Detailed information
Bioinformatically predicted
Overview
| Name | ccrB | Type | Machinery gene |
| Locus tag | CSB76_RS00480 | Genome accession | NZ_CP029673 |
| Coordinates | 61865..63493 (-) | Length | 542 a.a. |
| NCBI ID | WP_001186602.1 | Uniprot ID | Q9XB94 |
| Organism | Staphylococcus aureus strain AR_0220 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 56644..100369 | 61865..63493 | within | 0 |
| SCCmec | 43524..64864 | 61865..63493 | within | 0 |
Gene organization within MGE regions
Location: 43524..100369
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CSB76_RS00365 (CSB76_0039) | mecA | 43524..45533 (-) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| CSB76_RS00370 (CSB76_0040) | mecR1 | 45630..47387 (+) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| CSB76_RS00375 (CSB76_0041) | mecI | 47387..47758 (+) | 372 | WP_000369214.1 | mecA-type methicillin resistance repressor MecI | - |
| CSB76_RS00380 | psm-mec | 47843..47911 (-) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| CSB76_RS00385 (CSB76_0042) | - | 48245..49375 (+) | 1131 | WP_010922808.1 | ROK family transcriptional regulator | - |
| CSB76_RS00395 (CSB76_0044) | cstB | 49489..50823 (-) | 1335 | Protein_39 | persulfide dioxygenase-sulfurtransferase CstB | - |
| CSB76_RS00400 (CSB76_0045) | - | 50856..51920 (-) | 1065 | WP_000438836.1 | DsrE/DsrF/DrsH-like family protein | - |
| CSB76_RS00405 (CSB76_0046) | cstR | 52056..52316 (+) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| CSB76_RS00410 (CSB76_0047) | - | 52316..52954 (+) | 639 | Protein_42 | sulfite exporter TauE/SafE family protein | - |
| CSB76_RS00420 (CSB76_0048) | - | 53299..53961 (-) | 663 | WP_110417900.1 | class I SAM-dependent methyltransferase | - |
| CSB76_RS00435 (CSB76_0049) | erm(A) | 54470..55201 (+) | 732 | WP_001072201.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A) | - |
| CSB76_RS00440 (CSB76_0050) | - | 55327..56109 (-) | 783 | WP_000067268.1 | aminoglycoside nucleotidyltransferase ANT(9)-Ia | - |
| CSB76_RS00445 (CSB76_0051) | - | 56260..56637 (-) | 378 | WP_000361059.1 | DUF6262 family protein | - |
| CSB76_RS00450 (CSB76_0052) | - | 56644..58536 (-) | 1893 | WP_001557544.1 | site-specific integrase | - |
| CSB76_RS00455 (CSB76_0053) | - | 58533..59618 (-) | 1086 | WP_000868132.1 | tyrosine-type recombinase/integrase | - |
| CSB76_RS00460 (CSB76_0054) | - | 59737..60054 (-) | 318 | WP_000659050.1 | JAB domain-containing protein | - |
| CSB76_RS00465 (CSB76_0055) | - | 60075..60581 (-) | 507 | WP_001092169.1 | DUF1643 domain-containing protein | - |
| CSB76_RS00470 (CSB76_0056) | - | 60599..60910 (-) | 312 | WP_000700853.1 | DUF960 family protein | - |
| CSB76_RS00475 (CSB76_0057) | - | 60997..61347 (-) | 351 | WP_000859155.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| CSB76_RS00480 (CSB76_0058) | ccrB | 61865..63493 (-) | 1629 | WP_001186602.1 | recombinase family protein | Machinery gene |
| CSB76_RS00485 (CSB76_0059) | ccrA | 63515..64864 (-) | 1350 | WP_000815646.1 | recombinase family protein | Machinery gene |
| CSB76_RS00490 (CSB76_0060) | - | 65098..66891 (-) | 1794 | WP_000195105.1 | DUF927 domain-containing protein | - |
| CSB76_RS00495 (CSB76_0061) | - | 66891..67187 (-) | 297 | WP_000273824.1 | single-stranded DNA-binding protein | - |
| CSB76_RS00500 (CSB76_0062) | - | 67380..68426 (-) | 1047 | WP_001060127.1 | hypothetical protein | - |
| CSB76_RS00505 | - | 68677..69818 (-) | 1142 | Protein_58 | IS3-like element ISSau4 family transposase | - |
