Detailed information NTG0295149

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: CSB71_RS08500
• Genome accession: NZ_CP029680
• Coordinates: 1531253..1532239 (-)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain AR_0215
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 1526253..1537239

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CSB71_RS08475 (CSB71_1536)	-	1526513..1526860 (-)	348	WP_001242103.1	hypothetical protein	-
CSB71_RS08480 (CSB71_1537)	-	1527046..1527639 (+)	594	WP_000224619.1	CYTH domain-containing protein	-
CSB71_RS08485 (CSB71_1538)	-	1527743..1528108 (+)	366	WP_000214070.1	truncated hemoglobin YjbI	-
CSB71_RS08490 (CSB71_1539)	yjbH	1528131..1528937 (+)	807	WP_000896697.1	protease adaptor protein YjbH	-
CSB71_RS08495 (CSB71_1540)	pepF	1529397..1531205 (-)	1809	WP_001655747.1	oligoendopeptidase F	-
CSB71_RS08500 (CSB71_1541)	coiA	1531253..1532239 (-)	987	WP_000959282.1	competence protein CoiA family protein	Machinery gene
CSB71_RS08505 (CSB71_1542)	mecA	1532360..1533079 (-)	720	WP_001217728.1	adaptor protein MecA	-
CSB71_RS08510 (CSB71_1543)	spxA	1533450..1533845 (-)	396	WP_000258003.1	transcriptional regulator SpxA	-
CSB71_RS08515 (CSB71_1544)	trpS	1534139..1535128 (+)	990	WP_000448934.1	tryptophan--tRNA ligase	-
CSB71_RS08520 (CSB71_1545)	opp4C	1535170..1536051 (-)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
CSB71_RS08525 (CSB71_1546)	opp4B	1536063..1537025 (-)	963	WP_000915997.1	oligopeptide ABC transporter permease	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=295149 CSB71_RS08500 WP_000959282.1 1531253..1532239(-) (coiA) [Staphylococcus aureus strain AR_0215]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=295149 CSB71_RS08500 WP_000959282.1 1531253..1532239(-) (coiA) [Staphylococcus aureus strain AR_0215]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976