Detailed information NTG0296029

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: EQH35_RS09205
• Genome accession: NZ_CP035245
• Coordinates: 1775208..1776107 (-)
• Length: 299 a.a.
• NCBI ID: WP_000904867.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901943
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1770208..1781107

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH35_RS09180 (EQH35_09700)	rsmA	1770538..1771410 (-)	873	WP_001216830.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
EQH35_RS09185 (EQH35_09705)	-	1771541..1771849 (-)	309	WP_000333257.1	hypothetical protein	-
EQH35_RS09190 (EQH35_09710)	-	1771842..1772483 (-)	642	WP_000565531.1	ABC transporter ATP-binding protein	-
EQH35_RS09195 (EQH35_09715)	-	1772485..1774515 (-)	2031	WP_000825263.1	bacteriocin-associated integral membrane family protein	-
EQH35_RS09200 (EQH35_09720)	-	1774592..1774888 (-)	297	WP_000815394.1	lactococcin 972 family bacteriocin	-
EQH35_RS09205 (EQH35_09725)	comR	1775208..1776107 (-)	900	WP_000904867.1	helix-turn-helix domain-containing protein	Regulator
EQH35_RS09210 (EQH35_09730)	rnmV	1776179..1776739 (-)	561	WP_000664448.1	ribonuclease M5	-
EQH35_RS09215 (EQH35_09735)	-	1776739..1777512 (-)	774	WP_000575607.1	TatD family hydrolase	-
EQH35_RS09220 (EQH35_09745)	-	1777818..1778525 (-)	708	Protein_1828	DUF1542 domain-containing protein	-
EQH35_RS09225 (EQH35_09750)	rpmH	1778734..1778868 (-)	135	WP_000831906.1	50S ribosomal protein L34	-
EQH35_RS09230 (EQH35_09755)	-	1779013..1780227 (-)	1215	WP_000666469.1	pyridoxal phosphate-dependent aminotransferase	-
EQH35_RS09235 (EQH35_09760)	-	1780383..1780676 (-)	294	WP_000977365.1	hypothetical protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35191.04 Da
• Isoelectric Point: 5.0703

>NTDB_id=296029 EQH35_RS09205 WP_000904867.1 1775208..1776107(-) (comR) [Streptococcus pneumoniae strain TVO_1901943]
MLIGQKIKEIRIEKGISRPDFCGDEQGLTVRQLSRIESGASQPSLPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAKLIGDGFLVKKLTEEWQEDVKKYL

Nucleotide

• Length: 900 bp

>NTDB_id=296029 EQH35_RS09205 WP_000904867.1 1775208..1776107(-) (comR) [Streptococcus pneumoniae strain TVO_1901943]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGG
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGCCTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTTCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGCCTCAGATTATAGAAAAAGAAGCTTATTCAATAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTCTT
TCTTTTGGAACAGAAGAAGGTAACTCAAATAGAGAATTACTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCTTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGTAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGAAGCTAATTGGAGATGGATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (7-59)

• ComR tetratricopeptide (ComR_TPR) (70-291)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	37.755	98.328	0.371
comR	Streptococcus suis P1/7	37.801	97.324	0.368
comR	Streptococcus suis 05ZYH33	37.801	97.324	0.368