Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   EQH33_RS02775 Genome accession   NZ_CP035247
Coordinates   559896..561740 (+) Length   614 a.a.
NCBI ID   WP_001061132.1    Uniprot ID   C1CJ89
Organism   Streptococcus pneumoniae strain TVO_1901940     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 554896..566740
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH33_RS02755 (EQH33_02955) - 555728..556507 (+) 780 WP_000290024.1 alpha/beta hydrolase family protein -
  EQH33_RS02760 (EQH33_02960) murM 556619..557839 (+) 1221 WP_001812743.1 peptidoglycan bridge formation alanyltransferase MurM -
  EQH33_RS02765 (EQH33_02965) murN 557844..559076 (+) 1233 WP_001229518.1 peptidoglycan bridge formation alanyltransferase MurN -
  EQH33_RS02770 (EQH33_02970) - 559155..559856 (+) 702 WP_001267410.1 M57 family metalloprotease -
  EQH33_RS02775 (EQH33_02975) uvrC 559896..561740 (+) 1845 WP_001061132.1 excinuclease ABC subunit UvrC Machinery gene
  EQH33_RS02780 (EQH33_02980) - 561730..562563 (+) 834 WP_001015782.1 metallophosphoesterase -
  EQH33_RS02785 (EQH33_02985) - 562745..563545 (-) 801 WP_000714613.1 amino acid ABC transporter substrate-binding protein -
  EQH33_RS02790 (EQH33_02990) - 563716..564321 (+) 606 WP_000670172.1 nitroreductase family protein -
  EQH33_RS02795 (EQH33_02995) pepV 564334..565734 (+) 1401 WP_000560280.1 dipeptidase PepV -
  EQH33_RS02800 (EQH33_03000) - 565788..566366 (+) 579 WP_000078151.1 uracil-DNA glycosylase family protein -

Sequence

Protein


Download         Length: 614 a.a.        Molecular weight: 70436.96 Da        Isoelectric Point: 9.1183

>NTDB_id=296206 EQH33_RS02775 WP_001061132.1 559896..561740(+) (uvrC) [Streptococcus pneumoniae strain TVO_1901940]
MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSYFRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEIN
LIKENKPKYNIMLKDDKSYPFIKITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDDKIIDDLKSKMAVAAQSMEFERAAEYRDLIQAIGTLRTKQRVMAK
DLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNLFPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKAL
VDSKILKPQRGEKKQLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGTSPVSAMVV
FVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLIVIDGGQGQVNIAKQVIQEELGLDIPIAGLQ
KNDKHQTHELLFGDPLEVVDLSRNSQEFFLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSL
TKIKEASVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP

Nucleotide


Download         Length: 1845 bp        

>NTDB_id=296206 EQH33_RS02775 WP_001061132.1 559896..561740(+) (uvrC) [Streptococcus pneumoniae strain TVO_1901940]
ATGAACAACTTGATTAAATCAAAACTAGAGCTCTTGCCGACCAGCCCTGGTTGCTACATTCATAAGGATAAAAATGGCAC
CATTATCTATGTAGGAAAGGCTAAAAATCTGCGTAATCGAGTACGGTCCTATTTTCGTGGAAGTCATGATACCAAGACAG
AGGCTCTGGTGTCTGAAATTGTGGATTTTGAATTTATTGTTACGGAGTCTAATATTGAGGCACTTCTCCTAGAAATCAAC
CTGATCAAGGAAAACAAGCCCAAGTACAATATCATGCTCAAGGATGACAAGTCCTATCCTTTCATCAAAATCACCAATGA
GCGCTATCCACGGCTTATCATTACTCGTCAGGTCAAAAAGGACGGTGGTCTTTATTTTGGCCCTTATCCAGATGTGGGGG
CAGCCAATGAAATCAAGCGACTTCTAGATAGGATTTTCCCTTTTCGAAAATGTACCAACCCGCCCTCTAAGGTCTGTTTT
TATTACCATATCGGCCAGTGTATGGCCCACACCATCTGTAAGAAGGATGAGGCTTATTTCAAGTCTATGGCTCAGGAGGT
GTCTGATTTTCTGAAAGGTCAGGATGACAAAATCATCGATGATCTCAAGAGTAAAATGGCAGTAGCAGCACAAAGTATGG
AGTTTGAACGTGCGGCGGAATACCGTGACCTGATTCAGGCTATTGGAACGCTTCGAACCAAGCAACGGGTCATGGCGAAA
GATTTGCAAAATCGCGATGTCTTTGGCTACTATGTGGATAAGGGCTGGATGTGTGTGCAGGTTTTCTTTGTCCGTCAGGG
TAAGCTTATCGAGCGCGATGTCAATCTCTTCCCCTACTTCAATGATCCAGATGAGGATTTTTTGACCTATGTAGGACAAT
TCTATCAAGAAAAATCTCATCTAGTTCCCAATGAGGTACTGATTCCGCAGGATATTGACGAAGAGGCTGTCAAGGCCTTG
GTGGATTCCAAGATTCTTAAGCCTCAACGTGGAGAGAAAAAACAACTGGTCAATCTAGCCATAAAAAATGCTCGTGTTAG
TCTAGAGCAGAAGTTCAATCTGCTAGAAAAATCTGTCGAAAAGACTCAAGGAGCTATTGAAAATCTAGGGCGTTTGCTCC
AAATCCCGACCCCAGTACGTATCGAGTCCTTCGATAACTCTAATATCATGGGAACTAGCCCTGTTTCGGCTATGGTGGTC
TTTGTCAACGGTAAACCGAGTAAGAAGGATTACCGTAAGTACAAGATAAAAACGGTTGTTGGACCAGACGACTATGCCAG
CATGAGAGAGGTCATTCGCAGACGCTATGGTCGAGTACAGCGTGAGGCTTTGACTCCTCCAGATTTGATTGTGATTGATG
GGGGGCAAGGTCAAGTCAATATCGCTAAGCAGGTTATCCAAGAGGAACTGGGCTTGGATATTCCAATTGCTGGGCTGCAA
AAGAATGATAAGCACCAAACCCATGAATTGCTCTTTGGAGATCCGCTTGAGGTGGTGGACTTGTCTCGCAATTCTCAGGA
ATTTTTCCTCCTCCAACGCATCCAAGATGAGGTGCACCGCTTTGCTATCACTTTCCACCGCCAACTGCGCTCCAAAAATT
CTTTCTCATCTCAATTGGATGGGATTGATGGTCTGGGACCTAAACGCAAGCAAAATCTCATGAGGCATTTCAAGTCTTTG
ACCAAAATCAAGGAAGCCAGTGTGGATGAGATTGTCGAAGTTGGGGTACCTAGAGTCGTTGCAGAGGCTGTGCAAAGAAA
GTTGAACCCGCAGGGAGAAGCCTTGCCTCAAGTAGCAGAAGAAAGAGTAGATTACCAAACGGAAGGAAACCACAATGAAC
CATAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(196-228)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)

GIY-YIG catalytic domain (GIY-YIG)

(17-90)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C1CJ89

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

99.837

100

0.998
  uvrC Streptococcus pneumoniae R6

99.674

100

0.997
  uvrC Streptococcus pneumoniae D39

99.674

100

0.997

Multiple sequence alignment