Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   EQH39_RS02620 Genome accession   NZ_CP035241
Coordinates   526784..528631 (+) Length   615 a.a.
NCBI ID   WP_001061111.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901948     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 521784..533631
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH39_RS02600 (EQH39_02745) - 522617..523396 (+) 780 WP_000290001.1 alpha/beta hydrolase family protein -
  EQH39_RS02605 (EQH39_02750) murM 523508..524728 (+) 1221 WP_001810543.1 peptidoglycan bridge formation alanyltransferase MurM -
  EQH39_RS02610 (EQH39_02755) murN 524733..525965 (+) 1233 WP_001229500.1 peptidoglycan bridge formation alanyltransferase MurN -
  EQH39_RS02615 (EQH39_02760) - 526044..526745 (+) 702 WP_001267409.1 M57 family metalloprotease -
  EQH39_RS02620 (EQH39_02765) uvrC 526784..528631 (+) 1848 WP_001061111.1 excinuclease ABC subunit UvrC Machinery gene
  EQH39_RS02625 (EQH39_02770) - 528621..529418 (+) 798 WP_001015749.1 metallophosphoesterase -
  EQH39_RS02630 (EQH39_02775) - 529600..530400 (-) 801 WP_000714633.1 amino acid ABC transporter substrate-binding protein -
  EQH39_RS02635 (EQH39_02780) - 530571..531176 (+) 606 WP_000670161.1 nitroreductase family protein -
  EQH39_RS02640 (EQH39_02785) pepV 531189..532589 (+) 1401 WP_000560281.1 dipeptidase PepV -
  EQH39_RS02645 (EQH39_02790) - 532643..533221 (+) 579 WP_000078147.1 uracil-DNA glycosylase family protein -

Sequence

Protein


Download         Length: 615 a.a.        Molecular weight: 70685.20 Da        Isoelectric Point: 8.7224

>NTDB_id=295496 EQH39_RS02620 WP_001061111.1 526784..528631(+) (uvrC) [Streptococcus pneumoniae strain TVO_1901948]
MNNLIKPKLELLPTSPGCYIYKDKNGTIIYVGKAKNLRNRVRSYFRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEIN
LIKENKPKYNIMLKDDKSYPFIKITNEHYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
YYHIGQCMAHTICKNDEAYFKSMAQEVSDFLKGQDDKIIDDLKSKMAVTAQSMEFERAAEYRDLIQAIGTLRTKQRVMAK
DLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNLFPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKAL
VDTKILKPQRGEKKQLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGTSPVSAMVV
FVNGRPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLIVIDGGQGQVNIAKQVIQEELGLDIPIAGLQ
KNDKHQTHELLFGDPLEVVDLSRNSQEFFLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSL
TKIKEAGVDEIVEVGVPRAVAEAVQRKLNPQETEILLQVAEERVDYQTEGNHNEP

Nucleotide


Download         Length: 1848 bp        

>NTDB_id=295496 EQH39_RS02620 WP_001061111.1 526784..528631(+) (uvrC) [Streptococcus pneumoniae strain TVO_1901948]
ATGAACAACTTGATTAAACCAAAACTAGAGCTCTTGCCGACCAGCCCTGGTTGCTACATTTACAAGGATAAAAACGGCAC
CATTATCTATGTAGGAAAGGCTAAAAATCTGCGTAATCGCGTGAGGTCTTATTTCCGTGGAAGTCATGATACCAAAACAG
AGGCCTTGGTGTCTGAAATTGTGGATTTTGAATTTATTGTTACGGAGTCTAATATTGAGGCGCTTCTGCTGGAAATCAAC
CTGATCAAGGAAAATAAGCCCAAGTACAATATCATGCTCAAGGATGACAAGTCTTATCCTTTTATCAAAATCACCAATGA
GCACTATCCACGGCTTATCATTACTCGTCAGGTCAAAAAGGACGGTGGTCTTTATTTTGGCCCTTATCCAGATGTGGGGG
CAGCCAATGAAATCAAGCGACTTCTAGATAGGATTTTCCCTTTTCGAAAATGTACCAACCCGCCCTCTAAGGTCTGTTTT
TACTACCATATCGGCCAATGTATGGCCCACACCATCTGTAAGAATGACGAGGCCTATTTCAAGTCCATGGCCCAGGAGGT
GTCTGATTTTCTGAAAGGTCAGGATGACAAAATCATCGATGATCTCAAGAGTAAAATGGCAGTAACAGCACAAAGTATGG
AGTTTGAACGGGCAGCGGAATACCGTGACCTGATTCAGGCCATTGGAACACTTCGAACCAAGCAACGGGTCATGGCTAAG
GATCTCCAAAATCGCGATGTCTTTGGCTACTATGTGGATAAGGGCTGGATGTGTGTGCAGGTTTTCTTTGTTCGTCAGGG
CAAGCTCATCGAGCGCGATGTCAATCTCTTCCCCTACTTCAATGATCCAGATGAGGATTTCTTGACCTATGTGGGACAAT
TCTATCAAGAAAAATCTCACCTAGTTCCCAATGAGGTACTGATTCCGCAGGATATTGACGAAGAAGCTGTCAAGGCTTTG
GTGGATACCAAGATTCTCAAACCCCAACGTGGAGAGAAAAAACAGCTGGTCAATCTAGCCATAAAAAATGCACGTGTTAG
TCTGGAGCAGAAATTTAACCTGCTAGAAAAATCAGTCGAAAAGACCCAAGGAGCTATTGAAAATCTAGGACGTTTGCTCC
AAATTCCGACTCCAGTTCGCATCGAGTCCTTCGATAACTCCAACATCATGGGGACCAGTCCTGTTTCAGCCATGGTGGTC
TTTGTTAACGGCAGGCCAAGTAAAAAAGATTACCGTAAGTACAAGATAAAAACCGTTGTTGGGCCGGACGACTATGCTAG
TATGAGAGAAGTCATTCGCAGACGCTATGGTCGAGTACAGCGTGAGGCTTTGACTCCTCCAGATTTGATTGTGATTGATG
GGGGGCAAGGTCAAGTCAATATTGCTAAGCAAGTCATCCAAGAAGAACTGGGCTTGGATATTCCAATTGCAGGTCTGCAA
AAGAATGATAAGCACCAAACCCATGAACTGCTCTTTGGAGATCCGCTTGAGGTGGTGGACTTGTCTCGCAATTCTCAGGA
ATTTTTCCTCCTCCAACGCATCCAAGATGAGGTGCACCGCTTTGCCATTACCTTCCACCGCCAACTGCGCTCCAAAAATT
CTTTCTCATCTCAATTGGATGGGATTGATGGTCTGGGACCTAAACGCAAGCAAAATCTCATGAGGCACTTCAAGTCTCTG
ACCAAAATCAAGGAAGCCGGTGTGGATGAGATTGTCGAAGTTGGAGTACCAAGAGCAGTAGCAGAGGCTGTGCAAAGAAA
GTTGAACCCGCAGGAAACAGAAATCTTGCTTCAAGTGGCGGAAGAAAGAGTAGATTACCAAACAGAAGGAAACCACAATG
AACCATAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(196-228)

GIY-YIG catalytic domain (GIY-YIG)

(17-90)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

97.724

100

0.977
  uvrC Streptococcus pneumoniae R6

97.724

100

0.977
  uvrC Streptococcus pneumoniae D39

97.724

100

0.977