Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   EQH32_RS02965 Genome accession   NZ_CP035248
Coordinates   580538..582385 (+) Length   615 a.a.
NCBI ID   WP_001061113.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901939     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 575538..587385
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH32_RS02945 (EQH32_03105) - 576370..577149 (+) 780 WP_000290023.1 alpha/beta hydrolase family protein -
  EQH32_RS02950 (EQH32_03110) murM 577261..578481 (+) 1221 WP_000286563.1 peptidoglycan bridge formation alanyltransferase MurM -
  EQH32_RS02955 (EQH32_03115) murN 578486..579718 (+) 1233 WP_001229512.1 peptidoglycan bridge formation alanyltransferase MurN -
  EQH32_RS02960 (EQH32_03120) - 579797..580498 (+) 702 WP_001267416.1 M57 family metalloprotease -
  EQH32_RS02965 (EQH32_03125) uvrC 580538..582385 (+) 1848 WP_001061113.1 excinuclease ABC subunit UvrC Machinery gene
  EQH32_RS02970 (EQH32_03130) - 582375..583208 (+) 834 WP_025169225.1 metallophosphoesterase -
  EQH32_RS02975 (EQH32_03135) - 583390..584190 (-) 801 WP_000714633.1 amino acid ABC transporter substrate-binding protein -
  EQH32_RS02980 (EQH32_03140) - 584361..584966 (+) 606 WP_000670147.1 nitroreductase family protein -
  EQH32_RS02985 (EQH32_03145) pepV 584979..586379 (+) 1401 WP_000560282.1 dipeptidase PepV -
  EQH32_RS02990 (EQH32_03150) - 586433..587011 (+) 579 WP_000078142.1 uracil-DNA glycosylase family protein -

Sequence

Protein


Download         Length: 615 a.a.        Molecular weight: 70707.38 Da        Isoelectric Point: 9.2207

>NTDB_id=296326 EQH32_RS02965 WP_001061113.1 580538..582385(+) (uvrC) [Streptococcus pneumoniae strain TVO_1901939]
MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSYFRGIHDTKTEALVSEIVDFEFIVTESNIEALLLEIN
LIKENKPKYNIMLKDDKSYPFIKITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDDKIIDDLKSKMAVAAQSMEFERAAEYRDLIQAIGTLRTKQRVMAK
DLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNLFPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKAL
VDTKILKPQRGEKKQLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGTSPVSAMVV
FVNGRPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLIVIDGGQGQVNIAKQVIQEELGLDIPIAGLQ
KNDKHQTHELLFGDPLEVVDLSRNSQEFFLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSL
TKIKEASVDEIVEVGVPRAVAEAVQRKLNPQETEILLQVAEERVDYQTEGNHNKP

Nucleotide


Download         Length: 1848 bp        

>NTDB_id=296326 EQH32_RS02965 WP_001061113.1 580538..582385(+) (uvrC) [Streptococcus pneumoniae strain TVO_1901939]
ATGAACAACTTGATTAAATCAAAACTAGAGCTCTTGCCGACCAGCCCTGGTTGCTACATTCATAAGGATAAAAATGGCAC
CATTATCTATGTAGGAAAGGCTAAAAATCTGCGTAATCGAGTACGGTCCTATTTTCGTGGAATTCATGATACCAAGACAG
AGGCTCTGGTGTCTGAAATTGTGGATTTTGAATTTATCGTCACTGAGTCCAATATTGAGGCGCTTCTGCTGGAAATCAAC
TTGATCAAGGAAAATAAGCCCAAGTACAATATCATGCTCAAGGATGACAAGTCCTATCCTTTCATCAAAATCACCAATGA
GCGCTATCCACGGCTTATCATTACTCGTCAGGTCAAAAAGGACGGTGGTCTTTATTTTGGCCCTTATCCAGATGTGGGGG
CAGCCAATGAAATCAAGCGACTTCTAGATAGGATTTTCCCTTTTCGAAAATGTACCAACCCGCCCTCTAAGGTCTGTTTT
TATTACCATATCGGCCAGTGTATGGCCCACACCATCTGTAAGAAGGATGAGGCTTATTTCAAGTCTATGGCTCAGGAGGT
GTCTGATTTTCTGAAAGGTCAGGATGACAAAATCATCGATGATCTCAAGAGTAAAATGGCAGTAGCAGCACAAAGTATGG
AGTTTGAACGTGCGGCGGAATACCGTGACCTGATTCAGGCTATTGGAACGCTTCGAACCAAGCAACGGGTCATGGCTAAG
GATCTCCAAAATCGCGATGTCTTTGGCTACTATGTGGATAAGGGCTGGATGTGTGTGCAGGTTTTCTTTGTTCGTCAGGG
CAAGCTCATCGAGCGCGATGTCAATCTCTTCCCCTACTTCAATGATCCAGATGAGGATTTCTTGACCTATGTGGGACAAT
TCTATCAAGAAAAATCTCACCTAGTTCCCAATGAGGTACTGATTCCGCAGGATATTGACGAAGAAGCTGTCAAGGCTTTG
GTGGATACCAAGATTCTCAAACCCCAACGTGGAGAGAAAAAACAGCTGGTCAATCTAGCCATAAAAAATGCACGTGTTAG
TCTGGAGCAGAAATTTAACCTGCTAGAAAAATCAGTCGAAAAGACCCAAGGAGCTATTGAAAATCTAGGACGTTTGCTCC
AAATTCCGACTCCAGTTCGCATCGAGTCCTTCGATAACTCCAACATCATGGGGACCAGTCCTGTTTCAGCCATGGTGGTC
TTTGTTAACGGCAGGCCAAGTAAAAAAGATTACCGTAAGTACAAGATAAAAACCGTTGTTGGGCCGGACGACTATGCTAG
TATGAGAGAAGTCATTCGAAGACGCTATGGTCGAGTACAGCGTGAGGCTTTGACTCCTCCAGATTTGATTGTGATTGATG
GGGGGCAAGGTCAAGTCAATATTGCTAAGCAAGTCATCCAAGAAGAACTGGGCTTGGATATTCCAATTGCAGGTCTGCAA
AAGAATGATAAGCACCAAACCCATGAATTGCTCTTTGGAGATCCGCTGGAAGTGGTGGACTTGTCTCGCAATTCTCAGGA
ATTTTTCCTCCTCCAACGCATTCAAGATGAGGTCCACCGCTTTGCCATTACCTTCCACCGCCAACTGCGCTCCAAAAATT
CTTTCTCATCTCAATTGGATGGGATTGATGGTCTGGGACCTAAACGCAAGCAAAATCTCATGAGGCACTTCAAGTCTCTG
ACCAAAATCAAGGAAGCCAGTGTGGATGAGATTGTCGAAGTTGGAGTACCAAGAGCAGTAGCAGAGGCTGTGCAAAGAAA
GTTGAACCCGCAGGAAACAGAAATCTTGCTTCAAGTGGCGGAAGAAAGAGTAGATTACCAAACGGAAGGAAACCACAATA
AACCATAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(196-228)

GIY-YIG catalytic domain (GIY-YIG)

(17-90)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae R6

98.374

100

0.984
  uvrC Streptococcus pneumoniae TIGR4

98.374

100

0.984
  uvrC Streptococcus pneumoniae D39

98.374

100

0.984

Multiple sequence alignment