Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   EQH39_RS07065 Genome accession   NZ_CP035241
Coordinates   1412784..1413461 (-) Length   225 a.a.
NCBI ID   WP_000548959.1    Uniprot ID   Q9S1K2
Organism   Streptococcus pneumoniae strain TVO_1901948     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1407784..1418461
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH39_RS07040 (EQH39_07415) - 1407958..1408587 (-) 630 WP_000762082.1 NAD(P)-dependent oxidoreductase -
  EQH39_RS07045 - 1408824..1409187 (+) 364 Protein_1407 hypothetical protein -
  EQH39_RS10355 (EQH39_07435) - 1409444..1409767 (+) 324 Protein_1408 MazG-like protein -
  EQH39_RS07055 (EQH39_07440) thrS 1409825..1411768 (+) 1944 WP_000608349.1 threonine--tRNA ligase -
  EQH39_RS07060 (EQH39_07445) - 1411817..1412791 (-) 975 WP_000887954.1 HAMP domain-containing histidine kinase -
  EQH39_RS07065 (EQH39_07450) braR 1412784..1413461 (-) 678 WP_000548959.1 response regulator transcription factor Regulator
  EQH39_RS07070 (EQH39_07455) - 1413617..1414690 (+) 1074 WP_001273831.1 DUF2974 domain-containing protein -
  EQH39_RS07075 (EQH39_07460) - 1414781..1415083 (-) 303 WP_000281600.1 hypothetical protein -
  EQH39_RS07080 (EQH39_07465) - 1415152..1415589 (-) 438 WP_001166786.1 Rrf2 family transcriptional regulator -
  EQH39_RS07085 (EQH39_07470) - 1415665..1416507 (-) 843 WP_000160959.1 metallophosphoesterase -
  EQH39_RS07090 (EQH39_07475) - 1416619..1417269 (+) 651 WP_000188506.1 metal-dependent transcriptional regulator -
  EQH39_RS07095 (EQH39_07485) - 1417388..1418095 (+) 708 WP_000749107.1 nicotinamide mononucleotide transporter family protein -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25964.16 Da        Isoelectric Point: 5.1362

>NTDB_id=295532 EQH39_RS07065 WP_000548959.1 1412784..1413461(-) (braR) [Streptococcus pneumoniae strain TVO_1901948]
MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=295532 EQH39_RS07065 WP_000548959.1 1412784..1413461(-) (braR) [Streptococcus pneumoniae strain TVO_1901948]
ATGCACAAGATTTTATTAATAGAAGATGATCAGGTCATTCGTCAACAGATTGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCGGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCTAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAATGAATTCCAGATTTTA
CGCGTGTTATTTGAGCATGCAGGCAACATCGTAGCACGTGACGACCTGATGCGGGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTATGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9S1K2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

48.624

96.889

0.471
  vicR Streptococcus mutans UA159

35.319

100

0.369