Detailed information NTG0029630

Bioinformatically predicted

Overview

• Name: ruvB
• Type: Machinery gene
• Locus tag: SUB_RS00370
• Genome accession: NC_012004
• Coordinates: 63179..64183 (+)
• Length: 334 a.a.
• NCBI ID: WP_012657625.1
• Uniprot ID: B9DSU1
• Organism: Streptococcus uberis 0140J
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 58179..69183

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SUB_RS00350 (SUB0054)	purE	58762..59250 (+)	489	WP_012657620.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
SUB_RS00355 (SUB0055)	purK	59237..60310 (+)	1074	WP_012657621.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
SUB_RS00360 (SUB0056)	purB	60624..61916 (+)	1293	WP_012657622.1	adenylosuccinate lyase	-
SUB_RS00365 (SUB0057)	comR	62035..62949 (+)	915	WP_269441089.1	helix-turn-helix domain-containing protein	Regulator
SUB_RS09690	-	63049..63147 (+)	99	WP_198433762.1	quorum-sensing system DWW-type pheromone	-
SUB_RS00370 (SUB0059)	ruvB	63179..64183 (+)	1005	WP_012657625.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
SUB_RS00375 (SUB0060)	-	64434..64862 (+)	429	WP_012657626.1	low molecular weight protein-tyrosine-phosphatase	-
SUB_RS00380 (SUB0061)	-	64867..65280 (+)	414	WP_012657627.1	membrane protein	-
SUB_RS00385 (SUB0062)	-	65277..67055 (+)	1779	WP_012657628.1	acyltransferase family protein	-

Sequence

Protein

• Length: 334 a.a.
• Molecular weight: 37690.33 Da
• Isoelectric Point: 4.6255

>NTDB_id=29630 SUB_RS00370 WP_012657625.1 63179..64183(+) (ruvB) [Streptococcus uberis 0140J]
MTRILDNDLMGDEELIERTLRPQYLKEYIGQDKVKNQLSIFIEAAKLRDESLDHVLLFGPPGLGKTTMAFVIANELGVNL
KQTSGPAIEKAGDLVAILNDLEPGDVLFIDEIHRMPMAVEEVLYSAMEDFYIDIMIGAGDTSRSVHLELPPFTLIGATTR
AGMLSNPLRARFGITGHMEYYQVDDLTEIVERTSDIFEMAIVHEAALELAKRSRGTPRIANRLLKRVRDYAQIMGDGVIT
KEMTDKALEMLDVDHEGLDYVDQKILRTMIEMYNGGPVGLGTLSVNIAEERDTVEDMYEPYLIQKGFIMRTRTGRVATEK
AYRHLKYPLDTKTE

Nucleotide

• Length: 1005 bp

>NTDB_id=29630 SUB_RS00370 WP_012657625.1 63179..64183(+) (ruvB) [Streptococcus uberis 0140J]
ATGACTAGAATATTAGATAACGATTTAATGGGTGATGAAGAGTTAATTGAACGGACGCTTCGCCCTCAATACCTGAAAGA
ATACATTGGACAAGATAAAGTTAAAAATCAACTGTCTATCTTTATTGAAGCAGCGAAATTAAGAGATGAATCACTTGATC
ATGTCTTACTCTTTGGACCTCCGGGCCTAGGTAAGACAACCATGGCATTCGTTATTGCTAATGAGCTTGGTGTTAATTTA
AAACAAACTTCCGGTCCAGCTATTGAAAAGGCAGGAGACCTTGTTGCTATTTTAAATGATTTAGAACCCGGAGATGTTTT
ATTTATTGATGAGATTCATCGTATGCCAATGGCTGTTGAAGAAGTTCTATATAGCGCCATGGAAGATTTTTACATTGATA
TTATGATTGGAGCAGGAGACACAAGTAGGAGTGTTCATCTAGAACTTCCTCCTTTTACATTAATTGGAGCAACGACTCGT
GCGGGGATGTTATCAAATCCTCTAAGAGCTCGCTTTGGAATCACTGGGCATATGGAATATTATCAGGTTGATGATCTGAC
GGAAATTGTGGAACGTACCTCTGATATCTTCGAAATGGCTATTGTCCATGAAGCTGCTTTGGAATTAGCAAAACGTAGTC
GAGGAACCCCCCGAATTGCTAACCGCTTATTAAAAAGGGTTCGAGATTATGCTCAGATTATGGGTGATGGGGTAATCACG
AAAGAAATGACCGACAAGGCTTTAGAAATGCTTGATGTTGATCATGAAGGTTTAGATTATGTCGATCAGAAAATTCTCAG
AACCATGATTGAAATGTATAACGGTGGTCCAGTGGGATTAGGAACCTTATCTGTCAATATTGCTGAAGAAAGAGATACTG
TTGAAGATATGTATGAGCCTTATCTTATTCAGAAAGGGTTTATTATGAGAACCAGAACGGGCCGAGTAGCAACAGAAAAA
GCCTACCGTCACCTGAAGTACCCATTAGATACAAAAACGGAATAG

Domains

Predicted by InterProScan.

• RuvB C-terminal winged helix domain (WHD_RuvB) (256-326)

• RuvB AAA lid domain (AAA_lid_4) (181-254)

• Holliday junction DNA helicase RuvB P-loop domain (RuvB_N) (20-178)

3D structure

• AlphaFold DB: B9DSU1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ruvB	Streptococcus pneumoniae TIGR4	88.253	99.401	0.877
ruvB	Streptococcus pneumoniae R6	87.952	99.401	0.874
ruvB	Streptococcus pneumoniae D39	87.952	99.401	0.874
ruvB	Bacillus subtilis subsp. subtilis str. 168	60.185	97.006	0.584
ruvB	Helicobacter pylori 26695	49.387	97.605	0.482
ruvB	Synechocystis sp. PCC 6803	49.515	92.515	0.458