Detailed information NTG0295869

Bioinformatically predicted

Overview

• Name: ccrA
• Type: Machinery gene
• Locus tag: CFC57_RS00490
• Genome accession: NZ_CP029751
• Coordinates: 59131..60480 (-)
• Length: 449 a.a.
• NCBI ID: WP_000815653.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain Smith
• Function: promote SCCmec transfer (predicted from homology) Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
SCCmec	57478..65757	59131..60480	within	0

Gene organization within MGE regions

Location: 57478..65757

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CFC57_RS00485 (CFC57_00500)	ccrB	57478..59109 (-)	1632	WP_001186606.1	recombinase family protein	Machinery gene
CFC57_RS00490 (CFC57_00505)	ccrA	59131..60480 (-)	1350	WP_000815653.1	recombinase family protein	Machinery gene
CFC57_RS00495 (CFC57_00510)	-	60714..62507 (-)	1794	WP_001077071.1	DUF927 domain-containing protein	-
CFC57_RS00500 (CFC57_00515)	-	62507..62800 (-)	294	WP_001036501.1	single-stranded DNA-binding protein	-
CFC57_RS00505 (CFC57_00520)	-	63031..64172 (+)	1142	WP_100199980.1	IS3 family transposase	-
CFC57_RS00510 (CFC57_00525)	-	64243..65757 (-)	1515	WP_000594570.1	hypothetical protein	-

Sequence

Protein

• Length: 449 a.a.
• Molecular weight: 52642.21 Da
• Isoelectric Point: 10.0062

>NTDB_id=295869 CFC57_RS00490 WP_000815653.1 59131..60480(-) (ccrA) [Staphylococcus aureus strain Smith]
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINYYSDKQSGRKDNRSGYRQMTQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYRVHILSVHDGYFDMDQAFDRFKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYEYH
NGTFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRSQKQTKQTPSDNQLKQKIKCPCCNATLTNMTVRKKNHTLRYYVCPKNMNASRFVCDFKGINAQTLEDKVLEV
CRDFYQNQRIYTKIKSAIDKRIKRQRNIEKHHTLTQEQLIEKLAQGIIDAETFREQTQSLRQQPQRTTSINGHQIQHTIQ
NIIQKRFTLNILHPYIETIHITKDKNLIGIYFKNEPLNIVNQAMQSSIA

Nucleotide

• Length: 1350 bp

>NTDB_id=295869 CFC57_RS00490 WP_000815653.1 59131..60480(-) (ccrA) [Staphylococcus aureus strain Smith]
ATGAAACAAGTCATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAAGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTATTATAGCGACAAACAATCAGGACGCAAAGATAATCGTAGTGGGT
ATCGACAAATGACACAATTAATTCAACAAGGACAATGTGACATATTATGCTGTTATCGTCTTAATAGGTTGCATCGTAAT
TTGAAAAATGCATTAAAACTCATAAAATTATGTCAAACATATCGCGTTCATATCTTAAGTGTGCATGATGGTTATTTTGA
TATGGATCAAGCTTTCGACCGATTCAAGCTTAATATTTTTATCAGCTTGGCCGAACTTGAATCAGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACCCATGCGCCCTTTGGTTACGAATATCAC
AACGGAACATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGTCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATCATCA
ATCCTAATTATTGTGGTCGTGTCAACAATCAATATGGCCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATCGCAAAAACAAACCAAACAGACACCTTCGGATAACCAACTAAAACAAAAAATCAA
ATGCCCATGTTGTAATGCAACACTTACGAATATGACCGTTAGAAAAAAGAATCATACATTACGTTACTACGTCTGTCCTA
AAAACATGAATGCTTCACGCTTTGTCTGTGATTTTAAAGGCATCAATGCACAAACACTTGAAGATAAAGTATTAGAAGTG
TGCCGAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAAGTGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAACATCACACATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATTGATGCAGAAACGTTCA
GAGAACAAACGCAATCATTACGTCAACAACCGCAACGCACTACATCTATAAATGGGCATCAAATACAACACACCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGCACCCCTACATTGAAACCATTCACATTACGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAGCCACTCAATATCGTCAATCAAGCCATGCAATCATCGATTGCATAA

Domains

Predicted by InterproScan.

• Recombinase (Recombinase) (169-250)

• Recombinase zinc beta ribbon domain (Zn_ribbon_recom) (262-321)

• Resolvase, N terminal domain (Resolvase) (4-147)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccrA	Staphylococcus aureus N315	97.773	100	0.978
ccrA	Staphylococcus aureus COL	74.388	100	0.744