Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Regulator
Locus tag   EQH36_RS09090 Genome accession   NZ_CP035244
Coordinates   1778618..1779238 (-) Length   206 a.a.
NCBI ID   WP_000839908.1    Uniprot ID   A0A0H2URP6
Organism   Streptococcus pneumoniae strain TVO_1901945     
Function   fratricide immunity (predicted from homology)   
Competence regulation

Genomic Context

Location: 1773618..1784238
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH36_RS09065 (EQH36_09550) recA 1773995..1775161 (-) 1167 WP_001085462.1 recombinase RecA -
  EQH36_RS09070 (EQH36_09555) cinA 1775216..1776472 (-) 1257 WP_000642709.1 competence/damage-inducible protein A Machinery gene
  EQH36_RS09075 (EQH36_09560) brpA 1776557..1777573 (-) 1017 WP_000239278.1 biofilm formation/cell division transcriptional regulator BrpA -
  EQH36_RS09080 (EQH36_09565) - 1777581..1778099 (-) 519 WP_061758489.1 GNAT family N-acetyltransferase -
  EQH36_RS09085 (EQH36_09570) tsaE 1778089..1778532 (-) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  EQH36_RS09090 (EQH36_09575) comM 1778618..1779238 (-) 621 WP_000839908.1 hypothetical protein Regulator
  EQH36_RS09095 (EQH36_09585) - 1779621..1780484 (-) 864 WP_001093618.1 helix-turn-helix domain-containing protein -
  EQH36_RS10870 (EQH36_09590) - 1780676..1780846 (+) 171 WP_001227862.1 PhrA family quorum-sensing system peptide -
  EQH36_RS09100 (EQH36_09595) pneA1 1780949..1781173 (+) 225 WP_000181086.1 two-peptide bacteriocin subunit PneA1 -
  EQH36_RS09105 (EQH36_09600) pneA2 1781180..1781368 (+) 189 WP_000786759.1 two-peptide bacteriocin subunit PneA2 -

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 23552.72 Da        Isoelectric Point: 10.1254

>NTDB_id=295908 EQH36_RS09090 WP_000839908.1 1778618..1779238(-) (comM) [Streptococcus pneumoniae strain TVO_1901945]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF

Nucleotide


Download         Length: 621 bp        

>NTDB_id=295908 EQH36_RS09090 WP_000839908.1 1778618..1779238(-) (comM) [Streptococcus pneumoniae strain TVO_1901945]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTAGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATATTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2URP6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Streptococcus pneumoniae D39

100

100

1
  comM Streptococcus pneumoniae R6

100

100

1
  comM Streptococcus pneumoniae TIGR4

100

100

1
  comM Streptococcus mitis NCTC 12261

38.974

94.66

0.369
  comM Streptococcus mitis SK321

38.974

94.66

0.369