Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   EQH22_RS07440 Genome accession   NZ_CP035258
Coordinates   1491894..1492571 (-) Length   225 a.a.
NCBI ID   WP_000548959.1    Uniprot ID   Q9S1K2
Organism   Streptococcus pneumoniae strain TVO_1901927     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1486894..1497571
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH22_RS07415 (EQH22_07785) - 1487056..1487685 (-) 630 WP_000762094.1 NAD(P)-dependent oxidoreductase -
  EQH22_RS07420 (EQH22_07790) - 1487923..1488123 (+) 201 WP_001826938.1 hypothetical protein -
  EQH22_RS07425 (EQH22_07805) - 1488554..1488877 (+) 324 WP_000422781.1 hypothetical protein -
  EQH22_RS07430 (EQH22_07810) thrS 1488935..1490878 (+) 1944 WP_000608358.1 threonine--tRNA ligase -
  EQH22_RS07435 (EQH22_07815) - 1490927..1491901 (-) 975 WP_000887954.1 HAMP domain-containing histidine kinase -
  EQH22_RS07440 (EQH22_07820) braR 1491894..1492571 (-) 678 WP_000548959.1 response regulator transcription factor Regulator
  EQH22_RS07445 (EQH22_07825) - 1492727..1493800 (+) 1074 WP_001273825.1 DUF2974 domain-containing protein -
  EQH22_RS07450 (EQH22_07830) - 1494081..1495427 (+) 1347 WP_001811769.1 IS1380-like element ISSpn5 family transposase -
  EQH22_RS07455 (EQH22_07835) - 1495590..1495901 (-) 312 WP_054362888.1 hypothetical protein -
  EQH22_RS07460 (EQH22_07840) - 1495970..1496407 (-) 438 WP_001166786.1 Rrf2 family transcriptional regulator -
  EQH22_RS07465 (EQH22_07845) - 1496483..1497325 (-) 843 WP_000160944.1 metallophosphoesterase -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25964.16 Da        Isoelectric Point: 5.1362

>NTDB_id=297220 EQH22_RS07440 WP_000548959.1 1491894..1492571(-) (braR) [Streptococcus pneumoniae strain TVO_1901927]
MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=297220 EQH22_RS07440 WP_000548959.1 1491894..1492571(-) (braR) [Streptococcus pneumoniae strain TVO_1901927]
ATGCACAAGATTTTATTAATAGAAGATGATCAGGTCATTCGTCAACAGATTGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCGGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCTAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAATGAATTCCAGATTTTA
CGCGTGTTATTTGAGCATGCAGGCAACATCGTAGCACGTGACGACCTGATGCGGGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9S1K2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

48.624

96.889

0.471
  vicR Streptococcus mutans UA159

35.319

100

0.369