Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   EQH38_RS04275 Genome accession   NZ_CP035242
Coordinates   791085..791762 (+) Length   225 a.a.
NCBI ID   WP_000548959.1    Uniprot ID   Q9S1K2
Organism   Streptococcus pneumoniae strain TVO_1901947     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 786085..796762
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH38_RS04245 (EQH38_04495) - 786421..787098 (-) 678 WP_000260184.1 nicotinamide mononucleotide transporter family protein -
  EQH38_RS04250 (EQH38_04505) - 787277..787927 (-) 651 WP_000188505.1 metal-dependent transcriptional regulator -
  EQH38_RS04255 (EQH38_04510) - 788039..788881 (+) 843 WP_000160934.1 metallophosphoesterase -
  EQH38_RS04260 (EQH38_04515) - 788957..789394 (+) 438 WP_001166786.1 Rrf2 family transcriptional regulator -
  EQH38_RS04265 (EQH38_04520) - 789463..789765 (+) 303 WP_000281613.1 hypothetical protein -
  EQH38_RS04270 (EQH38_04525) - 789856..790929 (-) 1074 WP_001273826.1 DUF2974 domain-containing protein -
  EQH38_RS04275 (EQH38_04530) braR 791085..791762 (+) 678 WP_000548959.1 response regulator transcription factor Regulator
  EQH38_RS04280 (EQH38_04535) - 791755..792729 (+) 975 WP_000887953.1 HAMP domain-containing histidine kinase -
  EQH38_RS04285 (EQH38_04540) thrS 792778..794721 (-) 1944 WP_000608349.1 threonine--tRNA ligase -
  EQH38_RS04290 (EQH38_04545) - 794779..795102 (-) 324 WP_000422776.1 MazG-like protein -
  EQH38_RS04295 - 795359..795722 (-) 364 Protein_816 hypothetical protein -
  EQH38_RS04300 (EQH38_04565) - 795961..796576 (+) 616 Protein_817 NAD(P)-dependent oxidoreductase -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25964.16 Da        Isoelectric Point: 5.1362

>NTDB_id=295634 EQH38_RS04275 WP_000548959.1 791085..791762(+) (braR) [Streptococcus pneumoniae strain TVO_1901947]
MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=295634 EQH38_RS04275 WP_000548959.1 791085..791762(+) (braR) [Streptococcus pneumoniae strain TVO_1901947]
ATGCACAAGATTTTATTAATAGAAGATGATCAGGTCATTCGTCAACAGATTGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCGGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCTAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAATGAATTCCAGATTTTA
CGCGTGTTATTTGAGCATGCAGGCAACATCGTAGCACGTGACGACCTGATGCGGGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9S1K2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

48.624

96.889

0.471
  vicR Streptococcus mutans UA159

35.319

100

0.369