| CSB76_RS00510 | - | 70329..71255 (-) | 927 | Protein_59 | YfcC family protein | - |
| CSB76_RS00515 (CSB76_0069) | - | 71977..72672 (-) | 696 | WP_000858967.1 | response regulator transcription factor | - |
| CSB76_RS00520 (CSB76_0070) | - | 72647..75316 (-) | 2670 | WP_031871837.1 | sensor histidine kinase KdpD | - |
| CSB76_RS00525 | kdpF | 75483..75563 (+) | 81 | WP_000631574.1 | K(+)-transporting ATPase subunit F | - |
| CSB76_RS00530 (CSB76_0071) | kdpA | 75584..77260 (+) | 1677 | WP_000029430.1 | potassium-transporting ATPase subunit KdpA | - |
| CSB76_RS00535 (CSB76_0072) | - | 77279..79300 (+) | 2022 | WP_000852430.1 | K(+)-transporting ATPase subunit B | - |
| CSB76_RS00540 (CSB76_0073) | - | 79316..79873 (+) | 558 | WP_001193482.1 | K(+)-transporting ATPase subunit C | - |
| CSB76_RS00545 (CSB76_0074) | - | 80418..81287 (-) | 870 | WP_000626133.1 | hypothetical protein | - |
| CSB76_RS00550 (CSB76_0075) | - | 81297..82193 (-) | 897 | WP_000411461.1 | DUF927 domain-containing protein | - |
| CSB76_RS00560 (CSB76_0077) | - | 83312..83938 (-) | 627 | WP_001176969.1 | hypothetical protein | - |
| CSB76_RS00565 (CSB76_0078) | - | 84053..85561 (+) | 1509 | WP_001001347.1 | protein kinase | - |
| CSB76_RS00570 | - | 85811..85945 (-) | 135 | WP_001790628.1 | hypothetical protein | - |
| CSB76_RS00575 | - | 85909..86001 (+) | 93 | WP_001790000.1 | hypothetical protein | - |
| CSB76_RS00580 (CSB76_0079) | - | 86148..87893 (+) | 1746 | WP_000700190.1 | DUF6119 family protein | - |
| CSB76_RS00585 (CSB76_0080) | - | 87991..88346 (-) | 356 | Protein_73 | tRNA-dihydrouridine synthase | - |
| CSB76_RS00590 | - | 88651..88739 (-) | 89 | Protein_74 | hypothetical protein | - |
| CSB76_RS00595 (CSB76_0081) | - | 88837..89592 (-) | 756 | WP_000355845.1 | sulfite exporter TauE/SafE family protein | - |
| CSB76_RS00600 (CSB76_0082) | cstR | 89592..89852 (-) | 261 | WP_001105088.1 | persulfide-sensing transcriptional repressor CstR | - |
| CSB76_RS00605 (CSB76_0083) | cstA | 89989..91053 (+) | 1065 | WP_000816133.1 | persulfide response sulfurtransferase CstA | - |
| CSB76_RS00610 (CSB76_0084) | cstB | 91084..92418 (+) | 1335 | WP_000465472.1 | persulfide dioxygenase-sulfurtransferase CstB | - |
| CSB76_RS00615 (CSB76_0085) | sqr | 92437..93630 (+) | 1194 | WP_001033018.1 | type II sulfide:quinone oxidoreductase Sqr | - |
| CSB76_RS15090 | - | 93897..94111 (-) | 215 | Protein_80 | universal stress protein | - |
| CSB76_RS00630 (CSB76_0086) | - | 94297..95283 (-) | 987 | WP_000662022.1 | tRNA-dihydrouridine synthase | - |
| CSB76_RS00635 | - | 95592..95795 (+) | 204 | WP_000389759.1 | DUF6007 family protein | - |
| CSB76_RS00640 (CSB76_0087) | - | 95844..96140 (+) | 297 | WP_000201644.1 | TfoX/Sxy family protein | - |
| CSB76_RS00645 (CSB76_0088) | - | 96348..96950 (+) | 603 | WP_000908956.1 | hypothetical protein | - |
| CSB76_RS00650 (CSB76_0089) | - | 97217..100369 (+) | 3153 | WP_000080564.1 | DEAD/DEAH box helicase | - |
Sequence
Protein
Download Length: 542 a.a. Molecular weight: 62664.84 Da Isoelectric Point: 9.8600
>NTDB_id=294991 CSB76_RS00480 WP_001186602.1 61865..63493(-) (ccrB) [Staphylococcus aureus strain AR_0220]
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
Nucleotide
Download Length: 1629 bp
>NTDB_id=294991 CSB76_RS00480 WP_001186602.1 61865..63493(-) (ccrB) [Staphylococcus aureus strain AR_0220]
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrB | Staphylococcus aureus N315 |
100 |
100 |
1 |