Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   SUB_RS06945 Genome accession   NC_012004
Coordinates   1378045..1378686 (-) Length   213 a.a.
NCBI ID   WP_015911702.1    Uniprot ID   B9DV39
Organism   Streptococcus uberis 0140J     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1373045..1383686
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SUB_RS06920 (SUB1377) comFA/cflA 1373212..1374513 (-) 1302 WP_015911697.1 DEAD/DEAH box helicase Machinery gene
  SUB_RS06925 (SUB1378) - 1374570..1375199 (+) 630 WP_015911698.1 YigZ family protein -
  SUB_RS06930 (SUB1379) cysK 1375308..1376240 (+) 933 WP_015911699.1 cysteine synthase A -
  SUB_RS06935 (SUB1380) - 1376255..1376611 (-) 357 WP_015911700.1 S1 RNA-binding domain-containing protein -
  SUB_RS06940 (SUB1381) - 1376611..1378011 (-) 1401 WP_037593423.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  SUB_RS06945 (SUB1382) vraR 1378045..1378686 (-) 642 WP_015911702.1 response regulator transcription factor Regulator
  SUB_RS06950 (SUB1383) - 1378679..1379683 (-) 1005 WP_015911703.1 sensor histidine kinase -
  SUB_RS06955 (SUB1384) liaF 1379680..1380375 (-) 696 WP_015911704.1 cell wall-active antibiotics response protein LiaF -
  SUB_RS06960 (SUB1385) pknB 1380493..1382379 (-) 1887 WP_015911705.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  SUB_RS06965 (SUB1386) - 1382376..1383116 (-) 741 WP_015911706.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23948.71 Da        Isoelectric Point: 4.8996

>NTDB_id=29696 SUB_RS06945 WP_015911702.1 1378045..1378686(-) (vraR) [Streptococcus uberis 0140J]
MDKIKVILVDDHEMVRLGLKSFLNMQKDVEVIAEASNGRQGIELALELKPDVLVMDLVMPELGGVEATLEILKEWPEAKI
LVLTSYLDNEKIYPVIDAGAKGYMLKTSSAAEILNAIQKVAKGQLAIETEVDKKIKAHDRKPNLHDELTAREYDILYLLA
KGYDNQTIADELFISLKTVKTHVSNILSKLEVDDRTQAVVYAFRHHLVPQDDN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=29696 SUB_RS06945 WP_015911702.1 1378045..1378686(-) (vraR) [Streptococcus uberis 0140J]
ATGGATAAAATAAAAGTGATACTTGTTGATGATCATGAGATGGTTCGGTTAGGTTTAAAAAGTTTCCTGAACATGCAAAA
AGATGTTGAAGTTATTGCTGAAGCATCCAATGGAAGACAGGGAATCGAATTGGCATTAGAGCTAAAGCCAGATGTTTTAG
TCATGGATCTGGTCATGCCAGAATTAGGTGGTGTTGAAGCAACCTTAGAAATATTAAAAGAGTGGCCTGAGGCTAAAATC
TTAGTCTTGACGTCATACCTTGATAATGAAAAAATATACCCTGTCATTGATGCGGGAGCCAAGGGTTATATGTTGAAAAC
ATCAAGTGCCGCTGAAATATTAAATGCTATTCAAAAAGTTGCTAAAGGTCAGCTAGCTATTGAGACAGAAGTCGATAAGA
AAATAAAGGCTCATGACAGAAAACCAAATTTACATGATGAATTAACTGCAAGAGAGTATGATATTCTCTACCTGTTAGCA
AAGGGTTATGATAATCAAACCATTGCTGATGAACTGTTTATATCATTAAAAACAGTCAAAACACACGTCTCCAATATCTT
GTCCAAATTAGAAGTCGACGATCGAACACAAGCAGTCGTCTATGCTTTCAGACACCACTTAGTGCCACAAGATGATAATT
AA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B9DV39

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

51.456

96.714

0.498
  degU Bacillus subtilis subsp. subtilis str. 168

36.842

100

0.394

Multiple sequence alignment