Detailed information NTG0295249

Bioinformatically predicted

Overview

• Name: pptB
• Type: Regulator
• Locus tag: EQH42_RS02345
• Genome accession: NZ_CP035238
• Coordinates: 475582..476631 (+)
• Length: 349 a.a.
• NCBI ID: WP_000653770.1
• Uniprot ID: Q8DQW6
• Organism: Streptococcus pneumoniae strain TVO_D39
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 470582..481631

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH42_RS02320 (EQH42_02480)	-	471868..472224 (+)	357	WP_000114427.1	hypothetical protein	-
EQH42_RS02325 (EQH42_02485)	dnaJ	472626..473744 (+)	1119	WP_001066302.1	molecular chaperone DnaJ	-
EQH42_RS02330 (EQH42_02490)	-	474079..474366 (-)	288	WP_000777760.1	hypothetical protein	-
EQH42_RS02335 (EQH42_02495)	-	474376..474786 (-)	411	WP_001278301.1	HIT family protein	-
EQH42_RS02340 (EQH42_02500)	pptA	474854..475585 (+)	732	WP_000889919.1	ABC transporter ATP-binding protein	Regulator
EQH42_RS02345 (EQH42_02505)	pptB	475582..476631 (+)	1050	WP_000653770.1	ABC transporter permease	Regulator
EQH42_RS02350 (EQH42_02510)	-	476799..477128 (-)	330	WP_000132569.1	hypothetical protein	-
EQH42_RS02355 (EQH42_02515)	-	477404..477742 (+)	339	WP_000682124.1	LytTR family DNA-binding domain-containing protein	-
EQH42_RS02360 (EQH42_02520)	comE/blpR	477747..478484 (+)	738	WP_001219139.1	response regulator transcription factor	Regulator
EQH42_RS02365 (EQH42_02525)	-	478498..479838 (+)	1341	WP_001017622.1	sensor histidine kinase	-
EQH42_RS02370 (EQH42_02530)	blpC	479880..480035 (-)	156	WP_000358817.1	quorum-sensing system pheromone BlpC	-
EQH42_RS02375 (EQH42_02535)	-	480092..481453 (-)	1362	Protein_472	bacteriocin secretion accessory protein	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 40556.62 Da
• Isoelectric Point: 10.0008

>NTDB_id=295249 EQH42_RS02345 WP_000653770.1 475582..476631(+) (pptB) [Streptococcus pneumoniae strain TVO_D39]
MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYSQLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEA
PDKLFLLVGEEEIKLHLKRQTGISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNLYLRSYLRNGDLFAISLRLLLLS
VLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFDYQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQE
KLALLALLGAGLVLLVLYLPYQVKRQMQD

Nucleotide

• Length: 1050 bp

>NTDB_id=295249 EQH42_RS02345 WP_000653770.1 475582..476631(+) (pptB) [Streptococcus pneumoniae strain TVO_D39]
ATGAAAGACTTGTTTTTAAAGAGAAAGCAGGCCTTTCGTAAGGAGTGTCTTGGTTATCTGCGCTATGTGCTCAATGACCA
CTTTGTCTTGTTCCTGCTTGTCCTGTTGGGCTTTCTAGCCTACCAGTACAGTCAACTCTTACAACATTTTCCTGAAAATC
ATTGGCCTATCCTTTTGTTTGTAGGAATTACGTCTGTTTTACTCTTACTTTGGGGAGGAATTGCCACCTATATGGAGGCT
CCAGACAAGCTCTTTCTCTTAGTTGGAGAAGAGGAAATCAAGCTCCATCTCAAGCGTCAAACTGGCATTTCCCTAGTCTT
TTGGCTCTTTGTACAGACCCTTTTCTTGCTGTTATTTGCGCCTTTATTTTTAGCAATGGGTTATGGCTTGCCAGTTTTTC
TGCTCTATGTGCTTTTATTGGGGGTAGGAAAATATTTCCACTTTCGTCAAAAGGCCAGCAAATTTTTTACTGAAACTGGA
CTGGACTGGGACTATGTTATTTCTCAAGAAAGCAAGCGTAAGCAAGTCTTGCTTCGTTTCTTTGCCCTCTTTACGCAGGT
CAAGGGAATTTCAAACAGCGTTAAGCGTCGTGCCTATCTGGACTTTATCTTAAAGGCTGTTCAGAAGGTGCCTGGGAAGA
TTTGGCAAAATCTCTATCTGCGTTCTTATCTGCGAAATGGCGACCTCTTTGCTATCAGTCTTCGTCTTCTATTACTTTCC
GTACTGGCGCAGGTTTTTATCGAGCAAGCTTGGATTGCGACAGCAGTGGTAGTTCTCTTTAACTACCTCTTGCTCTTCCA
GTTGCTGGCCCTCTATCATGCCTTTGACTACCAGTATTTGACCCAACTCTTTCCGCTGGACAAGGGGCAAAAGGAAAAAG
GCTTACAGGAGGTAGTTCGAGGATTGACCAGTTTTGTTTTACTTGTGGAATTAGTTGTTGGGTTGATTACCTTCCAAGAA
AAACTGGCCCTTCTAGCCTTACTAGGAGCTGGTTTGGTTTTACTAGTCTTGTATTTGCCTTATCAGGTAAAACGTCAGAT
GCAGGACTAA

Domains

Predicted by InterProScan.

• Bacterial ABC transporter protein EcsB (EcsB) (2-156)

• Bacterial ABC transporter protein EcsB (EcsB) (158-331)

3D structure

• AlphaFold DB: Q8DQW6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptB	Streptococcus salivarius strain HSISS4	47.429	100	0.476
pptB	Streptococcus thermophilus LMD-9	46.571	100	0.467