Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   EQH28_RS07355 Genome accession   NZ_CP035252
Coordinates   1460020..1461252 (-) Length   410 a.a.
NCBI ID   WP_000106346.1    Uniprot ID   P63791
Organism   Streptococcus pneumoniae strain TVO_1901934     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1455020..1466252
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH28_RS07330 (EQH28_07755) whiA 1456209..1457120 (-) 912 WP_000011293.1 DNA-binding protein WhiA -
  EQH28_RS07335 (EQH28_07760) - 1457117..1458094 (-) 978 WP_001231086.1 YvcK family protein -
  EQH28_RS07340 (EQH28_07765) rapZ 1458091..1458981 (-) 891 WP_000163031.1 RNase adapter RapZ -
  EQH28_RS07345 (EQH28_07770) - 1459033..1459413 (-) 381 WP_001140412.1 RidA family protein -
  EQH28_RS07350 (EQH28_07775) yihA 1459424..1460011 (-) 588 WP_000422599.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  EQH28_RS07355 (EQH28_07780) clpX 1460020..1461252 (-) 1233 WP_000106346.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  EQH28_RS07360 (EQH28_07785) - 1461284..1461454 (-) 171 WP_000442275.1 hypothetical protein -
  EQH28_RS07365 (EQH28_07790) - 1461454..1461960 (-) 507 WP_000162503.1 dihydrofolate reductase -
  EQH28_RS07370 (EQH28_07795) - 1462090..1462608 (-) 519 WP_000229874.1 DNA starvation/stationary phase protection protein -
  EQH28_RS07375 (EQH28_07800) lytC 1463104..1464609 (-) 1506 WP_075271359.1 choline binding-anchored murein hydrolase LytC -
  EQH28_RS07380 (EQH28_07805) tpiA 1464647..1465405 (-) 759 WP_000087897.1 triose-phosphate isomerase -
  EQH28_RS07385 (EQH28_07810) - 1465503..1466180 (-) 678 WP_000221604.1 DnaD domain-containing protein -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45798.35 Da        Isoelectric Point: 4.4550

>NTDB_id=296723 EQH28_RS07355 WP_000106346.1 1460020..1461252(-) (clpX) [Streptococcus pneumoniae strain TVO_1901934]
MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVD
GTDKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=296723 EQH28_RS07355 WP_000106346.1 1460020..1461252(-) (clpX) [Streptococcus pneumoniae strain TVO_1901934]
ATGTCTACAAATAGAAAAAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAACCAAGAAGAAGTACAAAAAATAAT
TGCTGGCAACAATGCTTTTATTTGTAATGAATGCGTGGAGTTAGCTCAGGAAATCATTCGAGAAGAATTGGTTGAGGAAG
TCTTGGCAGACTTGTCTGAGGTGCCAAAACCAATTGAACTCCTCCATATCTTGAACCACTATGTAATTGGTCAAGATCGT
GCCAAGCGTGCCTTGGCAGTGGCGGTTTATAATCACTACAAACGCATCAATTTCCACGATACACGCGAAGAGTCAGAAGA
TGTGGATTTGCAGAAGTCAAACATTTTGATGATTGGCCCAACTGGTTCAGGGAAAACTTTCCTTGCCCAGACCTTGGCTA
AGAGCTTGAATGTGCCTTTTGCTATTGCGGATGCGACAGCTCTGACGGAGGCTGGTTATGTGGGTGAGGATGTGGAAAAT
ATCCTCCTCAAACTCTTGCAGGTTGCTGACTTTAACATCGAACGTGCAGAGCGTGGCATTATCTATGTGGATGAAATTGA
CAAGATTGCCAAGAAGAGTGAGAATGTGTCTATCACACGTGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTCAAGA
TTATCGAGGGAACTGTTGCTAGCGTGCCGCCTCAAGGTGGACGCAAACATCCACAACAAGAGATGATTCAAGTGGATACA
AAAAATATCCTCTTCATCGTGGGTGGTGCTTTTGATGGTATTGAAGAAATTGTCAAACAACGTCTGGGTGAAAAAGTCAT
CGGATTTGGTCAAAACAATAAGGCGATTGACGAAAACAGCTCATACATGCAAGAAATCATCGCTGAAGACATTCAAAAAT
TTGGTATTATCCCTGAGTTGATTGGACGCTTGCCTGTTTTTGCGGCTCTTGAGCAATTGACCGTTGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTGAAACAATACCAAACCTTGCTTTCTTATGATGATGTTGAGTTGGAATTTGA
CGACGAAGCCCTTCAAGAGATTGCTAATAAAGCAATCGAACGGAAGACAGGGGCGCGTGGACTTCGCTCCATTATCGAAG
AAACCATGCTAGATGTTATGTTTGAGGTGCCGAGTCAGGAAAATGTGAAATTGGTTCGCATCACTAAAGAAACTGTTGAT
GGAACGGATAAACCGATCCTAGAAACAGCCTAG

Domains

Predicted by InterProScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P63791

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

86.585

100

0.866
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.214

98.049

0.561