ribosomal protein L34	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35191.04 Da
• Isoelectric Point: 5.0703

>NTDB_id=297481 EQH20_RS08760 WP_000904867.1 1732374..1733273(-) (comR) [Streptococcus pneumoniae strain TVO_1901925]
MLIGQKIKEIRIEKGISRPDFCGDEQGLTVRQLSRIESGASQPSLPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAKLIGDGFLVKKLTEEWQEDVKKYL

Nucleotide

• Length: 900 bp

>NTDB_id=297481 EQH20_RS08760 WP_000904867.1 1732374..1733273(-) (comR) [Streptococcus pneumoniae strain TVO_1901925]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGG
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGCCTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTTCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGCCTCAGATTATAGAAAAAGAAGCTTATTCAATAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTCTT
TCTTTTGGAACAGAAGAAGGTAACTCAAATAGAGAATTACTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGTAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGAAGCTAATTGGAGATGGATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (7-59)

• ComR tetratricopeptide (ComR_TPR) (70-291)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	37.755	98.328	0.371
comR	Streptococcus suis P1/7	37.801	97.324	0.368
comR	Streptococcus suis 05ZYH33	37.801	97.324	0.368