Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   CFC57_RS07955 Genome accession   NZ_CP029751
Coordinates   1603302..1604276 (-) Length   324 a.a.
NCBI ID   WP_000697220.1    Uniprot ID   W8U5L8
Organism   Staphylococcus aureus strain Smith     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1598302..1609276
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CFC57_RS07915 (CFC57_08270) gcvT 1598801..1599892 (-) 1092 WP_000093356.1 glycine cleavage system aminomethyltransferase GcvT -
  CFC57_RS07920 (CFC57_08275) - 1600051..1600575 (-) 525 WP_001015120.1 shikimate kinase -
  CFC57_RS07925 (CFC57_08280) - 1600565..1600711 (-) 147 WP_001789879.1 hypothetical protein -
  CFC57_RS07930 (CFC57_08285) comGF 1600808..1601305 (-) 498 WP_029656266.1 competence type IV pilus minor pilin ComGF Machinery gene
  CFC57_RS07935 (CFC57_08290) comGE 1601223..1601522 (-) 300 WP_000844413.1 hypothetical protein Machinery gene
  CFC57_RS07940 (CFC57_08295) comGD 1601509..1601955 (-) 447 WP_001796473.1 competence type IV pilus minor pilin ComGD Machinery gene
  CFC57_RS07945 (CFC57_08300) comGC 1601933..1602244 (-) 312 WP_000472256.1 competence type IV pilus major pilin ComGC Machinery gene
  CFC57_RS07950 (CFC57_08305) comGB 1602258..1603330 (-) 1073 Protein_1529 competence type IV pilus assembly protein ComGB -
  CFC57_RS07955 (CFC57_08310) comGA 1603302..1604276 (-) 975 WP_000697220.1 competence type IV pilus ATPase ComGA Machinery gene
  CFC57_RS07960 (CFC57_08315) - 1604328..1604951 (-) 624 WP_001223011.1 MBL fold metallo-hydrolase -
  CFC57_RS07965 (CFC57_08320) - 1604948..1605277 (-) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  CFC57_RS07970 (CFC57_08325) - 1605277..1606263 (-) 987 WP_000161315.1 ROK family glucokinase -
  CFC57_RS07975 (CFC57_08330) - 1606260..1606463 (-) 204 WP_000087561.1 YqgQ family protein -
  CFC57_RS07980 (CFC57_08335) - 1606444..1607907 (-) 1464 WP_111131284.1 rhomboid family intramembrane serine protease -
  CFC57_RS07985 (CFC57_08340) - 1607919..1608458 (-) 540 WP_000164543.1 5-formyltetrahydrofolate cyclo-ligase -
  CFC57_RS07990 (CFC57_08345) rpmG 1608667..1608816 (-) 150 WP_001265709.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 324 a.a.        Molecular weight: 36897.96 Da        Isoelectric Point: 8.8516

>NTDB_id=295887 CFC57_RS07955 WP_000697220.1 1603302..1604276(-) (comGA) [Staphylococcus aureus strain Smith]
MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNSIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYHF
NKIYFLRISTLPLSLGQESCVIRIVPQFFQQQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGISVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSHNHSLPSSFKNLEDKLDDMTKAGVICETTM
DKYI

Nucleotide


Download         Length: 975 bp        

>NTDB_id=295887 CFC57_RS07955 WP_000697220.1 1603302..1604276(-) (comGA) [Staphylococcus aureus strain Smith]
TTGAAGATTCTATTTCAAGAAATAATTAATAAAGCGATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA
TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTATGAACAAATTGGGAATAGCATTTATCAAAAGTTAT
TAGTTTATATGAAGTTTCAAGCTGGGCTTGATGTTTCTACACAGCAAGTCGCACAGAGCGGTCGATATAGTTACCATTTC
AATAAAATATATTTTTTGAGAATATCAACTTTACCATTGTCACTTGGCCAAGAAAGTTGTGTAATCAGAATTGTACCTCA
ATTTTTTCAACAACAGAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAATAAGAAACAAGGATTACTATTGT
TTAGTGGACCTACTGGTTCAGGAAAGAGTACATTAATGTATCAAATGGTCTCATACGCGAATAAAGCCTTGAATTTAAAT
GTAATTTCTATAGAAGATCCTGTAGAGATGCAAATTCCTGGTATTGTCCAAATTAATGTGAATGATAAAGCTGGCATTAA
CTATGTAAATTCGTTTAAAGCTATTTTAAGATGTGATCCTGATGTTATTTTAATAGGTGAAATCAGAGATAAAGATGTTG
CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTTGTTCTGACTACATTGCATGCAACTGATTGTAAAGGTGCTATT
TTAAGGCTATTAGAAATGGGCATTTCTGTACAAGAATTGATACAGGCAACTAACTTAATTATAAACCAACGACTTGTAAC
TACTATTAAGCAACAGCGACAATTAGTATGTGAAATTCTATCTCAGCAACAACTCCGATATTTCTTTTCCCATAATCATT
CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAACTACAATG
GATAAATACATTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(7-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB W8U5L8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Staphylococcus aureus MW2

100

100

1
  comGA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment