Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   EQH45_RS02055 Genome accession   NZ_CP035235
Coordinates   401518..402150 (+) Length   210 a.a.
NCBI ID   WP_000698434.1    Uniprot ID   Q9S1J7
Organism   Streptococcus pneumoniae strain TVO_1902276     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 396518..407150
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH45_RS02030 (EQH45_02155) mvaD 396796..397749 (+) 954 WP_000373457.1 diphosphomevalonate decarboxylase -
  EQH45_RS02035 (EQH45_02160) - 397736..398743 (+) 1008 WP_000562425.1 phosphomevalonate kinase -
  EQH45_RS02040 (EQH45_02165) fni 398727..399737 (+) 1011 WP_000210625.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  EQH45_RS02045 (EQH45_02170) liaF 399814..400512 (+) 699 WP_001224637.1 cell wall-active antibiotics response protein LiaF -
  EQH45_RS02050 (EQH45_02175) - 400509..401504 (+) 996 WP_000743659.1 sensor histidine kinase -
  EQH45_RS02055 (EQH45_02180) vraR 401518..402150 (+) 633 WP_000698434.1 response regulator transcription factor Regulator
  EQH45_RS02060 - 402226..402919 (+) 694 Protein_410 DNA alkylation repair protein -
  EQH45_RS02065 (EQH45_02200) - 403069..403308 (+) 240 WP_000754501.1 hypothetical protein -
  EQH45_RS02070 (EQH45_02205) cbpG 403389..404210 (+) 822 WP_001100136.1 choline-binding protein CbpG -
  EQH45_RS02075 (EQH45_02210) cbpF 404229..405251 (+) 1023 WP_000771059.1 choline-binding protein CbpF -
  EQH45_RS02080 (EQH45_02215) - 405379..406727 (-) 1349 Protein_414 IS3 family transposase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23553.03 Da        Isoelectric Point: 4.5791

>NTDB_id=294895 EQH45_RS02055 WP_000698434.1 401518..402150(+) (vraR) [Streptococcus pneumoniae strain TVO_1902276]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=294895 EQH45_RS02055 WP_000698434.1 401518..402150(+) (vraR) [Streptococcus pneumoniae strain TVO_1902276]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGATTGGGCTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAATATTCTTGCCAAACT
TGAAGTCAGCGATCGTACCCAGGCGGCTGTCTATGCCTTTCAGCACCATTTGGTGGGGCAAGAGGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9S1J7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41