Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   NMCC_RS08220 Genome accession   NC_010120
Coordinates   1590328..1590792 (-) Length   154 a.a.
NCBI ID   WP_162466967.1    Uniprot ID   -
Organism   Neisseria meningitidis 053442     
Function   DNA binding (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1582315..1590627 1590328..1590792 flank -299


Gene organization within MGE regions


Location: 1582315..1590792
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMCC_RS08170 - 1582315..1582548 (-) 234 Protein_1526 Lrp/AsnC ligand binding domain-containing protein -
  NMCC_RS08175 - 1582735..1582965 (-) 231 Protein_1527 Lrp/AsnC family transcriptional regulator -
  NMCC_RS08180 (NMCC_1552) alr 1583190..1584248 (+) 1059 WP_017629137.1 alanine racemase -
  NMCC_RS08185 (NMCC_1553) - 1584428..1585099 (-) 672 Protein_1529 IS1595 family transposase -
  NMCC_RS08190 (NMCC_1554) - 1585242..1586597 (-) 1356 WP_012221915.1 PFL family protein -
  NMCC_RS08195 (NMCC_1555) - 1586612..1586884 (-) 273 WP_002218494.1 ACT domain-containing protein -
  NMCC_RS08200 (NMCC_1556) - 1587010..1587747 (-) 738 WP_002223538.1 toxin-antitoxin system YwqK family antitoxin -
  NMCC_RS08205 (NMCC_1558) prmB 1588028..1588927 (-) 900 WP_025462038.1 50S ribosomal protein L3 N(5)-glutamine methyltransferase -
  NMCC_RS08210 (NMCC_1559) - 1589072..1589665 (+) 594 WP_012221918.1 hypothetical protein -
  NMCC_RS08215 (NMCC_1560) - 1589777..1590214 (+) 438 Protein_1535 HK97 family phage prohead protease -
  NMCC_RS08220 comE 1590328..1590792 (-) 465 WP_162466967.1 ComEA family DNA-binding protein Machinery gene

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 16487.81 Da        Isoelectric Point: 10.9077

>NTDB_id=29662 NMCC_RS08220 WP_162466967.1 1590328..1590792(-) (comE) [Neisseria meningitidis 053442]
MLCPEKMSGMAGRHPYGVRSGLRRNGLKLWDIHFKMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASQQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKGPAKPVLPAVKK

Nucleotide


Download         Length: 465 bp        

>NTDB_id=29662 NMCC_RS08220 WP_162466967.1 1590328..1590792(-) (comE) [Neisseria meningitidis 053442]
TTGCTTTGCCCGGAAAAAATGTCGGGGATGGCGGGACGGCATCCGTACGGCGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAAAATGACTCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCAGCAGGAGTTGGAGGCGCTGCCGGGCATAGGCCCTGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTGGACGATTTGACCAAGGTAAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGG
CTTCGGTCGGCGCGCCCGCACCAAAAGGCCCAGCTAAACCAGTGCTGCCCGCAGTGAAAAAATAG

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(75-133)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Neisseria gonorrhoeae MS11

95.082

79.221

0.753
  comE Neisseria gonorrhoeae MS11

95.082

79.221

0.753
  comE Neisseria gonorrhoeae MS11

95.082

79.221

0.753
  comE Neisseria gonorrhoeae MS11

95.082

79.221

0.753

Multiple sequence alignment