Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   EQH32_RS07540 Genome accession   NZ_CP035248
Coordinates   1476509..1477186 (-) Length   225 a.a.
NCBI ID   WP_000548959.1    Uniprot ID   Q9S1K2
Organism   Streptococcus pneumoniae strain TVO_1901939     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1471509..1482186
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH32_RS07510 (EQH32_07870) - 1471670..1472299 (-) 630 WP_000762087.1 NAD(P)-dependent oxidoreductase -
  EQH32_RS07515 (EQH32_07875) - 1472538..1472738 (+) 201 WP_001826938.1 hypothetical protein -
  EQH32_RS07520 (EQH32_07890) - 1473169..1473309 (+) 141 WP_000422775.1 MazG-like protein -
  EQH32_RS07525 (EQH32_07895) - 1473316..1473492 (+) 177 WP_000166031.1 MazG-like protein -
  EQH32_RS07530 (EQH32_07900) thrS 1473550..1475493 (+) 1944 WP_000608349.1 threonine--tRNA ligase -
  EQH32_RS07535 (EQH32_07905) - 1475542..1476516 (-) 975 WP_000887945.1 HAMP domain-containing histidine kinase -
  EQH32_RS07540 (EQH32_07910) braR 1476509..1477186 (-) 678 WP_000548959.1 response regulator transcription factor Regulator
  EQH32_RS07545 (EQH32_07915) - 1477342..1478415 (+) 1074 WP_001273823.1 DUF2974 domain-containing protein -
  EQH32_RS07550 (EQH32_07920) - 1478506..1478808 (-) 303 WP_000281608.1 hypothetical protein -
  EQH32_RS07555 (EQH32_07925) - 1478876..1479313 (-) 438 WP_001166786.1 Rrf2 family transcriptional regulator -
  EQH32_RS07560 (EQH32_07930) - 1479389..1480231 (-) 843 WP_000160943.1 metallophosphoesterase -
  EQH32_RS07565 (EQH32_07935) - 1480343..1480993 (+) 651 WP_000188505.1 metal-dependent transcriptional regulator -
  EQH32_RS07570 (EQH32_07945) - 1481113..1481850 (+) 738 WP_000749124.1 nicotinamide mononucleotide transporter -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25964.16 Da        Isoelectric Point: 5.1362

>NTDB_id=296364 EQH32_RS07540 WP_000548959.1 1476509..1477186(-) (braR) [Streptococcus pneumoniae strain TVO_1901939]
MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=296364 EQH32_RS07540 WP_000548959.1 1476509..1477186(-) (braR) [Streptococcus pneumoniae strain TVO_1901939]
ATGCACAAGATTTTATTAATAGAAGATGATCAGGTCATTCGTCAACAGATTGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTTGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCGGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCTAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAATGAATTCCAGATTTTA
CGCGTGTTATTTGAGCATGCAGGCAACATCGTAGCACGTGACGACCTGATGCGGGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9S1K2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

48.624

96.889

0.471
  vicR Streptococcus mutans UA159

35.319

100

0.369

Multiple sequence alignment