Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   NMCC_RS09550 Genome accession   NC_010120
Coordinates   1857960..1858820 (+) Length   286 a.a.
NCBI ID   WP_002226036.1    Uniprot ID   A0A112F5U3
Organism   Neisseria meningitidis 053442     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1852960..1863820
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMCC_RS09530 (NMCC_1808) dapD 1853421..1854242 (-) 822 WP_002220281.1 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase -
  NMCC_RS09540 (NMCC_1809) pgi 1854452..1856144 (-) 1693 Protein_1778 glucose-6-phosphate isomerase -
  NMCC_RS09545 (NMCC_1810) pilG 1856654..1857886 (+) 1233 WP_002216405.1 type 4 pilus assembly protein PilG Machinery gene
  NMCC_RS09550 (NMCC_1811) pilD 1857960..1858820 (+) 861 WP_002226036.1 prepilin peptidase Machinery gene
  NMCC_RS09555 (NMCC_1812) coaE 1858822..1859454 (+) 633 WP_002245856.1 dephospho-CoA kinase -
  NMCC_RS09560 (NMCC_1813) yacG 1859447..1859656 (+) 210 WP_012222034.1 DNA gyrase inhibitor YacG -
  NMCC_RS09565 (NMCC_1814) pilF 1859741..1861417 (-) 1677 WP_002221967.1 type IV-A pilus assembly ATPase PilB Machinery gene
  NMCC_RS09575 (NMCC_1816) - 1861909..1862355 (-) 447 WP_012222035.1 DUF441 domain-containing protein -
  NMCC_RS09580 (NMCC_1817) ispB 1862360..1863334 (-) 975 WP_002216396.1 octaprenyl diphosphate synthase -

Sequence

Protein


Download         Length: 286 a.a.        Molecular weight: 31389.43 Da        Isoelectric Point: 8.2213

>NTDB_id=29668 NMCC_RS09550 WP_002226036.1 1857960..1858820(+) (pilD) [Neisseria meningitidis 053442]
MSDLSVLSPFAVPLTAVFGLLVGSFLNVVIYRVPVMMERGWTVFAKEYLNLPLTEEESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWSWITLGGLILTAFLISLTFIDADTQYLPDSMTLP
LIWLGLIFNLDGGFVPLQSAVLGAVAGYGSIWLLCAVYKLIKGEIGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGQHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVL

Nucleotide


Download         Length: 861 bp        

>NTDB_id=29668 NMCC_RS09550 WP_002226036.1 1857960..1858820(+) (pilD) [Neisseria meningitidis 053442]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGACAGCGGTGTTCGGGCTGCTGGTCGGAAGTTTCTTAAA
TGTCGTCATTTACCGCGTGCCGGTCATGATGGAACGCGGCTGGACGGTATTTGCCAAAGAATATTTAAACCTGCCGCTGA
CCGAAGAGGAAAGCCGTACCTTCAACCTGATGAAACCGGATTCCTGCTGTCCCAAATGCCGCGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGCTACCTGCTCCTGCGCGGCAAATGCGCCTCCTGCCAAACCAAAATCAGCATACGCTATCC
CTTAATCGAACTGCTGACCGGCGTATTGTTCGGGCTGGTTGCCTGGCAATACGGCTGGTCTTGGATTACATTGGGCGGTT
TGATACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACATTACCC
TTGATTTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATGGTTCGATATGGCTTTTATGCGCGGTATATAAACTGATTAAAGGCGAAATCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCGCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCAGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGCTGTAA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(17-124)

Type IV leader peptidase family (Peptidase_A24)

(134-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A112F5U3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Neisseria gonorrhoeae MS11

95.789

99.65

0.955
  pilD Vibrio cholerae strain A1552

44.097

100

0.444
  pilD Acinetobacter baumannii D1279779

46.97

92.308

0.434
  pilD Acinetobacter nosocomialis M2

46.97

92.308

0.434
  pilD Vibrio campbellii strain DS40M4

44.565

96.503

0.43

Multiple sequence alignment