Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   EQH21_RS01915 Genome accession   NZ_CP035259
Coordinates   367896..368528 (+) Length   210 a.a.
NCBI ID   WP_000698432.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901926     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 362896..373528
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH21_RS01890 (EQH21_01995) mvaD 363174..364127 (+) 954 WP_000373457.1 diphosphomevalonate decarboxylase -
  EQH21_RS01895 (EQH21_02000) - 364114..365121 (+) 1008 WP_000562432.1 phosphomevalonate kinase -
  EQH21_RS01900 (EQH21_02005) fni 365105..366115 (+) 1011 WP_000210614.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  EQH21_RS01905 (EQH21_02010) liaF 366192..366890 (+) 699 WP_001224637.1 cell wall-active antibiotics response protein LiaF -
  EQH21_RS01910 (EQH21_02015) - 366887..367882 (+) 996 WP_000743659.1 sensor histidine kinase -
  EQH21_RS01915 (EQH21_02020) vraR 367896..368528 (+) 633 WP_000698432.1 response regulator transcription factor Regulator
  EQH21_RS01920 - 368604..369287 (+) 684 Protein_381 DNA alkylation repair protein -
  EQH21_RS01925 (EQH21_02040) - 369437..369661 (+) 225 Protein_382 hypothetical protein -
  EQH21_RS01930 (EQH21_02045) - 369805..371151 (+) 1347 WP_001808790.1 IS1380-like element ISSpn5 family transposase -
  EQH21_RS01935 (EQH21_02050) - 371454..372056 (+) 603 Protein_384 trypsin-like serine peptidase -
  EQH21_RS01940 (EQH21_02055) - 372412..372717 (+) 306 WP_000889974.1 tyrosine-type recombinase/integrase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23562.04 Da        Isoelectric Point: 4.6491

>NTDB_id=297294 EQH21_RS01915 WP_000698432.1 367896..368528(+) (vraR) [Streptococcus pneumoniae strain TVO_1901926]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGHEEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=297294 EQH21_RS01915 WP_000698432.1 367896..368528(+) (vraR) [Streptococcus pneumoniae strain TVO_1901926]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGATTGGGCTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAACATTCTTGCCAAACT
TGAAGTTAGCGATCGTACCCAGGCGGCTGTCTATGCCTTTCAGCACCATTTGGTGGGGCATGAGGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41